Evaluation of anti-cancer effect of zerumbone and cisplatin on <i>N</i>-nitrosodiethylamine induced hepatic cancer in freshwater fish (<i>Danio rerio</i>)

Cancer is the uncontrolled proliferation of abnormal cells in the body. There is a foreseeable need for an effective anti-carcinogenic drug. In this regard, zerumbone (ZER) is identified as one such therapeutic herbal compound that has been shown to enhance the anticancer activity of cisplatin (CIS), with negligible side effects. Yet, the fundamental mechanisms of co-treatment of ZER and CIS on Hepatocellular carcinoma remain indefinable. The current study is endeavored to evaluate the anti-cancer effect of the individual and co-treatment of ZER, CIS and its combination on Diethyl nitrosamine induced hepatic cancer in wild-type zebra fish (Danio Rerio) models. Our careful analysis on treated and untreated fishes shows that CIS + ZER combination group restricted further progression of hepatocellular carcinoma cells significantly, which concludes that co-treatment of ZER with CIS was therapeutically effective for treating human HCC cancer cells which were induced into zebra fish.</p

sj-pdf-1-cat-10.1177_10760296231213632 - Supplemental material for Shell Versus Core Architecture and Biology of Thrombi in Acute Ischemic Stroke: A Systematic Review

Supplemental material, sj-pdf-1-cat-10.1177_10760296231213632 for Shell Versus Core Architecture and Biology of Thrombi in Acute Ischemic Stroke: A Systematic Review by Oana Madalina Mereuta, Tamanna Agarwal, Sherief Ghozy, Daying Dai, Santhosh Arul, Waleed Brinjikji, David F. Kallmes and Ram Kadirvel in Clinical and Applied Thrombosis/Hemostasis</p

sj-docx-1-ine-10.1177_15910199231168669 - Supplemental material for The safety profile of single antiplatelet therapy with flow diverters: Systematic review and meta-analysis

Supplemental material, sj-docx-1-ine-10.1177_15910199231168669 for The safety profile of single antiplatelet therapy with flow diverters: Systematic review and meta-analysis by Yigit Can Senol, Atakan Orscelik, Sherief Ghozy, Kobeissi Hassan, Santhosh Arul, Cem Bilgin, Ramanathan Kadirvel and David F Kallmes in Interventional Neuroradiology</p

sj-docx-1-ine-10.1177_15910199231210411 - Supplemental material for Distal versus conventional transradial access for diagnostic cerebral angiography and neurointerventional procedures: A systematic review and meta-analysis

Supplemental material, sj-docx-1-ine-10.1177_15910199231210411 for Distal versus conventional transradial access for diagnostic cerebral angiography and neurointerventional procedures: A systematic review and meta-analysis by Atakan Orscelik, Yigit Can Senol, Hassan Kobeissi, Sherief Ghozy, Cem Bilgin, Santhosh Arul, Ramanathan Kadirvel, Waleed Brinjikji and David F Kallmes in Interventional Neuroradiology</p

sj-docx-1-ine-10.1177_15910199231193925 - Supplemental material for 2b Or 2c-3? A meta-analysis of first pass thrombolysis in cerebral infarction 2b vs multiple pass thrombolysis in cerebral infarction 2c-3 following mechanical thrombectomy for stroke

Supplemental material, sj-docx-1-ine-10.1177_15910199231193925 for 2b Or 2c-3? A meta-analysis of first pass thrombolysis in cerebral infarction 2b vs multiple pass thrombolysis in cerebral infarction 2c-3 following mechanical thrombectomy for stroke by Hassan Kobeissi, Sherief Ghozy, Melika Amoukhteh, Santhosh Arul, Cem Bilgin, Senol Yigit Can, Atakan Orscelik, Mohamed Elfil, Adam Dmytriw, Ramanathan Kadirvel and David F. Kallmes in Interventional Neuroradiology</p

Supplemental Material - Outcomes of mechanical thrombectomy in M1 occlusion patients with or without hyperdense middle cerebral artery sign: A systematic review and meta-analysis

Supplemental Material for Outcomes of mechanical thrombectomy in M1 occlusion patients with or without hyperdense middle cerebral artery sign: A systematic review and meta-analysis by Atakan Orscelik, Yigit Can Senol, Cem Bilgin, Hassan Kobbeisi, Sherief Ghozy, Basel Musmar, Gokce Belge Bilgin, Sara Zandpazandi, Madonna Pakkam, Santhosh Arul, Waleed Brinjikji and David F Kallmes in The Neuroradiology Journal.</p

The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023

The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023</p