319 research outputs found

    sj-jpg-2-pie-10.1177_09544089231160493 - Supplemental material for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor

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    Supplemental material, sj-jpg-2-pie-10.1177_09544089231160493 for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor by Jun Xiao and Maofei Geng in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p

    sj-xlsx-3-pie-10.1177_09544089231160493 - Supplemental material for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor

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    Supplemental material, sj-xlsx-3-pie-10.1177_09544089231160493 for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor by Jun Xiao and Maofei Geng in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p

    sj-jpg-1-pie-10.1177_09544089231160493 - Supplemental material for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor

    No full text
    Supplemental material, sj-jpg-1-pie-10.1177_09544089231160493 for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor by Jun Xiao and Maofei Geng in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p

    sj-xlsx-5-pie-10.1177_09544089231160493 - Supplemental material for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor

    No full text
    Supplemental material, sj-xlsx-5-pie-10.1177_09544089231160493 for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor by Jun Xiao and Maofei Geng in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p

    sj-xlsx-4-pie-10.1177_09544089231160493 - Supplemental material for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor

    No full text
    Supplemental material, sj-xlsx-4-pie-10.1177_09544089231160493 for Analysis and treatment of gas pulsation in the pipeline of a hyper compressor by Jun Xiao and Maofei Geng in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p

    Table1_Comprehensive Analysis of the Aberrance and Functional Significance of Ferroptosis in Gastric Cancer.XLSX

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    Objective: Ferroptosis is a type of iron-dependent necrosis related to cancer. Nevertheless, the features of ferroptosis in gastric cancer (GC) remain poorly understood. This study conducted a systematic analysis of ferroptosis regulators in GC.Methods: We gathered five GC cohorts, namely, TCGA-STAD, GSE84437, GSE62254, GSE26901, and GSE15459. Unsupervised clustering analysis was adopted to cluster GC patients into different ferroptosis subtypes based on ferroptosis regulators. Immune cell infiltration and hallmark pathway activity were estimated via ssGSEA. The ferroptosis index was developed with the PCA computational method. Response to chemotherapy agents and small molecular compounds was inferred via GDSC, CTRP, and PRISM projects. Two anti-PD-1 therapy cohorts were gathered and the potential of FPI in predicting immune response was assessed.Results: Expression profiles, genetic mutations, DNA methylation, prognostic implications, and drug sensitivity of ferroptosis regulators were characterized in GC. Three ferroptosis subtypes were clustered with distinct prognosis, hallmark pathway activity, and tumor-infiltrating immune cells. Ferroptosis levels were quantified based on the expression of prognostic ferroptosis-related signatures. The significant relationships between FPI and clinicopathological characteristics were observed. Furthermore, high FPI was in relation to poor prognosis, inflamed tumor microenvironment (TME) as well as high sensitivity to chemotherapy agents (docetaxel and cisplatin), and CTRP- and PRISM-derived compounds. Also, FPI acted as a promising predictor of immune response.Conclusion: Collectively, our findings identified a novel ferroptosis-based subtype classification of GC, and revealed the potential of ferroptosis in forming TME diversity and complexity, and guiding individualized treatment.</p

    Table3_Comprehensive Analysis of the Aberrance and Functional Significance of Ferroptosis in Gastric Cancer.XLSX

    No full text
    Objective: Ferroptosis is a type of iron-dependent necrosis related to cancer. Nevertheless, the features of ferroptosis in gastric cancer (GC) remain poorly understood. This study conducted a systematic analysis of ferroptosis regulators in GC.Methods: We gathered five GC cohorts, namely, TCGA-STAD, GSE84437, GSE62254, GSE26901, and GSE15459. Unsupervised clustering analysis was adopted to cluster GC patients into different ferroptosis subtypes based on ferroptosis regulators. Immune cell infiltration and hallmark pathway activity were estimated via ssGSEA. The ferroptosis index was developed with the PCA computational method. Response to chemotherapy agents and small molecular compounds was inferred via GDSC, CTRP, and PRISM projects. Two anti-PD-1 therapy cohorts were gathered and the potential of FPI in predicting immune response was assessed.Results: Expression profiles, genetic mutations, DNA methylation, prognostic implications, and drug sensitivity of ferroptosis regulators were characterized in GC. Three ferroptosis subtypes were clustered with distinct prognosis, hallmark pathway activity, and tumor-infiltrating immune cells. Ferroptosis levels were quantified based on the expression of prognostic ferroptosis-related signatures. The significant relationships between FPI and clinicopathological characteristics were observed. Furthermore, high FPI was in relation to poor prognosis, inflamed tumor microenvironment (TME) as well as high sensitivity to chemotherapy agents (docetaxel and cisplatin), and CTRP- and PRISM-derived compounds. Also, FPI acted as a promising predictor of immune response.Conclusion: Collectively, our findings identified a novel ferroptosis-based subtype classification of GC, and revealed the potential of ferroptosis in forming TME diversity and complexity, and guiding individualized treatment.</p

    The complete chloroplast genome sequence of <i>Ludwigia adscendens</i> (L.) Hara, 1953 (Onagraceae)

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    Ludwigia adscendens (L.) Hara, 1953 (L. adscendens) belongs to the family Onagraceae, which is a traditional medicinal plant distributed worldwide. In this study, the first complete chloroplast genome of L. adscendens was sequenced and assembled. The assembled chloroplast genome of L. adscendens is 159,560 bp in length, containing a pair of inverted repeat region A (IRA) of 24,762 bp, inverted repeat region B (IRB) of 24,762 bp, separated by a large single-copy (LSC) sequence of 90,276 bp and a small single-copy (SSC) region of 19, 760 bp, respectively. A total of 129 genes were annotated in the entire chloroplast genome, consisting of 37 transfer RNA (tRNA) genes, 8 ribosomal RNA (rRNA) genes, and 84 protein-coding genes, with a total GC content of 37.27%. The phylogenomic analysis showed that L. adscendens was closely related to L. octovalvis in the Onagraceae family. Further evolutionary studies of the genus Ludwigia could benefit from the complete chloroplast genome of L. adscendens present in this study and the obtained results would provide useful information for future phylogenetic, taxonomic, and evolutionary studies on Onagraceae.</p

    Supplemental Material - Social media use, perceived social support, and well-being: Evidence from two waves of surveys peri- and post-COVID-19 lockdown

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    Supplemental Material for Social media use, perceived social support, and well-being: Evidence from two waves of surveys peri- and post-COVID-19 lockdown by Zhiying Yue, Renwen Zhang, and Jun Xiao in Journal of Social and Personal Relationships</p
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