886 research outputs found
Optical Feshbach resonances through a molecular dark state: Efficient manipulation of -wave resonances in fermionic Yb atoms
In a recent experiment by Yamazaki {\it et al.} [Phys.Rev. A {\bf 87} 010704
(R) (2013) ], -wave optical Feshbach resonance in fermionic Yb atoms
using purely long-range molecular excited states has been demonstrated. We
theoretically show that, if two purely long range excited states of Yb
are coupled to the ground-state continuum of scattering states with two lasers,
then it is possible to significantly suppress photoassociative atom loss by a
dark resonance in the excited states. We present a general theoretical
framework for creating a dark state in electronically excited molecular
potential for the purpose of increasing the efficiency of an optical Feshbach
resonance. This can be accomplished by properly adjusting the relative
intensity, phase, polarizations and frequency detunings of two lasers. We
present selective numerical results on atom loss spectra, -wave elastic and
inelastic scattering cross sections of Yb atoms to illustrate the
effects of the molecular dark state on optical Feshbach resonance.Comment: 9 pages, 5 figures, Accepted in Phys. Rev.
Tricho-dento-osseous syndrome and precocious eruption
Tricho-dento-osseous syndrome (TDO), an uncommon form of ectodermal dysplasia is an autosomal dominant genetic disorder which is characterized by inherited defects in tissues arising from epithelial-mesenchymal interaction. Genetic studies have revealed that it is caused by mutation in the DLX3 gene. TDO presents with a great phenotypic heterogeneity and studies have suggested that this heterogeneity is the result of environmental factors or other genetic modifiers. In this article, we report a case of TDO in which the child had typical clinical features of hair, teeth and bone defects, as seen in TDO. Parents of the child were unaffected. Genetic analysis of the child revealed mutation in DLX3 gene. The child also showed precocious eruption of the permanent molars, a clinical feature which has been rarely reported. We suggest that the precocious eruption seen in TDO is probably due to a markedly increased osteoblastic activity
Efficient techniques for genotype‐phenotype correlational analysis
BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are sequence variations found in individuals at some specific points in the genomic sequence. As SNPs are highly conserved throughout evolution and within a population, the map of SNPs serves as an excellent genotypic marker. Conventional SNPs analysis mechanisms suffer from large run times, inefficient memory usage, and frequent overestimation. In this paper, we propose efficient, scalable, and reliable algorithms to select a small subset of SNPs from a large set of SNPs which can together be employed to perform phenotypic classification. METHODS: Our algorithms exploit the techniques of gene selection and random projections to identify a meaningful subset of SNPs. To the best of our knowledge, these techniques have not been employed before in the context of genotype‐phenotype correlations. Random projections are used to project the input data into a lower dimensional space (closely preserving distances). Gene selection is then applied on the projected data to identify a subset of the most relevant SNPs. RESULTS: We have compared the performance of our algorithms with one of the currently known best algorithms called Multifactor Dimensionality Reduction (MDR), and Principal Component Analysis (PCA) technique. Experimental results demonstrate that our algorithms are superior in terms of accuracy as well as run time. CONCLUSIONS: In our proposed techniques, random projection is used to map data from a high dimensional space to a lower dimensional space, and thus overcomes the curse of dimensionality problem. From this space of reduced dimension, we select the best subset of attributes. It is a unique mechanism in the domain of SNPs analysis, and to the best of our knowledge it is not employed before. As revealed by our experimental results, our proposed techniques offer the potential of high accuracies while keeping the run times low
Delivering categorized news items using RSS feeds and web services
In the past decade the massive growth of the Internet brought huge changes in the way humans live their daily life; however, the biggest concern with rapid growth of digital information is how to efficiently manage and filter unwanted data. In this paper, we propose a method for managing RSS feeds from various news websites. A Web service was developed to provide filtered news items extracted from RSS feeds and these were categorized based on classical text categorization algorithms. A client application consuming this Web service retrieves and displays such filtered information. A prototype was implemented using Rapidminer 4.3 as a data mining tool and SVM as a classification algorithm. Experimental results suggest that the proposed method is effective and saves a significant amount of user processing time.<br /
Cu(I)/Cu(II) templated functional pseudorotaxanes and rotaxanes
Threaded complexes like pseudorotaxanes, rotaxanes based on Cu(I)/Cu(II) ions have shown to be promising for the construction of mechanically interlocked molecular-level architectures. In this short review, we focus on the synthetic strategies developed to construct pseudorotaxanes and rotaxanes using Cu(I)/Cu(II) ions as template. Further, brief discussions on chemical and mechanical properties associated with some of the selected to Cu(I)/Cu(II) based pseudorotaxanes and rotaxanes are presented
Strategic integration decision under supply chain competition in the presence of online channel
This study explores the pricing decisions of substitutable products for two competing supply chains in the presence of an online channel. Each supply chain consisting of a single manufacturer and an exclusive retailer and one of the manufacturers distributes products through the online channel. We examine optimal decisions under five scenarios to explore how the strategic cooperation between two manufacturers at the upstream horizontal level or with the retailer at the vertical level affects product pricing decisions and the performance of two supply chains? The results reveal that decisions for cooperation with competing manufacturers and opening an online channel are correlated. In the absence of an online channel, cooperation with their respective retailer can lead to a higher supply chain profit. However, if a manufacturer opens an online channel, then cooperation with competing manufacturers can lead to a higher supply chain profit. Under the vertical integration, total supply chain profit might be lower compared to a scenario where members in each supply chain remain independent. Consumers also need to pay more for products
Transfer of chromium from environment to fish in East Kolkata wetlands – evaluation by structural equation modeling
Chromium (Cr) is a significant pollutant in the effluents from leather industries and domestic city sewage. Cr was determined in water, sediment, and different tissues (gill, muscle, intestine, liver, and kidney) of Nile tilapia, Oreochromis niloticus harvested from wastewater-fed aquaculture (WFA) situated at Bamonghata, Bantala, Chowbaga and Chingrighata of East Kolkata Wetlands (EKW), a Ramsar site in West Bengal, India. The results showed that Cr concentration in surface water ranged between 0.05 to 0.15 mg/L, while Cr was detected at high concentration (100–300 mg/kg) in the sediment soil of the first three WFAs and in moderate concentration (50–110 mg/kg) in Chingrighata WFA. Average Cr concentrations in the tissues were ranked in the following sequence: kidney>liver>intestine>gill>muscle. However, the extent of accumulation of Cr in different tissues varied between the WFAs. We used Structural Equation Modeling (SEM) to determine the route of Cr transfer. The fitness of the model was evaluated by the performance measures. Cr accumulation pathways varied between the sites depending upon the level of Cr in water or sediment. Except for Bamonghata WFA, sediment was found as the principal source of accumulation of Cr in different tissues of O. niloticus. Cr refluxed from sediment into overlying water and accumulated in fish either through the food chain or through direct accumulation from water. In Bamonghata WFA, the role of sediment in the transfer of Cr could not be established due to the high water depth or biological non-availability of Cr in the sediment. It is concluded from this study that fish reared in the WFAs of EKW are still not hazardous in respect to Cr but require proper management to avoid the influx of Cr-containing effluents into the WFAs. Graphical abstract: [Figure not available: see fulltext.].</p
Epidemiology Of Gastrointestinal Parasites In Livestock Of Cooch Behar District, India
Livestock rearing, particularly cattle, sheep, and goats, forms a significant backbone of the rural economy in India. Gastrointestinal (GI) parasitic infections pose a substantial economic burden due to reduced productivity, compromised health, and increased mortality in livestock. While studies exist on the prevalence of GI parasites in these animals across India, information from the Cooch Behar district of North Bengal is lacking. This study aimed to investigate the prevalence and burden of GI parasites in cattle, goats, and sheep from Cooch Behar district. A total of 412 fecal samples (148 cattle, 124 goats, and 140 sheep) were collected from January to December 2019 and examined using standard parasitological techniques. The overall prevalence of GI parasites was alarmingly high: 72.97% in cattle, 76.61% in goats, and 67.85% in sheep. No significant difference was observed in prevalence between the three livestock species (p > 0.05). However, a significant seasonal effect (p < 0.05) was identified, with the highest prevalence and intensity of infection observed during the rainy season, followed by summer and winter. Eimeria spp. (coccidia) and Strongyloides spp. (nematodes) were the most prevalent parasites identified, followed by Trichostrongylus spp., Fasciola spp., Bunostomum spp., Nematodirus spp., Moniezia spp., Paramphistomum spp., Oxyuris spp., and Trichuris spp. These findings highlight the critical need for strategic deworming programs, improved hygiene practices, and further research on the impact of these parasites on livestock health and productivity in the Cooch Behar distric
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