sj-docx-2-tar-10.1177_17534666231214134 – Supplemental material for Nebulization versus metered-dose inhaler and spacer in bronchodilator responsiveness testing: a retrospective study

Supplemental material, sj-docx-2-tar-10.1177_17534666231214134 for Nebulization versus metered-dose inhaler and spacer in bronchodilator responsiveness testing: a retrospective study by Rongli Lu, Ying Li, Chengping Hu, Pinhua Pan, Qiaohong Zhao and Ruoxi He in Therapeutic Advances in Respiratory Disease</p

sj-docx-1-tar-10.1177_17534666231214134 – Supplemental material for Nebulization versus metered-dose inhaler and spacer in bronchodilator responsiveness testing: a retrospective study

Supplemental material, sj-docx-1-tar-10.1177_17534666231214134 for Nebulization versus metered-dose inhaler and spacer in bronchodilator responsiveness testing: a retrospective study by Rongli Lu, Ying Li, Chengping Hu, Pinhua Pan, Qiaohong Zhao and Ruoxi He in Therapeutic Advances in Respiratory Disease</p

Diagnostic Accuracy of Bronchodilator Response for Asthma in a Population of South China

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Table_1_A scoring system based on novel biomarkers and clinical risk factors to predict invasive candidiasis in immunocompetent critically ill patients.DOCX

BackgroundDelayed diagnosis further increases the mortality of invasive candidiasis (IC) in intensive care unit (ICU) patients. This study aimed to develop and validate a score based on novel serological biomarkers and clinical risk factors for predicting IC in immunocompetent ICU patients.MethodsWe retrospectively collected clinical data and novel serological markers on admission to ICU. Multivariate logistic regression was used to identify the risk factors associated with IC, which were adopted to establish a scoring system.ResultsPatients with IC had a higher C-reactive protein-to-albumin ratio (CAR) and neutrophil-to-lymphocyte ratio (NLR) and lower prognostic nutritional index than those without IC. The NLR, CAR, sepsis, total parenteral nutrition, 1,3-β-D-glucan (BDG)-positivity, and Sequential Organ Failure Assessment score were identified as independent risk factors for IC by multivariate logistic regression analysis and entered into the final scoring system. The area under receiver operating characteristic curve of the score were 0.883 and 0.892, respectively, in the development and validation cohort, higher than Candida score (0.883 vs.0.730, p ConclusionWe established a parsimonious score based on NLR, CAR, BDG-positivity, and clinical risk factors, which can accurately identify IC in ICU patients to give treatment on time and reduce mortality.</p

Additional file 2 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Additional file 2. Table S2: Comparison of daily duration of treatment with 7days after randomization, the time of treatment failure and noninvasive positive pressure ventilation start between the conventional oxygen therapy group and the high-flow nasal cannula group

Additional file 4 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Additional file 4. Figure S1: Kaplan-Meier analysis of time since intervention to readmission during 90 days follow-up period. The cumulative incidence function and Gray’s test were used to consider deaths as competing events to evaluate the difference of time to readmission for acute exacerbation between two groups

Additional file 3 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Additional file 3. Table S3: The comparison of age, gender, oxygenation and blood gas parameters on admission between the enrolled patients and the declined patients

Additional file 1 of High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Additional file 1. Table S1: Settings of treatment, vital sign, Borg scores, airway dryness score and blood gas analysis between the conventional oxygen therapy group and the high-flow nasal cannula group within 72 hours after randomization