Additional file 1 of Mendelian randomization analysis suggests no causal influence of gastroesophageal reflux disease on the susceptibility and prognosis of idiopathic pulmonary fibrosis

Additional file 1

Three 3D Lanthanide–Organic Frameworks Based on Novel Flexible Multicarboxylates: From ssa to rtl Topologies

Three lanthanide–organic frameworks have been solvothermally synthesized and characterized. Complex 1 {[Pr2(bbda)(OH)2(H2O)6]·12H2O}n (H4bbda = 5,5′-(2,4,6-trimethyl-1,3-phenylene)bis(methylene)bis(oxy)diisophthalic acid) is a 3D porous framework belonging to a 2-nodal net with the ssa topology. The coordinated formate ligand from in situ hydrolyzation of dmf binds metal centers to generate rigid rod-shaped SBUs (secondary building units) in both complexes 2 and 3, [Ln(HCOO)(L1)(dmf)]n (Ln = Er (2), Tm (3), H2L1 = 2,2′-(2,3,5,6-tetramethyl-1,4-phenylene) bis(methylene)bis(sulfanediyl)dibenzoic acid, dmf = N,N′-dimethylformamide). The flexible ligand H4bbda in complex 1 exhibits syn conformation, while the flexible ligand H2L1 in complexes 2 and 3 adopts anti conformation. The anti L1 ligand links the rod-shaped SBUs to give 2 and 3 3D network with the rtl topology

Three 3D Lanthanide–Organic Frameworks Based on Novel Flexible Multicarboxylates: From ssa to rtl Topologies

Three lanthanide–organic frameworks have been solvothermally synthesized and characterized. Complex 1 {[Pr2(bbda)(OH)2(H2O)6]·12H2O}n (H4bbda = 5,5′-(2,4,6-trimethyl-1,3-phenylene)bis(methylene)bis(oxy)diisophthalic acid) is a 3D porous framework belonging to a 2-nodal net with the ssa topology. The coordinated formate ligand from in situ hydrolyzation of dmf binds metal centers to generate rigid rod-shaped SBUs (secondary building units) in both complexes 2 and 3, [Ln(HCOO)(L1)(dmf)]n (Ln = Er (2), Tm (3), H2L1 = 2,2′-(2,3,5,6-tetramethyl-1,4-phenylene) bis(methylene)bis(sulfanediyl)dibenzoic acid, dmf = N,N′-dimethylformamide). The flexible ligand H4bbda in complex 1 exhibits syn conformation, while the flexible ligand H2L1 in complexes 2 and 3 adopts anti conformation. The anti L1 ligand links the rod-shaped SBUs to give 2 and 3 3D network with the rtl topology

Phase relationship between EAWM and EASM at 100-year (a) and 31-year (b) time scales.

<p>Phase relationship between EAWM and EASM at 100-year (a) and 31-year (b) time scales.</p

Uncoordinated Hexafluorosilicates in a Microporous Metal–Organic Framework Enabled C₂H₂/CO₂ Separation

Metal–organic frameworks (MOFs) represent a kind of low-energy physisorbent with modifiable pores and framework structures; however, a deep understanding of how these structural features influence properties is a prerequisite for the rational design and development of tailor-made materials for advanced applications. In this report, a MOF, [Ni2(TCPP-Ni)1/4(TPIM)2(COOH)­F]­[(Me2NH2)­SiF6]·xS (SDU-CP-1; S = solvent molecules, SDU = Shandong University, and CP = coordination polymer), assembled by tetrakis­(4-carboxyphenyl)­porphyrin (TCPP-Ni) and 2,4,5-tris­(4-pyridyl)­imidazole (TPIM) ligands as well as Ni2+ cations is reported. Interestingly, inorganic SiF62– anions do not serve as the pillars like precedents in the framework but are just counterions, which endows SDU-CP-1 with high uptake for C2H2 and adsorption selectivity (2.5–4.2) for C2H2/CO2 at room temperature, as certified by gas adsorption and separation experiments and grand canonical Monte Carlo calculation

East Asian Monsoon Signals Reflected in Temperature and Precipitation Changes over the Past 300 Years in the Middle and Lower Reaches of the Yangtze River

<div><p>Based on observational data and Asian monsoon intensity datasets from China, the relationships between the East Asian winter monsoon index and winter temperature, the East Asian summer monsoon index and Meiyu precipitation over the middle and lower reaches of the Yangtze River, were analyzed. We found that the monsoon signals were reflected in the temperature and Meiyu precipitation variations. Thus, we used the reconstructed Meiyu precipitation and winter temperature series for the past 300 years and detected the summer/winter monsoon intensity signals using multi-taper spectral estimation method and wavelet analysis. The main periodicities of Meiyu precipitation and winter temperature, such as interannual cycle with 2–7-year, interdecadal-centennial cycles with 30–40-year and 50–100-year, were found. The good relationships between the East Asian summer and winter monsoons suggested that they were in phase at 31-year cycle, while out of phase at 100-year cycle, but with 20-year phase difference. In addition, the winter monsoon intensity may be regulated by the North Atlantic Oscillation, the Arctic Oscillation and the Atlantic Multidecadal Oscillation, and the summer monsoon is closely related to the signal intensities of the Pacific Decadal Oscillation.</p></div

Variations of EAWM and EASM over the interdecadal–centennial scale: (a) EAWM and (b) EASM.

<p>Variations of EAWM and EASM over the interdecadal–centennial scale: (a) EAWM and (b) EASM.</p

Highly Water-Stable Zn₅ Cluster-Based Metal–Organic Framework for Efficient Gas Storage and Organic Dye Adsorption

The development of multi-functional materials as physical adsorbents for gas storage and dye adsorption is of utmost importance for ecological environment management. Ionic metal–organic frameworks (MOFs) with exchangeable counterions would easily be modified to enhance their performance. Herein, we report a novel {Zn5}-based MOF (SDU-CP-2) with the dimethylamine cation [(CH3)2NH2]+ in its crystal structure, which can be readily exchanged with Li+ ions and cationic dyes. Consequently, it exhibits high CO2 and C2H2 adsorption capacities as well as charge/size-selective adsorption of dye molecules. The adsorption of SDU-CP-2 toward cationic dyes was confirmed to be efficient in terms of recyclability and ion-exchange mechanisms. The column filler experiment and high water stability decisively supported its potential application in waste water treatment

Relationship between EAWM, NAO, AO and AMO at 50–100-year cycles, AO and AMO use the green and red color axes (a), and EASM and PDO at 30–40-year cycles (b).

<p>Relationship between EAWM, NAO, AO and AMO at 50–100-year cycles, AO and AMO use the green and red color axes (a), and EASM and PDO at 30–40-year cycles (b).</p

Correlations between East Asian monsoon indices and temperature/precipitation during the observed period.

<p>(a) winter monsoon index and winter temperature and (b) summer monsoon index and June–July precipitation. The shaded areas from red to yellow passed negative correlation at 99%, 95%, 90% confidence levels, and green color indicates positive correlated regions.</p