52 research outputs found
Preoperative atrial fibrillation in patients undergoing cardiac surgery: Gender versus other factors. Authors’ reply
Differences in Health Approaches between Generation Z and Generation X
The aim of this article is to analyze the differences in health approaches between Generation Z (born after 1995) and Generation X (born between 1965 and 1980). Research conducted after 2018 indicates that lifestyle, priorities, and health habits significantly differ between these age groups, stemming from distinct cultural experiences and technological advancements. The article is based on a review of scientific publications discussing issues related to physical activity, diet, mental health, and the use of technology in health care. The findings suggest that Generation Z shows greater engagement with health technologies, while Generation X prefers traditional health maintenance methods. The conclusions drawn from this analysis are crucial for health policymakers, educators, and the medical sector
Noise and Light Exposure and Cardiovascular Outcomes: A Review of Evidence, Potential Mechanisms and Implications
Cardiovascular diseases (CVD) are the leading cause of global non-communicable disease-related deaths. In recent years there has been increasing discussion about the influence of environmental risk factors, including noise and light, on the occurrence and course of these conditions. Recent studies highlight the impact of road traffic noise on an elevated risk of stroke and increased mortality in the course of coronary artery disease (CAD). In the case of threats arising from light pollution, there are more limited published studies; however, these show an increased hospitalization risk associated with CAD. Existing analyses cannot dismiss these environmental factors, highlighting the need for further research. Future studies should investigate not only road traffic noise but also consider railway and aircraft noise. Additionally, research on light pollution should include younger individuals too. In the future, incorporating individual assessments of noise and light pollution exposure, along with the identification of particularly vulnerable groups, could contribute to refining methods of individual risk stratification and implementing new preventive strategies.</p
Excessive Body Weight as a Determinant of Quality of Life
Introduction and objective. This article aims to discuss the issue of excessive body weight based on available literature. It highlights the physical and psychosocial consequences of obesity and addresses the topic of weight reduction.
Review methods. Bibliographic material was retrieved from PubMed and Google Scholar using terms related to obesity, overweight, and quality of life. Forty-six articles published between 2015 and 2024 were selected.
Conclusions. Obesity is a source of numerous somatic and psychosocial complications. The article shows the negative impact of these consequences on quality of life. One of the main goals of obesity treatment is to improve quality of life. Therefore, the article describes manner to reduce body weight, sources of motivation and adversity on the treatment path and explores the topic of psychological support in obesity treatment
The Hormonal dysregulation and its consequences in Obese Women - overview
Introduction
Obesity, a global health challenge, significantly impacts women's hormonal balance, affecting metabolic and reproductive health. Defined as a BMI >30 kg/m² by WHO, its prevalence is rising, creating substantial health and economic challenges.
Aim of Study
This study explores the effects of obesity on women's hormonal regulation, emphasizing associated conditions like PCOS, insulin resistance, infertility, and cardiometabolic diseases, while identifying mechanisms and potential interventions.
Material and Methods
A review of 34 peer-reviewed articles (2000–2024) using PRISMA criteria analyzed hormonal imbalances caused by obesity, focusing on adipokines such as leptin and adiponectin, and their roles in glucose metabolism, lipid regulation, and inflammation.
Analysis of Literature
Obesity-induced chronic inflammation disrupts insulin regulation, sex hormones, and the hypothalamic-pituitary-adrenal axis. It causes ovulatory disorders, reduced oocyte quality, and impaired endometrial receptivity. Mechanisms like insulin resistance, hyperandrogenism, and leptin dysfunction are central to these effects.
Conclusion
A multidimensional treatment approach, including lifestyle changes, pharmacotherapy (e.g., GLP-1 agonists), and surgical interventions, is essential. Personalized strategies can alleviate symptoms, improve metabolic and reproductive outcomes, and enhance quality of life for women with obesity
Magnesium Homeostasis and Implications for Human Health: A Review of the Literature
Magnesium ions (Mg²⁺) is a vital ion for human health, involved in numerous bodily functions, including energy production and protein synthesis. Despite its significance, serum magnesium levels are often overlooked in clinical settings, even though they can be disrupted in various health conditions. This review delves into the role of magnesium in human health and disease, highlighting its importance in key organs like the brain, heart, and muscles. Magnesium supplementation has shown promise in treating conditions such as migraine, depression, heart disease, and asthma. Recent discoveries have unveiled genetic factors, including mutations in specific genes, that can lead to magnesium deficiency. Additionally, certain medications, such as diuretics and proton pump inhibitors, can contribute to low magnesium levels. This review explores the mechanisms of magnesium regulation in the intestines, kidneys, and bones
Applications of MDMA in Modern Medicine - A Literature Review
MDMA or 3,4- methylenedioxymethamphetamine is a psychoactive substance, exhibiting mild hallucinogenic properties, that became widely known as a recreational party drug. However, its ability in helping individuals access deeply rooted emotions has prompted significant interest in its potential applications within clinical practice. MDMA’s mechanism of action involves increasing the release of serotonin, dopamine and oxytocin. This process enhances neuroplasticity, fosters empathy and aids in trauma processing and fear extinction. This study aims to explore the potential uses of MDMA in medicine, particularly in treating mental illnesses. The article was developed using data from the „PubMed” and „Google Scholar” databases, with particular emphasis on articles published after 2021. When combined with psychotherapy, MDMA offers significant therapeutic benefits, especially for patients resistant to conventional treatments. Existing research primarily highlights its effectiveness in managing post traumatic stress disorder (PTSD) and anxiety disorders, with emerging evidence suggesting potential benefits for conditions like depression and eating disorder. While recreational use of MDMA poses risks, its use in a controlled environment demonstrates a favourable safety profile. Despite the highly promising results of MDMA- assisted therapy so far, additional clinical research is crucial to enable this drug to revolutionise future treatment methods
The Impact of Anesthetic Modality Selection on Surgical Outcomes in Trauma Management
The selection of anesthesia during surgical management of injuries is of paramount importance in ensuring patient comfort, procedural safety, and optimal surgical outcomes. The determination of the anesthetic modality is made by the anesthesiologist in consultation with the surgical team, taking into consideration the patient's medical status, the nature and extent of the injury, the anticipated duration of the procedure, and, when feasible, the patient’s preferences
The Role of Vitamin D in the Pathomechanism of Inflammatory Bowel Disease (IBD) and its Therapeutic Implications - a literature review
Introduction: Vitamin D holds a crucial role in the pathogenesis of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC). Its mechanisms of action involve immune system modulation, specifically by reducing the production of pro-inflammatory cytokines, such as IL-6 and TNF-α, while enhancing the levels of anti-inflammatory cytokines, such as IL-10. Furthermore, vitamin D contributes to the maintenance of intestinal barrier integrity by strengthening epithelial tight junctions. It also exerts a beneficial influence on the intestinal microbiota, promoting the proliferation of beneficial bacterial species, such as Faecalibacterium prausnitzii, which play a role in mitigating disease relapses and sustaining immune homeostasis. Although vitamin D supplementation demonstrates potential in reducing inflammation and improving clinical outcomes, the observed effects remain varied and require further investigation.
Aim: The purpose of this study was to analyze the mechanisms of action of vitamin D in the context of the pathogenesis of inflammatory bowel disease (IBD) and its potential therapeutic applications, with particular emphasis on clinical studies evaluating vitamin D supplementation
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