Graphical illustration of Pearson’s product moment correlation of SUV_max vs. ADC _aver.

<p>The scatter plot demonstrates a weak negative correlation between SUV_max and ADC_aver (R = −0.24), which is statistically not significant (p = 0.179).</p

Sequence parameters.

<p>Abbreviations: VIBE: Volume Interpolated Breathhold Examination, TIRM: Turbo Inversion Recovery, SE: spin echo, FSE: fast spin echo, FoV: field of view, DWI: diffusion weighted imaging, fs: fat saturated.</p

Mean and standard deviation (mean±SD) in milliliters (<i>ml</i>) of the interobserver variability of two MDs in 2D and 3D for both groups.

Significant different p-values are marked in bold.</p

2D US scans of the neck region for an exemplary volunteer.

a) Width and depth of right thyroid lobe marked, b) Length of right thyroid lobe marked.</p

Bland-Altman plots for the interobserver variability between sets of two medical doctors from Group 2.

All values are given in ml. Row 1, 2 and 3 show results between MD 1 and MD 2, MD 1 and MD 3, and MD 2 and MD 3, respectively. The columns show the results for 2D (left) and 3D measurements (right).</p

Patient with a biopsy proven prostate cancer of the right transitional zone (Gleason score 3+4 = 7).

<p>Images from simultaneous [¹⁸F] choline PET/MRI. A) T2-weighted image showing an ill-defined hypo-intense lesion of the right transitional zone. B) Diffusion-weighted image at a b-value of 1000 displaying a hyper-intense signal within the lesion indicating restricted water diffusion. C) ADC map with a corresponding hypo-intensity of the lesion. D) PET image showing a focal uptake of (18F) choline of the lesion. E) Fused MRI/PET image.</p

Fig 1 -

T1 VIBE MRI of the neck region for an exemplary volunteer, a) axial view, b) sagittal view, c) coronal view.</p

Mean and standard deviation (mean±SD) in percent (%) of the intraobserver variability for each MD in 2D and 3D for both groups (Gr. 1 and 2).

The last column shows whether a significant difference exists between the averaged 2D and 3D volume estimation sets, being the significant different p-values in bold.</p

Patient with a biopsy proven prostate cancer (Gleason score 3+4 = 7) of the left peripheral and transitional zone. Images from simultaneous [¹⁸F] choline PET/MRI.

<p>A) T2-weighted image displaying a large hypo-intense lesion of the left peripheral and transitional zone. B) Diffusion-weighted image (b = 1000) showing a hyper-intense signal of the lesion. C) Corresponding ADC map with a hypo-intense delineation of the lesion. D) PET image indicating of focal choline uptake of the lesion. E) Fused MRI/PET image.</p

Pearson’s product moment correlation of SUV_mean vs. ADC _aver.

<p>The scatter plot indicates a weak negative correlation between SUV_max and ADC_aver (R = −0.27), which is statistically not significant (p = 0.136).</p