23 research outputs found

    Demographic and clinical characteristics of 96 patients randomized to treatment of Azithromycin (nβ€Š=β€Š50) or placebo (nβ€Š=β€Š46) and by ethnicity.

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    <p><b>Median and IQR (25–75) for continuous variables. Actual numbers for categorical variables and percentages.</b></p><p><b>NB</b>: Missing variables described.</p><p><b>Azithromycin</b>: Gestational age β€Š=β€Š3 (6%). Birth weight β€Š=β€Š6 (12%). Mother smoked during pregnancy β€Š=β€Š3 (6%). Exposure to household smoke β€Š=β€Š2 (4%), <b>Placebo</b>: Gestational age: β€Š=β€Š2 (4%). Birth weight β€Š=β€Š3 (6.5%).</p><p><b>Indigenous children</b>: Gestational age β€Š=β€Š2 (3.3%). Birth weight β€Š=β€Š4 (6.5%). Mother smoked during pregnancy β€Š=β€Š2 (3%). Exposure to household smoke β€Š=β€Š1 (1.6%): <b>Non Indigenous children</b>: Gestational age: β€Š=β€Š3 (8.6%). Birth weight β€Š=β€Š5 (14.3%) Mother smoked during pregnancy β€Š=β€Š1 (3%). Exposure to household smoke β€Š=β€Š1 (3%).</p

    Antibiotic resistance (proportion of carriers) in respiratory bacteria from Australian and Alaskan children at baseline and end of study.

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    *<p>P&lt;0.05, ** P&lt;0.01 for difference in resistance between Australian and Alaskan carriers; CI, confidence interval.</p>1<p>MacR, macrolide-resistant: azithromycin (Australia) and erythromycin (Alaska) minimum inhibitory concentration (MIC) &gt;0.5 mg/L.</p>2<p>AziIR, azithromycin intermediate resistant: MIC &gt;0.12–4 mg/L; AziR, azithromycin resistant: MIC &gt;4 mg/L for Australian children.</p>3<p>All isolates from Alaskan children were susceptible on disk diffusion; MICs were not determined.</p>4<p>Isolates from one swab did not grow on sensitivity plates.</p>5<p>EryR, erythromycin resistant on disk diffusion.</p>6<p>PenIR, penicillin intermediate resistant: MIC &gt;0.06–2 mg/L; no resistant (MIC &gt;2 mg/L) isolates were detected in either cohort.</p>7<p>AmpR, ampicillin MIC &gt;1 mg/L.</p>8<p>BLpos, beta-lactamase positive.</p>9<p>MethR, methicillin resistant on disk diffusion.</p