2,198 research outputs found
THE EFFECT OF SHODHAN PROCESS ON TOXICITY OF UPAVISHA KUPEELU BEEJA (STRYCHNOS NUXVOMICA): A CRITICAL STUDY
The principle objectives of Ayurveda are to promote perfect health and to prolong life and to completely eradicate the disease and dysfunction of the body. Charaka opined that a deadly poison can become a very good medicine if it is administered in a proper way and with proper technique. Various processes of purification, especially for Visha and Upvisha,are mentioned in Ayurvedic texts. They are called as Shodhan sanskar (detoxification procedure). Shodhana is the process which involves the conversion of any poisonous drug into a medicinally useful and harmless drug. Kupeelu beeja (Strychnos nuxvomica), a Sthavara vanaspatij visha contains spinal neurotoxic poison, strychnine. But pure Kupeelu beeja has many therapeutic properties as well. So, it is necessary to subject Kupeelu beeja to detoxification (Shodhana) process before using it as medicine. To prove the authenticity and safety of the use of purified and Shodhit Vishadravya (detoxified poisonous drugs), it must be subjected to modern parameters. In this article, attempt has been made to study the changes in phyto-chemical properties and LD50 values of Kupeelu beeja churna (Strychnos nuxvomica seed powder) due to Shodhan sanskar. The detoxification of Strychnos nuxvomica seeds was done by boiling it in cow’s milk for 3 hrs. Then the seeds coverings were scrapped and embryo was removed and dried. Thereafter, a fine powder was prepared and stored. This detoxified powder (Shodhit Kupeelu beeja churna) was used in studying phytochemical properties and animal experiment in comparison with the powder of non detoxified Strychnos nuxvomica seeds (Ashodhit Kupeelu beeja churna). The study revealed that the detoxification process of Strychnos nux vomica seed powder affects its physico-chemical properties. Shodhana process increases the value of LD50 of Kupeelu beeja churna. i.e. it reduces the toxicity of Kupeelu beeja churna. Thus the safety of the detoxified drug can be established
Abdominal incisional hernia: retrospective study
Background: Incisional hernia presents as herniation or protrusion occurring along a prior abdominal scar. It is a known complication of abdominal surgery. They are the second most common type of hernia after inguinal hernias. This study was undertaken to study the incidence and various risk factors leading to incisional hernia.Methods: It is a retrospective study done in Gandhi Medical College, Bhopal; Department of Surgery during January 2017 to January 2018. All the cases were analyzed in various aspects like age, sex, relative incidence, clinical presentation, nature of previous operation, site of previous scar, precipitating factors like obesity, wound infection, abdominal distension.Results: The incidence is around 18.5%. Patients in the age group of 30-50 years found to have highest incidence of incisional hernia. Females outnumbered the males with the ratio of 6:1. Incisional hernia was more common in patients with previous history of gynecological operation. Most of the patients presented with incisional hernia in the infra umbilical region.Conclusions: Incisional hernias can be prevented by avoidance of midline incisions, especially in the infra umbilical region. Mesh repair results in less post-operative complications provided drains are used
Growth of Indian library and information science literature: A study of Annals of Library and Information Studies
209-214The growth of the LIS literature of 1985-90 and 2005-2010 as reflected through Annals of Library and Information Studies is studied. The paper examines the year-wise growth of the library and information science literature, subjects covered during the specified periods, the most used form of literature, authorship pattern, and most cited journals. Among other things, the study finds that a few areas of research such as ICT applications in LIS are more during the period 2005-2010
Silver ion conducting nanocomposite polymer electrolytes: Ion transport and battery fabrication
Ion transport characterization studies on a new Ag+ ion conducting (poly-ethylene oxide) PEO-based nanocomposite electrolytes (NCPEs): (1-x) [30PEO:70(0.75AgI:0.25AgCl)] + x SiO2, where 0<x<20 wt.%, have ben reported. A novel hot-press/ solvent free technique has been used for the formation of the present NCPE films. Nano-size (~ 8 nm) SiO2 particles have been dispersed as a second dispersoid in to the first phase host matrix: [30PEO:70(0.75AgI:0.25AgCl)], identified as the highest conducting polymer electrolyte composition. A conductivity enhancement of more two orders that of the pure polymer-electrolyte host could be achieved in the nano-composite polymer electrolyte composition: 95[30PEO:70(0.75AgI:0.25AgCl)] + 5SiO2 (σ ~ 6.2 × 10-5 S.cm-1) and this has been referred to as optimum conducting composition (OCC). Polymer-salt/ nano-filler complexations have been explained with the help of XRD, DSC and TGA analysis. To explain the ion transport characterization various ionic transport parameters viz. conductivity (σ), ionic mobility (μ), mobile ion concentration (n), ionic transference number (tion) etc. have been determined at room temperature and the temperature dependent conductivity measurements have also been carried out to evaluate the activation energy (Ea). A new Ag+ ion conducting solid state polymer battery have been fabricated and studied the cell parameters at room temperature
Growth of Indian library and information science literature: A study of Annals of Library and Information Studies
The growth of the LIS literature of 1985-90 and 2005-2010 as reflected through Annals of Library and Information Studies is studied. The paper examines the year-wise growth of the library and information science literature, subjects covered during the specified periods, the most used form of literature, authorship pattern, and most cited journals. Among other things, the study finds that a few areas of research such as ICT applications in LIS are more during the period 2005-2010
Pentatrichomonas hominis in an immunosuppressed patient with enteric manifestations
Pentatrichomonas hominis is a flagellated protozoa considered to be a commensal that inhabits caecum and large intestine in man. It is regarded to be non-pathogenic, however, it has been postulated that these trichomonads undergo multiplication under favorable conditions for growth and exhibit a form of opportunism eventually causing diarrhea. We report, for the first time in India, a case of diarrhea due to P. hominis in an elderly male with myeloid malignancy that resolved on treatment with metronidazole
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