Multifunctionality and Crystal Dynamics of a Highly Stable, Porous Metal−Organic Framework [Zn₄O(NTB)₂]

A porous metal−organic framework [Zn4O(NTB)2]·3DEF·EtOH (1), in which (3,6)-connected nets are doubly interpenetrated to generate curved three-dimensional channels, has been prepared. Framework 1 exhibits high permanent porosity (Langmuir surface area, 1121 m2/g; pore volume, 0.51 cm3/cm3), high thermal stability (up to 430 °C), high hydrogen adsorption capacity (1.9 wt % at 77 K and 1 atm), selective organic guest binding ability (Kf :  MeOH > pyridine > benzene > dodecane), and guest-dependent blue luminescence (λmax depending on guest identity). Most interestingly, the framework sustains single crystallinity even at 400 °C and 10-5 Torr, and the framework components undergo reversible dynamics, mainly rotational motion, in response to removal and rebinding of the guest molecules

Multifunctionality and Crystal Dynamics of a Highly Stable, Porous Metal−Organic Framework [Zn₄O(NTB)₂]

A porous metal−organic framework [Zn4O(NTB)2]·3DEF·EtOH (1), in which (3,6)-connected nets are doubly interpenetrated to generate curved three-dimensional channels, has been prepared. Framework 1 exhibits high permanent porosity (Langmuir surface area, 1121 m2/g; pore volume, 0.51 cm3/cm3), high thermal stability (up to 430 °C), high hydrogen adsorption capacity (1.9 wt % at 77 K and 1 atm), selective organic guest binding ability (Kf :  MeOH > pyridine > benzene > dodecane), and guest-dependent blue luminescence (λmax depending on guest identity). Most interestingly, the framework sustains single crystallinity even at 400 °C and 10-5 Torr, and the framework components undergo reversible dynamics, mainly rotational motion, in response to removal and rebinding of the guest molecules

Multifunctionality and Crystal Dynamics of a Highly Stable, Porous Metal−Organic Framework [Zn₄O(NTB)₂]

A porous metal−organic framework [Zn4O(NTB)2]·3DEF·EtOH (1), in which (3,6)-connected nets are doubly interpenetrated to generate curved three-dimensional channels, has been prepared. Framework 1 exhibits high permanent porosity (Langmuir surface area, 1121 m2/g; pore volume, 0.51 cm3/cm3), high thermal stability (up to 430 °C), high hydrogen adsorption capacity (1.9 wt % at 77 K and 1 atm), selective organic guest binding ability (Kf :  MeOH > pyridine > benzene > dodecane), and guest-dependent blue luminescence (λmax depending on guest identity). Most interestingly, the framework sustains single crystallinity even at 400 °C and 10-5 Torr, and the framework components undergo reversible dynamics, mainly rotational motion, in response to removal and rebinding of the guest molecules

Multifunctionality and Crystal Dynamics of a Highly Stable, Porous Metal−Organic Framework [Zn₄O(NTB)₂]

A porous metal−organic framework [Zn4O(NTB)2]·3DEF·EtOH (1), in which (3,6)-connected nets are doubly interpenetrated to generate curved three-dimensional channels, has been prepared. Framework 1 exhibits high permanent porosity (Langmuir surface area, 1121 m2/g; pore volume, 0.51 cm3/cm3), high thermal stability (up to 430 °C), high hydrogen adsorption capacity (1.9 wt % at 77 K and 1 atm), selective organic guest binding ability (Kf :  MeOH > pyridine > benzene > dodecane), and guest-dependent blue luminescence (λmax depending on guest identity). Most interestingly, the framework sustains single crystallinity even at 400 °C and 10-5 Torr, and the framework components undergo reversible dynamics, mainly rotational motion, in response to removal and rebinding of the guest molecules

Multifunctionality and Crystal Dynamics of a Highly Stable, Porous Metal−Organic Framework [Zn₄O(NTB)₂]

A porous metal−organic framework [Zn4O(NTB)2]·3DEF·EtOH (1), in which (3,6)-connected nets are doubly interpenetrated to generate curved three-dimensional channels, has been prepared. Framework 1 exhibits high permanent porosity (Langmuir surface area, 1121 m2/g; pore volume, 0.51 cm3/cm3), high thermal stability (up to 430 °C), high hydrogen adsorption capacity (1.9 wt % at 77 K and 1 atm), selective organic guest binding ability (Kf :  MeOH > pyridine > benzene > dodecane), and guest-dependent blue luminescence (λmax depending on guest identity). Most interestingly, the framework sustains single crystallinity even at 400 °C and 10-5 Torr, and the framework components undergo reversible dynamics, mainly rotational motion, in response to removal and rebinding of the guest molecules

Flowchart of the selection of study participants.

*Methotrexate, sulfasalazine, hydroxychloroquine, leflunomide, tacrolimus, bucillamine, mizoribine, cyclosporine, infliximab, etanercept, adalimumab, golimumab, abatacept, tocilizumab, rituximab, and tofacitinib. **Systemic connective tissue disorders (International Classification of Diseases 10th revision [ICD-10] code: M30-M36), ankylosing spondylitis (ICD-10 code: M45), psoriatic and enteropathic arthropathies (ICD-10 code: M07), or juvenile arthritis (ICD-10 code: M08). RA, rheumatoid arthritis; DMARD, disease-modifying anti-rheumatic drug.</p

Health expenditure per capita for the rheumatoid arthritis (RA) and control group.

For interpretation, 1 US dollar is equal to 1100 Korean dollars. (A) Total health care costs. (B) Amount of out-of-pocket payment.</p

Comparison of mortality between the RA and control groups.

Comparison of mortality between the RA and control groups.</p

Comparison of rate, type, and distribution of disability between the RA and control groups.

Comparison of rate, type, and distribution of disability between the RA and control groups.</p

A Redox-Active Two-Dimensional Coordination Polymer: Preparation of Silver and Gold Nanoparticles and Crystal Dynamics on Guest Removal

A two-dimensional (2D) square-grid coordination polymer, {[Ni(cyclam)]2[BPTC]}n·2nH2O (1), has been assembled from [Ni(cyclam)](ClO4)2 (cyclam = 1,4,8,11-tetraazacyclotetradecane) and H4BPTC (H4BPTC = 1,1‘-biphenyl-2,2‘,6,6‘-tetracarboxylic acid) in H2O/MeOH (2.5:1, v/v) in the presence of triethylamine. When solid 1 was immersed in the EtOH solutions of AgNO3 (1.3 × 10-1 M) and NaAuCl4·2H2O (3.4 × 10-2 M), respectively, for 5 min at room temperature, solids including Ag (3.7 ± 0.4 nm, diameter) and Au (2 nm, diameter) nanoparticles were formed by the redox reactions between Ni(II) ions incorporated in 1 and metal ions, as evidenced by HRTEM images, EPR, and XPS spectra. When single-crystal 1 was heated at 180 °C under 10-5 Torr for 24 h, it was transformed to dehydrated compound {[Ni(cyclam)]2[BPTC]}n (2) in the single-crystal-to-single-crystal manner. The X-ray crystal structure of 2 reveals extensive dynamic motions of the molecular components in response to guest removal, involving rotation of the carboxylate and macrocycle, swing of the biphenyl, and bending of the macrocyclic coordination plane toward the carboxylate plane, which reduces the interlayer distance