Inland China : A Sustainable Tourism Development Framework

Description to be added</p

Dataset-J of Ecology-Zilong

These data were collected in a boreal forest of Canad

A Novel Stereocontrolled Synthesis of 1,2-<i>trans</i> Cyclopropyl Ketones via Suzuki-Type Coupling of Acid Chlorides with Cyclopropylboronic Acids

The palladium-catalyzed cross-coupling reaction of cyclopropylboronic acids with acyl chlorides was achieved by the combination of Ag2O and K2CO3 as the base. Highly enantiomerically enriched cyclopropyl ketones (ee >90%) were also obtained by the reaction of corresponding chiral cyclopropylboronic acids

FiMAP analysis results for body weight in the UK Biobank.

Start and end positions in centimorgan (cM) are shown, along with the number of non-zero off-diagonal elements in each N × N local IBD matrix and finite-sample p values (N = 407,400). (XLSX)</p

FiMAP analysis results for body mass index in the UK Biobank.

Start and end positions in centimorgan (cM) are shown, along with the number of non-zero off-diagonal elements in each N × N local IBD matrix and finite-sample p values (N = 407,255). (XLSX)</p

FiMAP analysis results for standing height in the UK Biobank.

Start and end positions in centimorgan (cM) are shown, along with the number of non-zero off-diagonal elements in each N × N local IBD matrix and finite-sample p values (N = 407,681). (XLSX)</p

Power comparison of FiMAP and GWAS.

(A) Untyped rare causal variants, 1 cM causal window; (B) Untyped rare causal variants, 1 cM neighboring windows; (C) Haplotype effects, 1 cM causal window; (D) Haplotype effects, 1 cM neighboring windows. In each simulation replicate, finite-sample FiMAP with local IBD matrices constructed from RaPID and hap-IBD IBD segments called with length ≥ 3 cM, 5 cM, 10 cM were benchmarked with a GWAS single-variant test. Empirical power was estimated for FiMAP as the proportion of finite-sample p values less than 0.05/3,403 = 1.47 × 10−5, and for GWAS as the proportion of any minimum single-variant p values in each 1 cM testing window less than 5 × 10−8, over 1,000 simulation replicates.</p

Local and global IBD matrices in FiMAP.

The global IBD matrix Φ is the average of the local IBD matrices Ψl along the genome dimension of the genotype similarity tensor.</p

Comparison of finite-sample FiMAP p values from RaPID IBD segments before and after conditioning on GWAS tag variants in the testing window and flanking regions.

(A) Waist circumference; (B) Hip circumference; (C) Standing height; (D) Sitting height; (E) Body mass index; (F) Body weight. IBD segments called by RaPID with length ≥ 3 cM were used in the FiMAP analysis. Dashed lines represented the Bonferroni-corrected significance level of 0.05/3,403 = 1.47 × 10−5. Only significant unconditional FiMAP p values were shown. P values −50 for standing and sitting height were truncated at 1 × 10−50. FiMAP conditional p-values that no longer reach significance were shown in blue.</p

FiMAP analysis results for hip circumference in the UK Biobank.

Start and end positions in centimorgan (cM) are shown, along with the number of non-zero off-diagonal elements in each N × N local IBD matrix and finite-sample p values (N = 407,827). (XLSX)</p