Kepler Observations of V447 Lyr: An Eclipsing U Gem Cataclysmic Variable

We present the results of an analysis of data covering 1.5 years of the dwarf nova V447 Lyr. We detect eclipses of the accretion disk by the mass donating secondary star every 3.74 hrs which is the binary orbital period. V447 Lyr is therefore the first dwarf nova in the Kepler field to show eclipses. We also detect five long outbursts and six short outbursts showing V447 Lyr is a U Gem type dwarf nova. We show that the orbital phase of the mid-eclipse occurs earlier during outbursts compared to quiescence and that the width of the eclipse is greater during outburst. This suggests that the bright spot is more prominent during quiescence and that the disk is larger during outburst than quiescence. This is consistent with an expansion of the outer disk radius due to the presence of high viscosity material associated with the outburst, followed by a contraction in quiescence due to the accretion of low angular momentum material. We note that the long outbursts appear to be triggered by a short outburst, which is also observed in the super-outbursts of SU UMa dwarf novae as observed using Kepler.Comment: Accepted by MNRA

Long-term monitoring in IC4665: Fast rotation and weak variability in very low mass objects

We present the combined results of three photometric monitoring campaigns targeting very low mass (VLM) stars and brown dwarfs in the young open cluster IC4665 (age ~40 Myr). In all three runs, we observe ~100 cluster members, allowing us for the first time to put limits on the evolution of spots and magnetic activity in fully convective objects on timescales of a few years. For 20 objects covering masses from 0.05 to 0.5 Msol we detect a periodic flux modulation, indicating the presence of magnetic spots co-rotating with the objects. The detection rate of photometric periods (~20%) is significantly lower than in solar-mass stars at the same age, which points to a mass dependence in the spot properties. With two exceptions, none of the objects exhibit variability and thus spot activity in more than one season. This is contrary to what is seen in solar-mass stars and indicates that spot configurations capable of producing photometric modulations occur relatively rarely and are transient in VLM objects. The rotation periods derived in this paper range from 3 to 30h, arguing for a lack of slow rotators among VLM objects. The periods fit into a rotational evolution scenario with pre-main sequence contraction and moderate (40-50%) angular momentum losses due to wind braking. By combining our findings with literature results, we identify two regimes of rotational and magnetic properties, called C- and I-sequence. Main properties on the C-sequence are fast rotation, weak wind braking, Halpha emission, and saturated activity levels, while the I-sequence is characterised by slow rotation, strong wind braking, no Halpha emission, and linear activity-rotation relationship. Rotation rate and stellar mass are the primary parameters that determine in which regime an object is found. (abridged)Comment: 16 pages, 10 figures, accepted for publication in MNRA

Rotation of young stars in Cepheus OB3b

We present a photometric study of I-band variability in the young association Cepheus OB3b. The study is sensitive to periodic variability on time-scales of less than a day, to more than 20 d. After rejection of contaminating objects using V, I, R and narrow-band Hα photometry, we find 475 objects with measured rotation periods, which are very likely pre-main-sequence members of the Cep OB3b star-forming region. We revise the distance and age to Cep OB3b, putting it on the self-consistent age and distance ladder of Mayne & Naylor. This yields a distance modulus of 8.8 ± 0.2 mag, corresponding to a distance of 580 ± 60 pc, and an age of 4–5 Myr. The rotation period distribution confirms the general picture of rotational evolution in young stars, exhibiting both the correlation between accretion (determined in this case through narrow-band Hα photometry) and rotation expected from disc locking, and the dependence of rotation upon mass that is seen in other star-forming regions. However, this mass dependence is much weaker in our data than found in other studies. Comparison to the similarly aged NGC 2362 shows that the low-mass stars in Cep OB3b are rotating much more slowly. This points to a possible link between star-forming environment and rotation properties. Such a link would call into question models of stellar angular momentum evolution, which assume that the rotational period distributions of young clusters and associations can be assembled into an evolutionary sequence, thus ignoring environmental effects

Rotation, activity, and lithium abundance in cool binary stars

We have used two robotic telescopes to obtain time-series high-resolution spectroscopy and V I and/or by photometry for a sample of 60 active stars. Orbital solutions are presented for 26 SB2 and 19 SB1 systems with unprecedented phase coverage and accuracy. The total of 6,609 R=55,000 echelle spectra are also used to systematically determine effective temperatures, gravities, metallicities, rotational velocities, lithium abundances and absolute H{\alpha}-core fluxes as a function of time. The photometry is used to infer unspotted brightness, V - I and/or b - y colors, spot-induced brightness amplitudes and precise rotation periods. Our data are complemented by literature data and are used to determine rotation-temperature-activity relations for active binary components. We also relate lithium abundance to rotation and surface temperature. We find that 74% of all known rapidly-rotating active binary stars are synchronized and in circular orbits but 26% are rotating asynchronously of which half have Prot > Porb and e > 0. Because rotational synchronization is predicted to occur before orbital circularization active binaries should undergo an extra spin-down besides tidal dissipation. We suspect this to be due to a magnetically channeled wind with its subsequent braking torque. We find a steep increase of rotation period with decreasing effective temperature for active stars. For inactive, single giants with Prot > 100 d, the relation is much weaker. Our data also indicate a period-activity relation for H{\alpha} of the form RH{\alpha} \propto P - 0.24 for binaries and RH{\alpha} \propto P -0.14 for singles. Lithium abundances in our sample increase with effective temperature. On average, binaries of comparable effective temperature appear to exhibit 0.25 dex less surface lithium than singles. We also find a trend of increased Li abundance with rotational period of form log n(Li) \propto - 0.6 log Prot

Efficacy of primary series AZD1222 (ChAdOx1 nCoV-19) vaccination against SARS-CoV-2 variants of concern: Final analysis of a randomized, placebo-controlled, phase 1b/2 study in South African adults (COV005)

COVID-19 vaccine efficacy (VE) has been observed to vary against antigenically distinct SARS-CoV-2 variants of concern (VoC). Here we report the final analysis of VE and safety from COV005: a phase 1b/2, multicenter, double-blind, randomized, placebo-controlled study of primary series AZD1222 (ChAdOx1 nCoV-19) vaccination in South African adults aged 18-65 years. South Africa's first, second, and third waves of SARS-CoV-2 infections were respectively driven by the ancestral SARS-CoV-2 virus (wild type, WT), and SARS-CoV-2 Beta and Delta VoCs. VE against asymptomatic and symptomatic infection was 90.6% for WT, 6.7% for Beta and 77.1% for Delta. No cases of severe COVID-19 were documented ahead of unblinding. Safety was consistent with the interim analysis, with no new safety concerns identified. Notably, South Africa's Delta wave occurred ≥ 9 months after primary series vaccination, suggesting that primary series AZD1222 vaccination offers a good durability of protection, potentially due to an anamnestic response. Clinical trial identifier: CT.gov NCT04444674

Shakespeare in the Park: The Tempest - Hervey Bay

Series of performances with USQ Acting students & USQ Alumni, in connection with the Shakespeare in the Park Festival: in Queens Park (Toowoomba) from the 26th of February to the 7th of March 2009; USQ Campus (Springfield) from the 12th to the 14th of March 2009, and; Seafront Oval (Hervey Bay) from the 19th to the 21st of March 2009

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records

BACKGROUND: Updatable estimates of COVID-19 onset, progression, and trajectories underpin pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to define and validate ten COVID-19 phenotypes from nationwide linked electronic health records (EHR) using an extensible framework. METHODS: In this cohort study, we used eight linked National Health Service (NHS) datasets for people in England alive on Jan 23, 2020. Data on COVID-19 testing, vaccination, primary and secondary care records, and death registrations were collected until Nov 30, 2021. We defined ten COVID-19 phenotypes reflecting clinically relevant stages of disease severity and encompassing five categories: positive SARS-CoV-2 test, primary care diagnosis, hospital admission, ventilation modality (four phenotypes), and death (three phenotypes). We constructed patient trajectories illustrating transition frequency and duration between phenotypes. Analyses were stratified by pandemic waves and vaccination status. FINDINGS: Among 57 032 174 individuals included in the cohort, 13 990 423 COVID-19 events were identified in 7 244 925 individuals, equating to an infection rate of 12·7% during the study period. Of 7 244 925 individuals, 460 737 (6·4%) were admitted to hospital and 158 020 (2·2%) died. Of 460 737 individuals who were admitted to hospital, 48 847 (10·6%) were admitted to the intensive care unit (ICU), 69 090 (15·0%) received non-invasive ventilation, and 25 928 (5·6%) received invasive ventilation. Among 384 135 patients who were admitted to hospital but did not require ventilation, mortality was higher in wave 1 (23 485 [30·4%] of 77 202 patients) than wave 2 (44 220 [23·1%] of 191 528 patients), but remained unchanged for patients admitted to the ICU. Mortality was highest among patients who received ventilatory support outside of the ICU in wave 1 (2569 [50·7%] of 5063 patients). 15 486 (9·8%) of 158 020 COVID-19-related deaths occurred within 28 days of the first COVID-19 event without a COVID-19 diagnoses on the death certificate. 10 884 (6·9%) of 158 020 deaths were identified exclusively from mortality data with no previous COVID-19 phenotype recorded. We observed longer patient trajectories in wave 2 than wave 1. INTERPRETATION: Our analyses illustrate the wide spectrum of disease trajectories as shown by differences in incidence, survival, and clinical pathways. We have provided a modular analytical framework that can be used to monitor the impact of the pandemic and generate evidence of clinical and policy relevance using multiple EHR sources. FUNDING: British Heart Foundation Data Science Centre, led by Health Data Research UK