Phylogenetic analysis based on the 915-nucleotide VP1 gene of CA24v.

<p>All Jiangsu CA24v isolates identified in this study, marked with black triangles, were compared with strains available in GenBank. Strains for which the complete sequences of both the 3Cpro and VP1 regions were available are indicated **. The MEGA 4.0 software was used for the phylogenetic analysis. The stability of the nodes was assessed using neighbor-joining cluster analysis with 1000 bootstrap replications, and only bootstrap values >70% are shown at the nodes.</p

Amino acid mutations in the 3Cpro region in different genotypes of CA24v.

*<p>Amino acid mutation only present in all GIV-C5 strains.</p

AHC cases reported to NDSIMS in Jiangsu from 2007 to 2010.

<p>AHC cases reported to NDSIMS in Jiangsu from 2007 to 2010.</p

Homology of the complete VP1 regions of the strains in different clusters within CA24v genotype GIV in this study.

<p>Homology of the complete VP1 regions of the strains in different clusters within CA24v genotype GIV in this study.</p

Distribution of the reported AHC cases in Jiangsu Province during the outbreak of September 2010.

<p>Distribution of the reported AHC cases in Jiangsu Province during the outbreak of September 2010.</p

Amino acid mutations in the VP1 region in different genotypes of CA24v.

*<p>Amino acid mutation only present in all GIV-C5 strains.</p

Phylogenetic analysis based on the 549-nucleotide 3Cpro gene of CA24v.

<p>All Jiangsu CA24v isolates identified in this study, marked with black triangles, were compared with strains available in GenBank. Strains for which the complete sequences of both the 3Cpro and VP1 regions were available are indicated with **. The MEGA 4.0 software was used for the phylogenetic analysis. The stability of the nodes was assessed using neighbor-joining cluster analysis with 1000 bootstrap replications, and only bootstrap values >70% are shown at the nodes.</p

Homology of the complete 3Cpro regions of the strains in different clusters within CA24v genotype GIV investigated in this study.

<p>Homology of the complete 3Cpro regions of the strains in different clusters within CA24v genotype GIV investigated in this study.</p

Local autocorrelation analysis for Shigella in Jiangsu Province.

<p>Local autocorrelation analysis for Shigella in Jiangsu Province.</p

Spatial distribution of proportion of EV71, CA16 and the other EVs HFMD during 2009–2013 in Jiangsu province, Eastern China.

<p>A. Spatial distribution of proportion of CA16 of HFMD cases. B. Spatial distribution of proportion of EV71 of HFMD cases. C. Spatial distribution of proportion of the other EVs of HFMD cases.</p