57 research outputs found

    Actuarial Model Assumptions for Australian Inflation, Equity Returns, and Interest Rates

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    Though actuaries have developed several types of stochastic investment models for inflation, stock market returns, and interest rates, there are two commonly used in practice: autoregressive time series models with normally distributed errors, and autoregressive conditional heteroscedasticity (ARCH) models. ARCH models are particularly suited when there is heteroscedasticity in inflation and interest rate series. In such cases nonnormal residuals are found in the empirical data. This paper examines whether Australian univariate inflation and interest rate data are consistent with autoregressive time series and ARCH model assumptions

    Additional file 2 of Long noncoding RNA SNHG17 induced by YY1 facilitates the glioma progression through targeting miR-506-3p/CTNNB1 axis to activate Wnt/β-catenin signaling pathway

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    Additional file 2: Figure S2. (A) RT-qPCR results of YY1 and SNHG17 and western blot result of YY1 in U87 cells transfected with sh-NC, sh-YY1, or sh-YY1 + pcDNA3.1/SNHG17. **P < 0.01

    Additional file 1 of Long noncoding RNA SNHG17 induced by YY1 facilitates the glioma progression through targeting miR-506-3p/CTNNB1 axis to activate Wnt/β-catenin signaling pathway

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    Additional file 1: Figure S1. (A) Pearson’s correlation analysis demonstrated that YY1 was positively corrected with SNHG17. (B-C) The effects of SNHG17 overexpression on proliferation and apoptosis were shown. (D) 20 miRNAs could bind to both CTNNB1 and SNHG17. (E) RT-qPCR evaluated 20 miRNAs expressions in cells transfected with sh-SNHG17#1. (F-G) RNA pull down was used to validate the interactions of miR-506-3p with SNHG17 and CTNNB1. (H) RT-qPCR and western blot were conducted to measure CTNNB1 expression and the level of its protein β-catenin in cells transfected with NC mimics, miR-506-3p mimics, miR-506-3p mimics + pcDNA3.1, miR-506-3p mimics + pcDNA3.1/SNHG17 (Mut) or miR-506-3p mimics + pcDNA3.1/SNHG17. **P < 0.01

    Each dimension and the overall market operation state "hot and cold" interval table.

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    Each dimension and the overall market operation state "hot and cold" interval table.</p

    Table1_Heat stress inhibits the proliferation and differentiation of myoblasts and is associated with damage to mitochondria.docx

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    Introduction: Heat stress is harmful to the health of humans and animals, more and more common, as a consequence of global warming, while the mechanism that heat stress modulates skeletal development remains unknown. Hence, we conducted a model of heat stress in vitro.Methods: We used Hu sheep myoblasts as the research object, real-time quantitative PCR (RT-qPCR) and western blot (WB) were conducted to detect the expression of mRNA and protein in heat-stressed myoblasts. The would-healing assay was used to detect the migration of myoblasts. The mitochondria were observed by a transmission electron microscope.Results: mRNA and protein expression of HSP60 was significantly enriched in the heat-stressed myoblasts during proliferation and differentiation (p Discussion: This work demonstrates that heat stress inhibits proliferation and differentiation, and accelerates apoptosis by impairing mitochondrial function and promoting autophagy, which provides a mechanism to understand heat stress affects the development of the skeletal muscle.</p

    Evaluation index system of primary market operation status of residential land.

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    Evaluation index system of primary market operation status of residential land.</p

    Spider web diagram of the residential land market status (F) composite index of city.

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    Spider web diagram of the residential land market status (F) composite index of city.</p
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