Mean-standard deviation based electric vehicle routing problem using Lagrangian relaxation and extended alternating direction method of multipliers based decomposition algorithm

 This is the experimental data of the manuscript entitled “   Mean-standard deviation based electric vehicle routing problem using Lagrangian relaxation and extended alternating direction method of multipliers based decomposition algorithm”. In this data set, small and large instances are included, and each instance gives the information of the links, such as the start node, end node and  variance of the link.</p

Mean-standard deviation based electric vehicle routing problem using Lagrangian relaxation and extended alternating direction method of multipliers based decomposition algorithm

This is the experimental data of the manuscript entitled “   Mean-standard deviation based electric vehicle routing problem using Lagrangian relaxation and extended alternating direction method of multipliers based decomposition algorithm”. In this data set, small and large instances are included, and each instance gives the information of the links, such as the start node, end node and  variance of the link.</p

Nitrogen-Doped Carbon Polyhedra Nanopapers: An Advanced Binder-Free Electrode for High-Performance Supercapacitors

Metal–organic framework (MOF)-derived nitrogen-doped porous carbon as electrode material for supercapacitors has recently drawn much attention. However, the development of flexible electrodes composed of MOF-derived carbon is still a great challenge. Herein, nitrogen-doped porous carbon polyhedra (NC) derived from zeolitic imidazolate framework-8 (ZIF8) are assembled into flexible nanopapers assisted with reduced graphene oxide (rGO). The resultant NC/rGO nanopaper shows a hierarchical structure of NC nanoparticle-imbedded rGO framework. A uniform dispersion of NC nanoparticles is achieved due to the rGO framework, and meanwhile, the uniform decoration of NC nanoparticles on rGO nanosheets prevents easy restacking of rGO. A conductive rGO framework further accelerates the electron/ion transportation inside the NC/rGO nanopaper. Furthermore, excellent mechanical performance of rGO framework endows high flexibility to the NC/rGO nanopaper. As a result, the NC/rGO nanopaper as a binder-free electrode delivers high specific capacitance of 280 F g–1 at 1 A g–1, high capacitance retention after 5000 cycles, and high energy density of 19.45 W h kg–1

Hierarchical Nanostructures of Nitrogen-Doped Porous Carbon Polyhedrons Confined in Carbon Nanosheets for High-Performance Supercapacitors

Interconnected close-packed nitrogen-doped porous carbon polyhedrons (NCPs) confined in two-dimensional carbon nanosheets (CNSs) have been prepared through a sustainable one-pot pyrolysis of a simple solid mixture of zeolitic imidazolate framework-8 (ZIF-8) crystals and with organic potassium as the precursors. The hierarchically organized framework of the NCP–CNS composites enables NCPs and CNSs to act as well-defined electrolyte reservoirs and mechanical buffers accommodating large volume expansions of NCPs, respectively. Among the unique composite nanostructures, the NCPs with vast micropores provide electric double-layer capacitances, while the CNSs bridge the individual NCPs to form a conductive pathway with a hierarchical porosity. As a result, the NCP–CNS composites with high electrical integrity and structural stability are used as electrode materials for high-performance supercapacitors, which exhibit excellent electrochemical capacitive characteristics in terms of an outstanding capacitance of 300 F g^–1 at 1 A g^–1, large energy density of 20.9 W h kg^–1, and great cycling performance of 100% retention after 6000 cycles. This work therefore presents a one-pot and efficient strategy to prepare an ordered arrangement of ZIF-8-derived porous carbons toward new electrode materials in promising energy storage systems

Simultaneous determination of polarization states and mode coefficients of fiber LP modes with four-channel off-axis holography

Four-channel off-axis holography is proposed to simultaneously understand the polarization states and the mode coefficients of LP modes in few-mode fiber. Far-field off-axis holograms in the four-polarization directions of the fiber laser were acquired at the same moment through a four-channel holographic device. The weights, the relative phase differences and the polarization parameters of the vector fiber laser mode can be solved simultaneously. The simulated and experimental mode analysis of the laser output by 1060-XP fiber with 6 LP modes at 632.8nm are conducted, which shows that the similarity of the total intensity distribution of the laser before and after mode analysis is above 0.97. The mode polarization states, the mode weights and the relative phase differences of the few-mode laser can be determined simultaneously in a single shot by the four-channel off-axis holography

DataSheet_1_The utility of high-frequency 18 MHz ultrasonography for preoperative evaluation of acral melanoma thickness in Chinese patients.pdf

BackgroundDespite the increasing use of preoperative ultrasound evaluation for melanoma, there is limited research on the use of this technique for Acral Melanoma (AM).MethodsThis retrospective study analyzed the electronic medical records of patients who underwent preoperative evaluation for cutaneous melanoma maximum thickness using an 18 MHz probe and histopathological examination between December 2017 and March 2021 at the Department of Dermatology in Xiangya Hospital, Central South University.ResultsA total of 105 patients were included in the study. The mean tumor thickness was 3.9 mm (s.d., 2.3), with 63% of the specimens showing ulceration and 44 patients showing lymph node metastasis. The results showed a good correlation between the high-frequency ultrasonography (HFUS) and histopathological thickness measurements, with a Spearman’s correlation coefficient of 0.83 [(95% CI 0.73–0.90) (P ConclusionOur study suggests that high-frequency 18 MHz ultrasonography is an effective tool for the preoperative evaluation of AM thickness. The HFUS measurements correlated well with the histopathological thickness measurements, making it a valuable and reliable method for clinicians to assess the thickness of melanoma lesions preoperatively.</p

Anti-gastric cancer effect of Salidroside through elevating miR-99a expression

Salidroside is an active ingredient extracted from Rhodiola rosea that has anti-tumor activities. The current paper attempted to assess the impact of Salidroside on gastric cancer (GC) and explore the potential mechanism. GC cell lines (SNU-216 and MGC803) and gastric epithelial cell line GES-1 were treated with Salidroside. CCK-8 assay, colony formation assay, flow cytometry and Transwell assay were respectively performed to evaluate GC cells phenotype. qRT-PCR and western blot were conducted to reveal the downstream genes and signaling of Salidroside. We found that 800 μM Salidroside was capable of reducing GC cells viability, while has no such impacts on GES-1 cells. Salidroside inhibited GC cells proliferation, migration, invasion and promoted apoptosis, which coupled with the down-regulation of p21, Bcl-2, MMP2, RhoA, p-ROCK1, Vimentin and the up-regulations of CyclinD1, Bax, cleaved caspases. miR-99a was found to be highly expressed in response to Salidroside treatment. Besides, the inhibition of MAPK/ERK and PI3K/AKT signaling induced by Salidroside was attenuated by miR-99a silence and in this process, IGF1R worked as a target of miR-99a. The anti-GC effect of Salidroside was also confirmed in a mouse model of GC. The promoting effect of Salidroside on miR-99a expression was also verified in vivo. Furthermore, Salidroside promoted the cisplatin-sensitivity of SGC7901/DDP cells. In conclusion, this study demonstrated that Salidroside possessed anti-GC effects through regulating miR-99a/IGF1R axis and inhibiting MAPK/ERK and PI3K/AKT pathways.</p

Additional file 1 of Short-term PM2.5 and cardiovascular admissions in NY State: assessing sensitivity to exposure model choice

Additional file 1: Table S1. Descriptive statistics by season. Table S2. Descriptive statistics by quartiles of rural population. Table S3. Descriptive statistics for complete-case analysis. Table S4. Percent increase in daily CVD admissions and 95% confidence intervals (CI) per 10 µg/m3 for all PM2.5 products. Table S5. Quasi-Akaike’s Information Criterion (qAIC) for select seasonal and long-term trends. Figure S1. Percent increase in daily CVD admissions rates per interquartile range for all PM2.5 products. Figure S2. Percent increase in daily CVD admissions rates for subset excluding AQS. Figure S3. Percent increase in lag 0–1 CVD admissions rates per 10 µg/m3 for all PM2.5 products. Figure S4. Sensitivity analysis adding bank holiday as a potential confounder. Figure S5. Time series of average PM2.5 exposure estimates by PM2.5 product

Photodynamic therapy combined with surgery versus Mohs micrographic surgery for the treatment of difficult-to-treat basal cell carcinoma: a retrospective clinical study

Mohs micrographic surgery (MMS) is the preferable surgery for difficult -to-treat basal cell carcinoma (BCC) but is an expensive, labor-intensive, and time-consuming technique. The aim of this study is to compare the efficacy and safety of photodynamic therapy combined with surgery(S-PDT) versus Mohs micrographic surgery (MMS) for the treatment of difficult-to-treat BCC. This was a retrospective, comparative study. A total of 32 patients, 16 patients with 48 lesions, were treated with S-PDT, and the other 16 patients with 17 lesions treated by MMS were enrolled in this study. Follow-up was at least 36 months posttreatment. The recurrence rate was no statistical difference between the S-PDT and MMS (p = 1.000, Fishers exact test). The median follow-up was 42.5 months (range 36–63 months). The mean healing time in the S-PDT [17.9 d (SD 9.8)] is longer than in MMS [7.5 d (SD 1.5)] during follow-up (p＜.001, Independent T-test). On the whole, the cosmetic outcome of patients in S-PDT was statistically no significant difference with that in MMS according to a 4-point scale (p = .719, chi-squared test). S-PDT is a safe, effective, and novel cosmetic treatment, which holds the potential to be an alternative treatment to MMS for some cases.</p