Update to the Brenden et al. (2012) Statistical Catch-at-age Assessment for Chinook salmon in the Main Basin of Lake Huron

<p>Bence, J. R., and Ji X. He.  2015.  Update to the Brenden et al. (2012) Statistical Catch-at-age Assessment for Chinook salmon in the Main Basin of Lake Huron.  Quantitative Fisheries Center Technical Report T2015-01.  These reports available at the Quantitative Fisheries Center web site as of May 2015.  This represents initial exploration of publishing these through figshare for permanence and wider distribution.</p

A Review of Solving Non-IID Data in Federated Learning: Current Status and Future Directions

Federated learning (FL), as a machine learning framework, has garnered substantial attention from researchers in recent years. FL makes it possible to train a global model through coordination by a central server while ensuring the privacy of data on individual edge devices. However, the data on edge devices that participate in FL training are not independently and identically distributed (IID), resulting in challenges related to heterogeneity data. In this paper, we introduce the challenges generated by non-IID data to FL and provide a detailed classification of non-IID data. Then, we summarize the existing solutions to non-IID data in FL from the perspectives of data and process. To the best of our knowledge, despite the considerable efforts achieved by many researchers in solving the non-IID problem, some issues remain unsolved. This paper provides researchers with the latest findings and analyzes the potential future directions for solving non-IID in FL

A Survey of Homogeneous and Heterogeneous Multi-source Information Fusion Based on Rough Set Theory

Multi-source information fusion (MSIF) can be defined as the process of automatically analyzing and synthesizing information and data from multiple sensors or sources based on certain standards so as to achieve the required decisions and estimates, and it includes two types of information, homogeneous information and heterogeneous information. MSIF is also referred as multi-sensor information fusion. Rough set theory (RST) provides an effective method to process uncertain, inaccurate, or incomplete data. Therefore, many homogeneous and heterogeneous MSIF approaches based on RST have been put forward. In this paper, we summarize the homogeneous and heterogeneous MSIF based RST. Firstly, we introduce the background knowledge of rough set theory and multi-source information fusion. Secondly, we classify the existing homogeneous and heterogeneous MSIF models based on RST. Then, we discuss these MSIF models and summarize their application scenarios. At the end of this paper, we propose the challenges and future trends of homogeneous and heterogeneous MSIF based on RST from the perspectives of data processing and privacy security

Table_1_Analysis of the Genomic Sequence of ABO Allele Using Next-Generation Sequencing Method.xlsx

BackgroundAlthough many molecular diagnostic methods have been used for ABO genotyping, there are few reports on the full-length genomic sequence analysis of the ABO gene. Recently, next-generation sequencing (NGS) has been shown to provide fast and high-throughput results and is widely used in the clinical laboratory. Here, we established an NGS method for analyzing the sequence of the start codon to the stop codon in the ABO gene.Study Design and MethodsTwo pairs of primers covering the partial 5’-untranslated region (UTR) to 3’-UTR of the ABO gene were designed. The sequences covering from the start codon to the stop codon of the ABO gene were amplified using these primers, and an NGS method based on the overlap amplicon was developed. A total of 110 individuals, including 88 blood donors with normal phenotypes and 22 ABO subtypes, were recruited and analyzed. All these specimens were first detected by serological tests and then determined by polymerase chain reaction sequence-based typing (PCR-SBT) and NGS. The sequences, including all the intron regions for the specimens, were analyzed by bioinformatics software.ResultsAmong the 88 blood donors with a normal phenotype, 48 homozygous individuals, 39 heterozygous individuals, and one individual with a novel O allele were found according to the results of the PCR-SBT method. Some single-nucleotide variants (SNV) in intronic regions were found to be specific for different ABO alleles from 48 homozygous individuals using the NGS method. Sequences in the coding region of all specimens using the NGS method were the same as those of the PCR-SBT method. Three intronic SNVs were found to be associated with the ABO subtypes, including one novel intronic SNV (c.28+5956T>A). Moreover, six specimens were found to exhibit DNA recombination.ConclusionAn NGS method was established to analyze the sequence from the start codon to the stop codon of the ABO gene. Two novel ABO alleles were identified, and DNA recombination was found to exist in the ABO alleles.</p

Table_3_Analysis of the Genomic Sequence of ABO Allele Using Next-Generation Sequencing Method.xlsx

BackgroundAlthough many molecular diagnostic methods have been used for ABO genotyping, there are few reports on the full-length genomic sequence analysis of the ABO gene. Recently, next-generation sequencing (NGS) has been shown to provide fast and high-throughput results and is widely used in the clinical laboratory. Here, we established an NGS method for analyzing the sequence of the start codon to the stop codon in the ABO gene.Study Design and MethodsTwo pairs of primers covering the partial 5’-untranslated region (UTR) to 3’-UTR of the ABO gene were designed. The sequences covering from the start codon to the stop codon of the ABO gene were amplified using these primers, and an NGS method based on the overlap amplicon was developed. A total of 110 individuals, including 88 blood donors with normal phenotypes and 22 ABO subtypes, were recruited and analyzed. All these specimens were first detected by serological tests and then determined by polymerase chain reaction sequence-based typing (PCR-SBT) and NGS. The sequences, including all the intron regions for the specimens, were analyzed by bioinformatics software.ResultsAmong the 88 blood donors with a normal phenotype, 48 homozygous individuals, 39 heterozygous individuals, and one individual with a novel O allele were found according to the results of the PCR-SBT method. Some single-nucleotide variants (SNV) in intronic regions were found to be specific for different ABO alleles from 48 homozygous individuals using the NGS method. Sequences in the coding region of all specimens using the NGS method were the same as those of the PCR-SBT method. Three intronic SNVs were found to be associated with the ABO subtypes, including one novel intronic SNV (c.28+5956T>A). Moreover, six specimens were found to exhibit DNA recombination.ConclusionAn NGS method was established to analyze the sequence from the start codon to the stop codon of the ABO gene. Two novel ABO alleles were identified, and DNA recombination was found to exist in the ABO alleles.</p

Table_4_Analysis of the Genomic Sequence of ABO Allele Using Next-Generation Sequencing Method.xls

BackgroundAlthough many molecular diagnostic methods have been used for ABO genotyping, there are few reports on the full-length genomic sequence analysis of the ABO gene. Recently, next-generation sequencing (NGS) has been shown to provide fast and high-throughput results and is widely used in the clinical laboratory. Here, we established an NGS method for analyzing the sequence of the start codon to the stop codon in the ABO gene.Study Design and MethodsTwo pairs of primers covering the partial 5’-untranslated region (UTR) to 3’-UTR of the ABO gene were designed. The sequences covering from the start codon to the stop codon of the ABO gene were amplified using these primers, and an NGS method based on the overlap amplicon was developed. A total of 110 individuals, including 88 blood donors with normal phenotypes and 22 ABO subtypes, were recruited and analyzed. All these specimens were first detected by serological tests and then determined by polymerase chain reaction sequence-based typing (PCR-SBT) and NGS. The sequences, including all the intron regions for the specimens, were analyzed by bioinformatics software.ResultsAmong the 88 blood donors with a normal phenotype, 48 homozygous individuals, 39 heterozygous individuals, and one individual with a novel O allele were found according to the results of the PCR-SBT method. Some single-nucleotide variants (SNV) in intronic regions were found to be specific for different ABO alleles from 48 homozygous individuals using the NGS method. Sequences in the coding region of all specimens using the NGS method were the same as those of the PCR-SBT method. Three intronic SNVs were found to be associated with the ABO subtypes, including one novel intronic SNV (c.28+5956T>A). Moreover, six specimens were found to exhibit DNA recombination.ConclusionAn NGS method was established to analyze the sequence from the start codon to the stop codon of the ABO gene. Two novel ABO alleles were identified, and DNA recombination was found to exist in the ABO alleles.</p

Table_2_Analysis of the Genomic Sequence of ABO Allele Using Next-Generation Sequencing Method.xlsx

BackgroundAlthough many molecular diagnostic methods have been used for ABO genotyping, there are few reports on the full-length genomic sequence analysis of the ABO gene. Recently, next-generation sequencing (NGS) has been shown to provide fast and high-throughput results and is widely used in the clinical laboratory. Here, we established an NGS method for analyzing the sequence of the start codon to the stop codon in the ABO gene.Study Design and MethodsTwo pairs of primers covering the partial 5’-untranslated region (UTR) to 3’-UTR of the ABO gene were designed. The sequences covering from the start codon to the stop codon of the ABO gene were amplified using these primers, and an NGS method based on the overlap amplicon was developed. A total of 110 individuals, including 88 blood donors with normal phenotypes and 22 ABO subtypes, were recruited and analyzed. All these specimens were first detected by serological tests and then determined by polymerase chain reaction sequence-based typing (PCR-SBT) and NGS. The sequences, including all the intron regions for the specimens, were analyzed by bioinformatics software.ResultsAmong the 88 blood donors with a normal phenotype, 48 homozygous individuals, 39 heterozygous individuals, and one individual with a novel O allele were found according to the results of the PCR-SBT method. Some single-nucleotide variants (SNV) in intronic regions were found to be specific for different ABO alleles from 48 homozygous individuals using the NGS method. Sequences in the coding region of all specimens using the NGS method were the same as those of the PCR-SBT method. Three intronic SNVs were found to be associated with the ABO subtypes, including one novel intronic SNV (c.28+5956T>A). Moreover, six specimens were found to exhibit DNA recombination.ConclusionAn NGS method was established to analyze the sequence from the start codon to the stop codon of the ABO gene. Two novel ABO alleles were identified, and DNA recombination was found to exist in the ABO alleles.</p

Behaviour Domains: frequency of behavioral impairments.

15 patients had disinhibition, 13 patients had apathy/inertia, 3 patients had loss of sympathy/empathy, 3 patients had perseverative/stereotype, and 1 patient had change in eating behavior.</p

Amendments in the Chinese version compared to the original English version.

<p>Amendments in the Chinese version compared to the original English version.</p

Performances in cognitive scores and ECAS time of ALS patients and healthy controls.

<p>Performances in cognitive scores and ECAS time of ALS patients and healthy controls.</p