55 research outputs found

    佐倉牧跡における集落の形成過程

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    2wave KLoSA Questionnaire English version_2008. (PDF 1412 kb

    of Disc haemorrhage associated with an enlarged peripapillary intrachoroidal cavitation in a non-glaucomatous myopic eye: a case report

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    of Disc haemorrhage associated with an enlarged peripapillary intrachoroidal cavitation in a non-glaucomatous myopic eye: a case repor

    Asymmetric Synthesis of Quaternary α-Amino Phosphonates Using Sulfinimines

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    The addition of lithium diethylphosphonate to enantiopure ketosulfinimines is highly diastereoselective (>95%), affording the first examples of quaternary α-alkyl α-amino (arylmethyl)phosphonates

    Applications of the Sulfinimine-Mediated Asymmetric Strecker Synthesis to the Synthesis of α-Alkyl α-Amino Acids

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    Addition of Et2AlCN and i-PrOH to ketosulfinimines (N-sulfinyl imines) affords corresponding α-alkyl α-amino nitriles in moderate to good yields. The diastereoselectivity is largely dependent on the E/Z isomer ratio of the ketosulfinimine. Hydrolysis of the diastereomerically pure amino nitriles affords enantiopure α-alkyl α-amino acids in moderate to good yields
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