Characteristics of patients with adenocarcinoma of pancreatic neck.

Characteristics of patients with adenocarcinoma of pancreatic neck.</p

Kaplan-Meier survival analysis of DP, PD and TP patients with adenocarcinoma of pancreatic neck in different AJCC stages.

A: Overall survival for stage I in DP, PD, and TP group (P = 0.962). B: Overall survival for stage II in DP, PD, and TP group (P = 0.874). C: Overall survival for stage III in DP, PD, and TP group (P = 0.942). D: Cancer-specific survival for stage I in DP, PD, and TP group (P = 0.972). E: Cancer-specific survival for stage II in DP, PD, and TP group (P = 0.790). F: Cancer-specific survival for stage III in DP, PD, and TP group (P = 0.936).</p

Univariate and multivariate analysis of cancer-specific survival in patients with surgery.

Univariate and multivariate analysis of cancer-specific survival in patients with surgery.</p

Kaplan-Meier survival analysis of all patients with adenocarcinoma of pancreatic neck.

A: Overall survival in surgery and no surgery group (P P < 0.001).</p

Comparison of characteristics in patients with different types of surgery.

Comparison of characteristics in patients with different types of surgery.</p

Univariate and multivariate analysis of overall survival in patients with surgery.

Univariate and multivariate analysis of overall survival in patients with surgery.</p

Kaplan-Meier survival analysis of DP, PD and TP patients with adenocarcinoma of pancreatic neck.

A: Overall survival in DP, PD, and TP group (P = 0.924). B: Cancer-specific survival in DP, PD, and TP group (P = 0.786).</p

Additional file 1 of Genome-wide association study identifies new loci associated with noise-induced tinnitus in Chinese populations

Additional file 1: Supplementary Figure 1. The principal components analyses (PCA) of the population in the discovery stage in this study and reference populations from the 1,000 Genomes Project. Supplementary Figure 2. The genotypes of rs2846071 are significantly associated with the expression levels of WNT11 in several types of brain tissues from GTEx. Supplementary Figure 3. Colocalization analyses of the association signals from GWAS and brain eQTL data at the 11q13.5 and 12p13.31 loci. Supplementary Figure 4. Chromatin state segmentations for rs1800692 and rs4149570 using the ENCODE data. Supplementary Figure 5. The genotypes of rs4149577 are significantly associated with the expression levels of TNFRSF1A in several types of brain tissue from GTEx. Supplementary Figure 6. Proxy plots for 11q13.5 and 12p13.31 regions in Chinese Han Chinese and European populations. Supplementary Figure 7. Linkage disequilibrium plots for 11q13.5 and 12p13.31 regions in Chinese Han Chinese and European populations. Supplementary Figure 8. Power to detect the genetic effects of rs2846071 and rs4149577. Supplementary Table 1. Summary of the case/control populations used in this study. Supplementary Table 2. Summary of the genotyped and imputed SNPs in the discovery stage. Supplementary Table 3. Summary of the SNPs that have been reported to be associated with tinnitus in previous studies. Supplementary Table 4. Summary of the top 22 SNPs in the discovery stage. Supplementary Table 5. Primers used for SNPs genotyping in the replication stage. Supplementary Table 6. Summary of the association results in the replication stage. Supplementary Table 7. Stratification analyses of rs2846071 and rs4149577 by age. Supplementary Table 8. The predicted functional relevance of rs2846071, rs4149577 and the other SNPs in strong or moderate LD with them. Supplementary Table 9. Pathway analyses based on i-GSEA4GWAS. Supplementary Table 10. The allele and genotype frequencies of rs2846071 and rs4149577 in different populations

Univariate and multivariate analysis of CSS in patients who underwent curative intent surgery for pancreatic cancer by stage.

Univariate and multivariate analysis of CSS in patients who underwent curative intent surgery for pancreatic cancer by stage.</p

Demographic and clinicopathological features of patients who underwent curative intent surgery for stage I to III pancreatic cancer by stage and location.

Demographic and clinicopathological features of patients who underwent curative intent surgery for stage I to III pancreatic cancer by stage and location.</p