sj-docx-1-cix-10.1177_11769351231168006 – Supplemental material for Quantifying the Contributions of Environmental Factors to Prostate Cancer and Detecting Risk-Related Diet Metrics and Racial Disparities

Supplemental material, sj-docx-1-cix-10.1177_11769351231168006 for Quantifying the Contributions of Environmental Factors to Prostate Cancer and Detecting Risk-Related Diet Metrics and Racial Disparities by Wensheng Zhang and Kun Zhang in Cancer Informatics</p

Site-Selective, Low-Loading, Au Nanoparticle–Polyaniline Hybrid Coatings with Enhanced Corrosion Resistance and Conductivity for Fuel Cells

Ultralow loading of Au nanoparticles (0.038 mg cm^–2) and a polyaniline hybrid coating (AuNP-PANI) were deposited on stainless steel (SS316L) coupons. The unique two-step approach utilizing electrochemical deposition via cyclic voltammetry enabled growth of AuNPs in the fibrous PANI micropores thereby achieving enhanced surface coverage of SS316L and minimizing substrate corrosion via blocking of pores. The hybrid coatings revealed significantly low interfacial contact resistance values of 16.6 mΩ cm² (achieving the US DOE 2017 targets). Potentiodynamic tests revealed the excellent corrosion resistance of AuNP-PANI hybrid coatings with a corrosion potential of 0.61 V_SHE, which is positively shifted by 790 and 390 mV as compared to bare SS316L and PANI-SS316L, respectively. The corresponding potentiostatic corrosion current density of AuNP-PANI was reduced to 0.63 μA/cm² from 2.28 and 0.65 μA/cm² for bare SS316L and PANI-SS316L samples, respectively, thereby providing excellent stability in the cathodic polymer electrolyte fuel cell (PEFC) environment. Extensive electron microscopy and X-ray diffraction studies showed uniformly placed AuNP bundles with an average cluster size of 16 nm with Au (200) as the most prominent crystallite phase. Thermogravimetric studies revealed that the AuNPs did not affect the thermal stability of PANI which remained stable up to 260 °C which is well above the operating temperature of conventional PEFCs, making them highly suitable for coatings on bipolar plates for enhanced conductivity and corrosion resistance

Direct Wet-Spun Single-Walled Carbon Nanotubes-Based <i>p–n</i> Segmented Filaments toward Wearable Thermoelectric Textiles

Three-dimensional thermoelectric (TE) textiles (TETs) fabricated with TE filaments (TEFs) possess merits over other types such as thickness–direction thermal energy harvesting and excellent conformability with dynamic body curves, revealing the prospect of generating electricity for on-body application. Nonetheless, there is still a lack of a costless but scalable method to automatically and seamlessly produce in-series interconnected p–n segmented TEFs with high TE properties via conventional fiber spinning processes. Here, we developed an alternate wet-spinning strategy to continuously manufacture single-walled carbon nanotube-based p–n segmented TEFs at large scale. The TEF with high electrical conductivity (400–800 S cm–1) displays a low contact resistivity of 189.8 μΩ cm2 between the segments and interelectrode, showing 2 orders of magnitude smaller than that reported in the literature. More importantly, the power factors of p-type and n-type segments are 26.25 and 17.14 μW m–1 K–2, respectively, which are 3 and 4 orders of magnitude higher than those of advanced studies. We finally embroidered it into spacer fabric to fabricate a wearable TET, demonstrating an output power density of 501 nW m–2 at ΔT = 27.7 K. The methodology can inspire the development of fiber-based electronics such as wearable TEs and diodes and so forth

Direct Wet-Spun Single-Walled Carbon Nanotubes-Based <i>p–n</i> Segmented Filaments toward Wearable Thermoelectric Textiles

Three-dimensional thermoelectric (TE) textiles (TETs) fabricated with TE filaments (TEFs) possess merits over other types such as thickness–direction thermal energy harvesting and excellent conformability with dynamic body curves, revealing the prospect of generating electricity for on-body application. Nonetheless, there is still a lack of a costless but scalable method to automatically and seamlessly produce in-series interconnected p–n segmented TEFs with high TE properties via conventional fiber spinning processes. Here, we developed an alternate wet-spinning strategy to continuously manufacture single-walled carbon nanotube-based p–n segmented TEFs at large scale. The TEF with high electrical conductivity (400–800 S cm–1) displays a low contact resistivity of 189.8 μΩ cm2 between the segments and interelectrode, showing 2 orders of magnitude smaller than that reported in the literature. More importantly, the power factors of p-type and n-type segments are 26.25 and 17.14 μW m–1 K–2, respectively, which are 3 and 4 orders of magnitude higher than those of advanced studies. We finally embroidered it into spacer fabric to fabricate a wearable TET, demonstrating an output power density of 501 nW m–2 at ΔT = 27.7 K. The methodology can inspire the development of fiber-based electronics such as wearable TEs and diodes and so forth

Data for: In silico unravelling pathogen-host signaling cross-talks via pathogen mimicry and human protein-protein interaction networks

Supplimentary file

Legislative Documents

Also, variously referred to as: Senate bills; Senate documents; Senate legislative documents; legislative documents; and General Court documents

Synthesis of sevoflurane loaded reduced graphene oxide nanoparticles system for neuroprotective effects for preconditioning against focal cerebral ischaemia

In this study, sevoflurane (SF) loaded, Fas ligand conjugated reduced graphene oxide (rGO) system is fabricated as a therapeutic agent to target brain ischaemic region. The fluorescence investigation of mice brain denoted that the encapsulated SF in rGOs adsorbed with Fas ligand antibody could be significantly distributed to the ipsilateral side of the ischaemic brain. In addition, the immune-histochemical assay presented that the specific nanoparticles especially deposited in the ischaemic part of the tested mice model. Furthermore, SF encapsulated rGO system exhibited noticeable progress in the brain damage along with neurological deficit post ischaemia with limited dosages in contrast to regular SF. Additionally, Rhodamine labelled nanoparticles were used to find whether Fas ligand antibody has the ability to lead the SF-encapsulated nano rGO to enter the ischaemic part of brain as well as carry out neuro-protection. Overall, these experimental findings suggested that rGOs conjugated Fas ligand system could be treated as an ideal brain targeting drug for cerebral ischemia.</p

Heterogeneity analysis of enterprise ownership and industry categories.

Heterogeneity analysis of enterprise ownership and industry categories.</p

Co-occurrence picture of EPU from 2000 to 2021.

Note: The figure is similar but not identical to the original image and is therefore for illustrative purposes only.</p

Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish (<i>Danio rerio</i>) at Low Concentrations

Synthetic corticosteroids may pose an environmental risk to fish. Here, we describe multiend point responses of adult zebrafish (8 months old) upon 21-day exposure to a commonly prescribed corticosteroid, fludrocortisone acetate (FLU), at concentrations between 0.006 and 42 μg/L. No remarkable reproductive impacts were observed, while physiological effects, including plasma glucose level and blood leukocyte numbers were significant altered even at 42 ng/L. Ovary parameters and transcriptional analysis of hypothalamic–pituitary–gonadal–liver axis revealed negligible effects. Significant alterations of the circadian rhythm network were observed in the zebrafish brain. Transcripts of several biomarker genes, including per1a and nr1d1, displayed strong transcriptional changes, which occurred at environmental relevant concentrations of 6 and 42 ng/L FLU. Importantly, the development and behavior of F1 embryos were significant changed. Heartbeat, hatching success and swimming behavior of F1 embryos were all increased even at 6 and 42 ng/L. All effects were further confirmed by exposure of eleuthero-embryos. Significant transcriptional changes of biomarker genes involved in gluconeogenesis, immune response and circadian rhythm in eleuthero-embryos confirmed the observations in adult fish. Hatching success, heartbeat, and swimming activity were increased at 81 ng/L and higher, as with F1 embryos. These results provide novel insights into the understanding of potential environmental risks of corticosteroids