Crosstab of the results obtained from 57 baboon and 11 control samples.

<p>Crosstab of the results obtained from 57 baboon and 11 control samples.</p

Definitions used to determine the infectious stage of baboons.

<p>Definitions used to determine the infectious stage of baboons.</p

Multiple comparisons of log anti-<i>T</i>. <i>pallidum</i> titers in 4 groups with a different stage of genital ulceration in baboons

<p>([CNA] = clinically non-affected (n = 20), [INI] = initial (n = 14), [MOD] = moderate (n = 7), and [SEV] = severe genital ulceration (n = 16); for stage definition see [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003637#pntd.0003637.ref018" target="_blank">18</a>]), GU = genital ulceration. Anti-<i>T</i>. <i>pallidum</i> antibody quantification was investigated using the Serodia TP-PA. Kruskal-Wallis test using Dunn’s correction for multiple comparison: CNA vs. SEV mean rank diff. = -30.04, p ≤ 0.0001; CNA vs. MOD mean rank diff. = -19.95, p ≤ 0.05; INI vs. SEV mean rank diff. = -17.56, p ≤ 0.05. (mean ± SEM).</p

Comparison of the serological tests with the consensus of infection status (Table 2).

<p>Comparison of the serological tests with the consensus of infection status (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003637#pntd.0003637.t002" target="_blank">Table 2</a>).</p

PCG duration model by females.

GLMMs evaluating if the duration of female PCG was affected by the presence of copulation calls and type of copulation (ejaculatory vs non-ejaculatory).</p

Definition of behavioral variables.

Definition of behavioral variables.</p

Performance characteristics of the serological tests used in this study, as reported by the manufacturer. Sen = Sensitivity, Spec = Specificity, n.p. = not provided.

<p>Performance characteristics of the serological tests used in this study, as reported by the manufacturer. Sen = Sensitivity, Spec = Specificity, n.p. = not provided.</p

<i>T</i>. <i>pallidum</i> test algorithm for the screening of wild non-treated baboons.

<p>Based on the test performances Espline TP is recommended as the initial screening test followed by a confirmatory test e.g. Mastablot TP IgG that has been identified as most reliable standard. Dashed lines indicate reported results, while continuous lines represent the workflow.</p

Comparison of treponemal serological tests with the results of the Serodia TP-PA.

<p>Comparison of treponemal serological tests with the results of the Serodia TP-PA.</p

Female copulation call interaction model.

Binary GLMM evaluating if the likelihood of uttering a copulation call is affected by the male and female GHS and the type of copulation. Estimates, standard errors (SE), z-values, and 2.5% and 97.5% confidence intervals (CI) are shown for fixed effects. Intercept with a reference category for ulcerated individuals and ejaculatory events. (DOCX)</p