26 research outputs found

    Additional file 3 of Pulmonary alveolar proteinosis in Korea: analysis of prevalence and incidence via a nationwide population-based study

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    Additional file 3: Table S3. Number of patients with pulmonary alveolar proteinosis and incidence rate (per 106 population at risk) in Korea from 2012 to 2015

    Additional file 2 of Pulmonary alveolar proteinosis in Korea: analysis of prevalence and incidence via a nationwide population-based study

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    Additional file 2: Table S2. Number of patients with pulmonary alveolar proteinosis and prevalence (per 106 population) in Korea from 2010 to 2016

    Additional file 1: of Impact of Pneumocystis jirovecii pneumonia on kidney transplant outcome

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    Table S1. Information on the patients who had graft loss after the occurrence of Pneumocystis jirovecii pneumonia. Table S2. Information on the patients who died after the diagnosis of Pneumocystis jirovecii pneumonia. (DOCX 20 kb

    MOESM1 of Reduced chronic restraint stress in mice overexpressing hyperactive proteasomes in the forebrain

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    Additional file 1: Figure S1. Enhancing proteasome activity does not affect locomotive activity, basal anxiety and fear memory. (A-B) Mice were tested in open field (33 × 33 cm) for 20 min under dim light. (A) Distance moved measured across the 20-min test session in open field test. WT, n = 5 mice; α3ΔN Tg, n = 9 mice. Unpaired t-test, p = 0.2210. (B) Time spent in center (15 cm) zone in open field test. WT, n = 5 mice; α3ΔN Tg, n = 9 mice. Unpaired t-test, p = 0.5440. (C) Time spent in closed and open arm in elevated plus maze test. WT, n = 5 mice; α3ΔN Tg, n = 9 mice. Two-way ANOVA, effect of genotype, F1, 12 = 0.1428, p = 0.7122. (D-E) Mice were trained with three tone (2.8 kHz, 85 dB, 30 s)-shock (0.5 mA, 2 s co-terminated with the tone) pairings in fear conditioning apparatus. (D) Contextual fear memory was tested in the same training apparatus for 5 min at 24 h after the training. WT, n = 11 mice; α3ΔN Tg, n = 11 mice. Unpaired t-test, p = 0.4354. (E) Auditory fear memory was tested in another chamber with the same tone for 3 min at 48 h after the training. WT, n = 11 mice; α3ΔN Tg, n = 11 mice. Unpaired t-test, p = 0.2260. Only male mice were used for open field and elevated plus maze, whereas both male and female mice were used for fear conditioning tests. Data are mean ± SEM

    Additional file 2: of Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks

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    Figure S2. Comparison of the three C57BL/6N stocks on tumor cell proliferation of mouse in LLC tumor cell transplant model using Ki-67 staining. Four different numbers (5x104, 1 x 105, 5 x 105 or 1 x 106 cells) of LLC cells were subcutaneous injected in C57BL/6NKorl, C57BL/6NA, and C57BL/6NB, respectively. The graph presents the relative expression level of Ki-67 on tumor tissue from C57BL/6NKorl, C57BL/6NA and C57BL/6NB stocks, respectively. Each group consisted of 8 mice. Data represents the mean ± S.E.M of n = 8/group (*P < 0.05 versus No group). (TIF 300dpi

    Additional file 4: of Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks

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    Figure S4. Comparison of metastasis-related proteins expression in tumor tissue collected from LLC cell bearing C57BL/6N mice stocks. Western blotting represent relative level of MMP2 and VEGF protein in the tumor tissue from each C57BL/6N stock. The graph display the relative level of protein expression in tumor tissues from cisplatin-treated LLC cells bearing C57BL/6NKorl, C57BL/6NA, and C57BL/6NB stocks, respectively. *P < 0.05 versus LLC+Ve group (TIF 300dpi
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