24 research outputs found
On a conjecture of Dekking : The sum of digits of even numbers
Let and denote by the sum-of-digits function in base . For
consider # \{0 \le n < N : \;\;s_q(2n) \equiv j \pmod q \}.
In 1983, F. M. Dekking conjectured that this quantity is greater than
and, respectively, less than for infinitely many , thereby claiming an
absence of a drift (or Newman) phenomenon. In this paper we prove his
conjecture.Comment: 6 pages, accepted by JTN
Effective equidistribution of primitive rational points on expanding horospheres
We prove an effective version of a result due to Einsiedler, Mozes, Shah and
Shapira who established the equidistribution of primitive rational points on
expanding horospheres in the space of unimodular lattices in at least
dimensions. Their proof uses techniques from homogeneous dynamics and relies in
particular on measure-classification theorems --- an approach which does not
lend itself to effective bounds. We implement a strategy based on spectral
theory, Fourier analysis and Weil's bound for Kloosterman sums in order to
quantify the rate of equidistribution for a specific horospherical subgroup in
any dimension. We apply our result to provide a rate of convergence to the
limiting distribution for the appropriately rescaled diameters of random
circulant graphs.Comment: 21 pages, incorporates the referee's comments and correction
Multivariate normal distribution for integral points on varieties
Given a variety over , we study the distribution of the number of primes dividing the coordinates as we vary an integral point. Under suitable assumptions, we show that this has a multivariate normal distribution. We generalise this to more general Weil divisors, where we obtain a geometric interpretation of the covariance matrix. For our results we develop a version of the Erd\H{o}s-Kac theorem that applies to fairly general integer sequences and does not require a positive exponent of level of distribution
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified