The role of the family in resettlement

This practitioner’s guide unpicks different interpretations of ‘family’. It explores the family’s unique position to fulfil key characteristics that research has shown are associated with effective resettlement support. It highlights recommendations and considerations that can be adopted into the practices of those working with young people and their families. As well as outlining various ways that families can help with personal and structural support, the guide also provides tips for successfully engaging with family members and sets out ways of overcoming the challenges that exist to unlocking this important resource

Functional complementation between FADD and RIP1 in embryos and lymphocytes.

FADD is a common adaptor shared by several death receptors for signalling apoptosis through recruitment and activation of caspase 8 (refs 1-3). Death receptors are essential for immune homeostasis, but dispensable during embryogenesis. Surprisingly, Fadd(-/-) mice die in utero and conditional deletion of FADD leads to impaired lymphocyte proliferation. How FADD regulates embryogenesis and lymphocyte responses has been a long-standing enigma. FADD could directly bind to RIP1 (also known as RIPK1), a serine/threonine kinase that mediates both necrosis and NF-κB activation. Here we show that Fadd(-/-) embryos contain raised levels of RIP1 and exhibit massive necrosis. To investigate a potential in vivo functional interaction between RIP1 and FADD, null alleles of RIP1 were crossed into Fadd(-/-) mice. Notably, RIP1 deficiency allowed normal embryogenesis of Fadd(-/-) mice. Conversely, the developmental defect of Rip1(-/-) lymphocytes was partially corrected by FADD deletion. Furthermore, RIP1 deficiency fully restored normal proliferation in Fadd(-/-) T cells but not in Fadd(-/-) B cells. Fadd(-/-)Rip1(-/-) double-knockout T cells are resistant to death induced by Fas or TNF-α and show reduced NF-κB activity. Therefore, our data demonstrate an unexpected cell-type-specific interplay between FADD and RIP1, which is critical for the regulation of apoptosis and necrosis during embryogenesis and lymphocyte function

Challenges of regulatory theory and practice : a study of hawker control in Hong Kong

published_or_final_versionPolitics and Public AdministrationMasterMaster of Public Administratio

Can sacrificial feeding areas protect aquatic plants from herbivore grazing? Using behavioural ecology to inform wildlife management

Effective wildlife management is needed for conservation, economic and human well-being objectives. However, traditional population control methods are frequently ineffective, unpopular with stakeholders, may affect non-target species, and can be both expensive and impractical to implement. New methods which address these issues and offer effective wildlife management are required. We used an individual-based model to predict the efficacy of a sacrificial feeding area in preventing grazing damage by mute swans (Cygnus olor) to adjacent river vegetation of high conservation and economic value. The accuracy of model predictions was assessed by a comparison with observed field data, whilst prediction robustness was evaluated using a sensitivity analysis. We used repeated simulations to evaluate how the efficacy of the sacrificial feeding area was regulated by (i) food quantity, (ii) food quality, and (iii) the functional response of the forager. Our model gave accurate predictions of aquatic plant biomass, carrying capacity, swan mortality, swan foraging effort, and river use. Our model predicted that increased sacrificial feeding area food quantity and quality would prevent the depletion of aquatic plant biomass by swans. When the functional response for vegetation in the sacrificial feeding area was increased, the food quantity and quality in the sacrificial feeding area required to protect adjacent aquatic plants were reduced. Our study demonstrates how the insights of behavioural ecology can be used to inform wildlife management. The principles that underpin our model predictions are likely to be valid across a range of different resource-consumer interactions, emphasising the generality of our approach to the evaluation of strategies for resolving wildlife management problems

Elevated temperature material properties of stainless steel reinforcing bar

Corrosion of carbon steel reinforcing bar can lead to deterioration of concrete structures, especially in regions where road salt is heavily used or in areas close to sea water. Although stainless steel reinforcing bar costs more than carbon steel, its selective use for high risk elements is cost-effective when the whole life costs of the structure are taken into account. Considerations for specifying stainless steel reinforcing bars and a review of applications are presented herein. Attention is then given to the elevated temperature properties of stainless steel reinforcing bars, which are needed for structural fire design, but have been unexplored to date. A programme of isothermal and anisothermal tensile tests on four types of stainless steel reinforcing bar is described: 1.4307 (304L), 1.4311 (304LN), 1.4162 (LDX 2101®) and 1.4362 (2304). Bars of diameter 12 mm and 16 mm were studied, plain round and ribbed. Reduction factors were calculated for the key strength, stiffness and ductility properties and compared to equivalent factors for stainless steel plate and strip, as well as those for carbon steel reinforcement. The test results demonstrate that the reduction factors for 0.2% proof strength, strength at 2% strain and ultimate strength derived for stainless steel plate and strip can also be applied to stainless steel reinforcing bar. Revised reduction factors for ultimate strain and fracture strain at elevated temperatures have been proposed. The ability of two-stage Ramberg-Osgood expressions to capture accurately the stress-strain response of stainless steel reinforcement at both room temperature and elevated temperatures is also demonstrated