1,938 research outputs found
Efficiency of Horizontal and Vertical Well Patterns on the Performance of Micellar-Polymer Flooding in Anisotropic Reservoirs
There is increasing interest in micellar-polymer flooding because of the need to increase oil production from depleted and waterflooded reservoirs. Using horizontal wells for injection and production in a micellar-polymer flood process, higher sweep efficiency is expected compared with the use of conventional patterns by vertical wells. However, the use of horizontal wells is very sensitive to the well pattern designed to operate the process. This paper presents an analysis of how the overall performance of a micellar-polymer flood process in anisotropic reservoirs is influenced by the well pattern using horizontal injector and producer in different configurations. A three-dimensional numerical simulator for fluid flow and mass transport is used to analyze the effectiveness of well combinations in micellar-polymer applications. The potential for a horizontal well application was assessed through different situations in combinations of injection and production wells and degree of reservoir anisotropy. Results from the study have demonstrated that significant amount of oil can be recovered additionally and injectivity was remarkably improved by utilizing a combination of horizontal wells. The improvement of injectivity through a horizontal injection well was higher when it was combined with horizontal producer parallel to the injector. The overall performances in anisotropic reservoirs strongly depend on the type of wells considered and the orientation of the horizontal wells with respect to the permeability directions. Combination of horizontal wells placed parallel to the low permeability direction yields the best performance. In high permeability ratio reservoirs, the presence of horizontal injectors is more significant in defining the efficiency of the micellar-polymer flood than the horizontal producers.Key words: Micellar-polymer flood; Horizontal well; Anisotropy; Injectivit
Screening Effects on Nonrelativistic Bremsstrahlung in the Scattering of Electrons by Neutral Atoms
Atomic screening effects on nonrelativistic electron-atom bremsstrahlung radiation are investigated using a simple analytic solution of the Thomas-Fermi model for many-electron atoms. The Born approximation is assumed for the initial and final states of the projectile electron. The results show that the screening effect is important in the soft radiation region and is decreasing with increasing radiation. These results help provide correct information about the behavior of bound electrons in the target atom in bremsstrahlung processes
Simulation Study on Miscibility Effect of CO 2
The minimum miscibility pressure (MMP) determines the main mechanism of CO2 flooding, which is either an immiscible or miscible process. This paper examines the recovery improvements of CO2 flooding in terms of both the injection temperature and solvent composition. The results show that a lower temperature injection and LPG (liquefied petroleum gas) mixture can considerably improve oil recovery due to the reduced MMP in the swept area caused by the injected solvent. For the pure CO2 injection at the reservoir temperature, oil recovery is 59% after 1.0 PV CO2 injection. The oil recoveries by CO2-LPG mixtures are improved to 73% with 0.1 mole fractions of LPG and 81% with 0.2 mole fractions of LPG. The recovery factor from low-temperature CO2 injection is 78%, which is 32% higher compared to the isothermal case. The recoveries obtained by low-temperature CO2-LPG injection increase up to 87% of the initial oil. Heat transfer between the reservoir and the formation of over/underburden should be considered in order to describe the process more accurately. Additionally, the recovery factors from the heat transfer models are decreased by 4–12% in comparison with the original nonisothermal models
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Understanding the catalytic chemisorption of the cyanogen chloride via breakthrough curve and genetic algorithm
This study investigated the catalytic chemisorption of cyanogen chloride(CK) with a metal(ASZM) – triethylenediamine(TEDA) complex. XPS data, IR spectra, and DFT calculations demonstrated that the synergetic catalytic hydrolysis of CK by ASZM-TEDA is kinetically favorable, with the enhanced reactivity of water on the catalyst as the primary cause for the accelerated catalytic hydrolysis. To validate the results, ASZM-TEDA was impregnated into activated carbon beads to form a packed-bed reactor for this breakthrough experiment. The proposed species-transport equation parameters were fitted using the genetic algorithm, and the correlation between parameters was compared. The study concludes that TEDA can affect the diffusivity for overall mass transfer-related reactions and accelerate the catalytic reaction of metal with CK. This study is the first to describe chemisorbed breakthrough with catalyst reaction in-depth and provides insights into the optimized ratio between TEDA and metal complexes. This methodology can be applied to various breakthrough experiments with chemical reactions
Comparison of MRI features and surgical outcome among the subtypes of focal cortical dysplasia
AbstractPurposeFocal cortical dysplasia (FCD) is the most common pathological diagnosis in patients who have undergone surgical treatment for intractable neocortical epilepsy. However, presurgical identification of MRI abnormalities in FCD patients remains difficult, and there are no highly sensitive imaging parameters available that can reliably differentiate among FCD subtypes. The purpose of our study was to investigate the surgical outcome in FCD patients with identifiable MRI abnormalities and to evaluate the prognostic role of the various MRI features and the characteristics of FCD pathology.MethodsWe retrospectively recruited epilepsy patients who had undergone surgical treatment for refractory epilepsy with focal MRI abnormalities and the pathological diagnosis of FCD. We evaluated the surgical outcome according to the pathological subtypes, and studied the prognostic roles of various MRI features. We used recently proposed three-tiered FCD classification system which included FCD type III when FCD occurs in association with other potentially epileptogenic pathologies.ResultsA total of 69 patients were included, and 68.1% of patients became seizure free. Patients with FCD type III had a lower chance for achieving seizure freedom (7/15) than in patients with isolated FCD (FCD types I and II) (40/54, p=0.044). Cortical thickness and blurring of gray–white matter junction were more common in isolated FCD than in FCD type III, but most MRI features failed to differentiate between FCD types I and II, and only the transmantle sign was specific for FCD type II. We failed to find a prognostic value of specific MRI abnormalities of prognostic value in terms of post-epilepsy surgery outcome in FCD patients.ConclusionsOur study showed that patients with FCD III have poor surgical outcome. Typical MRI features of isolated FCD such as cortical thickness and blurring of gray–white matter junction were less common in FCD type III and only transmantle sign was helpful in differentiating between FCD types I and II
Chronic social stress in early life can predispose mice to antisocial maltreating behavior
Purpose In our previous study, we developed an assay system to evaluate antisocial maltreating behavior of conspecific mice using a perpetrator–victim paradigm. We also generated a mouse model for the maltreating behavior by mimicking child maltreatment or abuse. Here, we further investigate the antisocial behavior using anti-aggressive and antipsychotic drugs. Methods Model mice sequentially subjected to maternal separation (MS), social defeat (SD), and social isolation (SI) in that order (MS/SD/SI model) were subjected to a maltreating behavioral task. The MS/SD/SI mice were treated with oxytocin (OXY), clozapine (CLZ), haloperidol (HAL), and 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Western blotting and enzyme-linked immunosorbent assay were used for protein analysis. Results A substantial portion of the MS/SD/SI model mice (46% of males and 40% of females) showed a higher number of nose pokes than the control. OXY or 8-OH-DPAT treatment reduced the high number of nose pokes by the MS/SD/SI mice, whereas HAL increased it. CLZ did not affect the number of nose pokes by the MS/SD/SI mice. Interestingly, although the OXY level in the MS/SD/SI mice was similar to that in the control, the amount of OXY receptor was lower in the MS/SD/SI mice. The amount of 5-HT1A receptor was also decreased in the MS/SD/SI mice. Conclusion Chronic social stress in childhood might predispose a mouse to antisocial behavior. Our maltreating behavior assay system, including the MS/SD/SI model, is a good animal system for research on and drug screening for brain disorders associated with antisocial or psychotic behavior
Frontal lobe epilepsy: Clinical characteristics, surgical outcomes and diagnostic modalities
SummaryObjectiveTo identify surgical prognostic factors and to characterize clinical features according to the location of the intracranial ictal onset zone of frontal lobe epilepsy (FLE) in order to assess the role of various diagnostic modalities, including concordances with presurgical evaluations.MethodsWe studied 71 FLE patients who underwent epilepsy surgery and whose outcomes were followed for more than 2 years. Diagnoses were established by standard presurgical evaluation.ResultsClinical manifestations could be categorized into six types: initial focal motor (9 patients), initial versive seizure (15), frontal lobe complex partial seizure (14), complex partial seizure mimicking temporal lobe epilepsy (18), initial tonic elevation of arms (11), and sudden secondary generalized tonic–clonic seizure (4). Thirty-seven patients became seizure-free after surgery. Five patients were deleted in the analysis because of incomplete resection of ictal onset zones. The positive predictive value of interictal EEG, ictal EEG, MRI, PET, and ictal SPECT, respectively were 62.5%, 56.4%, 73.9%, 63.2%, and 63.6%, and the negative predictive value were 46.0%, 44.4%, 53.5%, 44.7%, and 51.7%. No significant relationship was found between the diagnostic accuracy of these modalities and surgical outcome, with the exception of MRI (p=0.029). Significant concordance of two or more modalities was observed in patients who became seizure-free (p=0.011). We could not find any clinical characteristic related to surgical outcome besides seizure frequency. No definite relationship was found between the location of intracranial ictal onset zone and clinical semiology.ConclusionAlthough various diagnostic methods can be useful in the diagnosis of FLE, only MRI can predict surgical outcome. Concordance between presurgical evaluations indicates a better surgical outcome
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