Mass-Transfer-Induced Multistep Phase Separation in Emulsion Droplets: Toward Self-Assembly Multilayered Emulsions and Onionlike Microspheres

Mass-transfer-induced multistep phase separation was found in emulsion droplets. The agent system consists of a monomer (ethoxylated trimethylolpropane triacrylate, ETPTA), an oligomer (polyethylene glycol diacrylate, PEGDA 700), and water. The PEGDA in the separated layers offered partial miscibility of all the components throughout the multistep phase-separation procedure, which was terminated by the depletion of PEGDA in the outermost layer. The number of separated portions was determined by the initial PEGDA content, and the initial droplet size influenced the mass-transfer process and consequently determined the sizes of the separated layers. The resultant multilayered emulsions were demonstrated to offer an orderly temperature-responsive release of the inner cores. Moreover, the emulsion droplets can be readily solidified into onionlike microspheres by ultraviolet light curing, providing a new strategy in designing particle structures

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Microfluidic Assembly of Microblocks into Interlocked Structures for Enhanced Strength and Toughness

Compared with monolithic materials, topologically interlocked materials (TIMs) exhibit higher toughness based on their enhanced crack deflection and deformation tolerance. Importantly, by reducing the block size of TIMs, their structural strength can also be improved due to the reduced flexural span. However, the assembly of microscale blocks remains a huge challenge due to the inadequacy of nanoscale self-assembly or macroscale pick-and-place operations. In this work, octahedral microblocks are fabricated and constructed into interlocked structures with different patterns through microfluidic channels with variable cross sections. The pattern of the interlocked panel is demonstrated to affect its strength and toughness. The failure strength and energy absorption of assembled panels significantly exceed that of their monolithic counterpart by ∼33% and ∼19.1 folds, respectively. Generally, the presented microfluidic method provides a unique technique for the assembly of interlocked architecture, which facilitates the design and fabrication of TIMs with highly improved strength and toughness

Enhanced Anticoagulation of Hierarchy Liquid Infused Surfaces in Blood Flow

Liquid infused surfaces (LIS) hold remarkable potential in anticoagulation. However, liquid loss of LIS in the bloodstream remains a challenge toward its clinical application. Here, micronano hierarchy structures are obtained on the titanium alloy substrate by regulating the microspheres’ distribution. When the gap between the microspheres is smaller than the diameter of the red blood cell (RBC), the LIS is more stable under the blood wash and presents a better anticoagulation performance. The proper interval is found to prevent the RBCs from entering the gap and remove the liquid on the surface. The retained thickness of the liquid film is measured by the atomic force microscopy (AFM) technique. The LIS is applied on the front guide vane of an artificial heart pump and exhibits significant improvement on anticoagulation in the blood circulation in vitro for 25 h. The techniques and findings can be used to optimize the anticoagulation performance of LIS-related biomedical implant devices

Fabrication of Ceramic Microspheres by Diffusion-Induced Sol–Gel Reaction in Double Emulsions

We demonstrate an approach to prepare zirconium dioxide (ZrO2) microspheres by carrying out a diffusion-induced sol–gel reaction inside double emulsion droplets. A glass capillary microfluidic device is introduced to generate monodisperse water-in-oil-in-water (W/O/W) double emulsions with a zirconium precursor as the inner phase. By adding ammonia to the continuous aqueous phase, the zirconium precursor solution is triggered to gel inside the emulsions. The double emulsion structure enhances the uniformity in the rate of the sol–gel reaction, resulting in sol–gel microspheres with improved size uniformity and sphericity. ZrO2 ceramic microspheres are formed following subsequent drying and sintering steps. Our approach, which combines double-emulsion-templating and sol–gel synthesis, has great potential for fabricating versatile ceramic microspheres for applications under high temperature and pressure