Additional file 1: of Quality of conduct and reporting in rapid reviews: an exploration of compliance with PRISMA and AMSTAR guidelines

Search Strategy. Search Strategy and MeSH/keywords used for searching. (DOCX 32 kb

Additional file 2: of Quality of conduct and reporting in rapid reviews: an exploration of compliance with PRISMA and AMSTAR guidelines

Included and Excluded Study Lists. Details the sample of rapid reviews included in this manuscript and reports excluded studies. (DOCX 27 kb

Supplemental Material for Huang et al., 2018

Supplementary tables contain genotype and phenotype of Oryza accessions included in the study, and genomic regions sequenced by target capture. Figure S1 contains phylogeny tree based on SNPs.A series of in-house Perl scripts to convert the polymorphisms from variant call format (VCF) to FASTA format; estimate of nucleotide diversity including Nei’s average pairwise nucleotide diversity (π) and Watterson’s estimator of theta (θw)Fasta format files of gene fragments (~1500 base pair) upstream and downstream of the five candidate genes. These fragments were captured following the Agilent (Agilent, Santa Clara, CA) SureSelect Target Enrichment method (Gnirke et al., 2009). A total of 123 loci close to the five candidate genes were targeted and sequenced (Table S2)</div

Effectiveness of iPad apps on visual-motor skills among children with special needs between 4y0m–7y11m

<p><b>Aims:</b> The aim of this randomized controlled trial was to assess the effectiveness of interventions using iPad applications compared to traditional occupational therapy on visual-motor integration (VMI) in school-aged children with poor VMI skills.</p> <p><b>Methods:</b> Twenty children aged 4y0m to 7y11m with poor VMI skills were randomly assigned to the experimental group (interventions using iPad apps targeting VMI skills) or control group (traditional occupational therapy intervention sessions targeting VMI skills). The intervention phase consisted of two 40-min sessions per week, over a period of 10 weeks. Participants were required to attend a minimum of 8 and a maximum of 12 sessions. The subjects were tested using the Beery-VMI and the visual-motor subscale of the M-FUN, at baseline and follow-up.</p> <p><b>Results:</b> Results from a 2-way mixed design ANOVA yielded significant results for the main effect of time for the M-FUN total raw score, as well as in the subscales Amazing Mazes, Hidden Forks, Go Fishing and VM Behavior. However, gains did not differ between intervention types over time. No significant results were found for the Beery-VMI.</p> <p><b>Conclusions:</b> This study supports the need for further research into the use of iPads for the development of VMI skills in the pediatric population.Implications for Rehabilitation</p><p>This is the first study to look at the use of iPads with school-aged children with poor visual-motor skills.</p><p>There is limited literature related to the use of iPads in pediatric occupational therapy, while they are increasingly being used in practice.</p><p>When compared to the traditional occupational therapy interventions, participants in the iPad intervention appeared to be more interested, engaged and motivated to participate in the therapy sessions.</p><p>Using iPad apps as an adjunct to therapy in intervention could be effective in improving VMI skills over time.</p><p></p> <p>This is the first study to look at the use of iPads with school-aged children with poor visual-motor skills.</p> <p>There is limited literature related to the use of iPads in pediatric occupational therapy, while they are increasingly being used in practice.</p> <p>When compared to the traditional occupational therapy interventions, participants in the iPad intervention appeared to be more interested, engaged and motivated to participate in the therapy sessions.</p> <p>Using iPad apps as an adjunct to therapy in intervention could be effective in improving VMI skills over time.</p

Table 1

Comparison of results with final SCD genotype classification within the REDS-III Brazil SCD cohort stud

DataStrokeSE - BMJ Open

RCT data for Stroke or SE for Atrial Fibrillation - WinBUG

DataMajorBleeding - BMJ Open

RCT data for Major Bleeding in Atrial Fibrillation - WinBUG

Comparison of Pyrosequencing results with final SCD classification, REDS-III Brazil SCD cohort study.

Comparison of Pyrosequencing results with final SCD classification, REDS-III Brazil SCD cohort study.</p

Distribution of SCD patients according to different tests, REDS-III Brazil SCD cohort study.

Distribution of SCD patients according to different tests, REDS-III Brazil SCD cohort study.</p

HIV Infectivity of PBMCs from SCD Patients and non-SCD Controls.

CD8-depleted PBMC from SCD patients and non-SCD controls were infected with HIV NL4-3 (CXCR4-tropic) and 81-A (CCR5-tropic) at increasing MOI for six days. Following incubation, supernatants and cells were harvested for detection of HIV p24 (Panel A) and pro-viral load (Panel B) respectively. Mean and standard errors of the means for 30 SCD patients and 30 non-SCD controls are shown. Samples from four SCD patients and two non-SCD controls spanning a range of proviral load were assayed for integrated HIV DNA (Panel C). Five samples showed undetectable HIV DNA on both assays and are not graphed. The linear regression line of the log10 values is shown.</p