A subduction-related metasomatically enriched mantle origin for the Luoboling and Zhongliao Cretaceous granitoids from South China: implications for magma evolution and Cu–Mo mineralization

<div><p>The Luoboling granodiorite porphyry and Zhongliao porphyritic biotite-granodiorite occur within the Zijinshan ore field in Fujian Province, southeast China. LA–ICP–MS zircon U–Pb dating yields ages of 103.1 ± 1.1 Ma (2σ, MSWD = 3.1) and 95.9 ± 0.6 Ma (2σ, MSWD = 1.2) for the Luoboling and Zhongliao intrusions, respectively. All rocks show high SiO₂, K₂O, and light rare earth element levels, variable CaO and Fe₂O₃^T, but low heavy rare earth element and high field strength element (Nb, Ta, Ti) concentrations. They also exhibit uniform initial ⁸⁷Sr/⁸⁶Sr ratios (0.7064–0.7068) and ε_Nd(t) values (−4.0 to −2.6), falling within the compositional field of Cretaceous basalts and mafic dikes in the Cathaysia Block. Together with their relatively high Hf isotopic ratios (ε_Hf(t) = −5.8 to +0.7), these data suggest that the Luoboling and Zhongliao intrusions were derived from a subduction-enriched mantle source. We infer fractional crystallization processes involving early fractionation of clinopyroxene and olivine, and subsequent fractionation of garnet forming the Luoboling granodiorite porphyry, eventually followed by amphibole- and biotite-dominated crystallization, with minor accessory mineral contribution, producing the (younger) Zhongliao porphyritic biotite-granodiorite. Asthenospheric mantle sources may have also contributed to generating the melts as indicated by initial Pb isotopic compositions and Hf isotopic compositions. The generation of these intrusions was associated with the Pacific subduction in an extensional setting during the Cretaceous.</p></div

Nature-Inspired One-Step Green Procedure for Enhancing the Antibacterial and Antioxidant Behavior of a Chitin Film: Controlled Interfacial Assembly of Tannic Acid onto a Chitin Film

The final goal of this study was to develop antimicrobial food-contact materials based on a natural phenolic compound (tannic acid) and chitin, which is the second most abundant polysaccharide on earth, using an interfacial assembly approach. Chitin film has poor antibacterial and antioxidant ability, which limits its application in industrial fields such as active packaging. Therefore, in this study, a novel one-step green procedure was applied to introduce antibacterial and antioxidant properties into a chitin film simultaneously by incorporation of tannic acid into the chitin film through interfacial assembly. The antibacterial and antioxidant behavior of chitin film has been greatly enhanced. Hydrogen bonds and hydrophobic interaction were found to be the main driving forces for interfacial assembly. Therefore, controlled interfacial assembly of tannic acid onto a chitin film demonstrated a good way to develop functional materials that can be potentially applied in industry

Additional file 2: Table S1. of The genetic variants in 3’ untranslated region of voltage-gated sodium channel alpha 1 subunit gene affect the mRNA-microRNA interactions and associate with epilepsy

Genetic variants and alleles in 3'UTR of SCN1A_v001 of male patients and controls (in *.ped file); Table S2. genetic variants and alleles in 3'UTR of SCN1A_v001 of female patients and controls (in *.ped file); Table S3. genetic variants in 3'UTR-SCN1A found in study subjects and their locations (in *.info file); Table S4. Fisher’s exact test on rare genetic variants for case/control association study; Table S5. 50 most expressed miRNA in four parts of CNS; Table S6. STarMir parameters of predicted miRNA-binding sites of 3’UTR of SCN1A gene in genotype groups; Table S7. the frequently lost and compensatory sites for the alteration in conserved sites of miRNAs binding of 3’UTR-SCN1A in genotype groups. Table S8. the conserved sites of miRNA binding in wild type 3’UTR-SCN1A. Table S9. the comparison of STarMir parameters between males and females. “S0”-“S14.txt” were the working input files for STarMir analysis. S0. wild type (reference) 3’UTR sequence; S1. male CTTTA haplotype 3’UTR sequence; S2. male CTCTA haplotype 3’UTR sequence; S3. male CCTTA haplotype 3’UTR sequence; S4. male TTTTA haplotype 3’UTR sequence; S5. female CTTAACA haplotype 3’UTR sequence; S6. female TTCAACA haplotype 3’UTR sequence; S7. female TTTAACA 3’UTR sequence; S8. female 6568_6571del 3’UTR sequence; S9. female 7338_7344del 3’UTR sequence; S10. female 7065_7066insG 3’UTR sequence; S11. 50 microRNAs expressed in human hippocampus; S12. 50 microRNAs expressed in human frontal cortex; S13. 50 microRNAs expressed in human cerebellum; S14. 50 microRNAs expressed in human midbrain. (ZIP 403 kb

Review of Alkali-Based Pretreatment To Enhance Enzymatic Saccharification for Lignocellulosic Biomass Conversion

Lignocelluloses have been the focus of much attention, because of their conversion to fermentable sugars for cellulosic ethanol production, both from the viewpoint of energy and the environment. Pretreatment plays a crucial rule in biomass conversion, to overcome the chemical and structural difficulties, which have evolved in lignocelluloses, and to produce a cost-effective fermentable sugar via enzymatic saccharification. Among the developed pretreatment approaches, alkali-based pretreatment technology, which can utilize the equipment and chemical recovery system in the pulping industry, has been considered one of the most promising pretreatment methods, mainly because of its high efficiency in delignification and high final total sugar yields. This paper reviews the classification, mechanism, advantages, disadvantages, and the progress of alkali-based pretreatment technologies, in order to better understand the fundamental principles of alkali-based pretreatments. This is of vital importance for the process improvement and commercial production of alkali-based pretreatment for producing cellulosic ethanol

Pretreatment of Corn Stover with the Modified Hydrotropic Method To Enhance Enzymatic Hydrolysis

Hydrotropic pretreatment using sodium xylene sulfonate (SXS) could remove lignin and xylan from corn stover to enhance enzymatic saccharification. Peracetic acid (PAA) treatment prior to the hydrotropic process [so-called modified hydrotropic pretreatment (MHP)] could double the delignification efficiency and remarkably increase glucan conversion. After pretreatment, samples were treated by PFI refining for comparison. With the supplement of PFI refining before enzymatic hydrolysis of the MHP-treated corn stover, 87.6% of the glucan yield could be achieved and the corresponding xylan yield was 43.7%. In addition, the pretreated corn stover was analyzed by Fourier transform infrared spectroscopy (FTIR), X-ray diffractometer (XRD), and scanning electron microscopy (SEM). The lignin precipitate from the spend liquor was also investigated by FTIR. The cleavage of the lignin structure could be observed from FTIR results. The crystallinity index (CrI) of corn stover after MHP was increased according to XRD analysis, while the reduction of total CrI of cellulose between pretreatment samples was analyzed by FTIR. SEM analysis demonstrated that PAA treatment affected the morphology of corn stover fiber by generating pores and allowing for better contact of the enzyme to polysaccharides

Synthesis of Cinnolines and Cinnolinium Salt Derivatives by Rh(III)-Catalyzed Cascade Oxidative Coupling/Cyclization Reactions

A novel method for the synthesis of cinnolines and cinnolinium salt derivatives via Rh­(III)-catalyzed cascade oxidative coupling/cyclization reaction from Boc-arylhydrazines and alkynes has been developed. The reactions have a broad substrate scope and high stereoselectivity with readily available starting materials and provides an efficient synthetic route for this kind of compounds. A catalytically competent five-membered rhodacycle has been isolated, thus revealing a key intermediate in the catalytic cycle

Least-squares fits of velocity distribution function to measured data.

<p>Least-squares fits of velocity distribution function to measured data.</p

Comparison of one-dimensional velocity distribution at 70% D.

<p>Comparison of one-dimensional velocity distribution at 70% D.</p

Regiodivergent Access to Five- and Six-Membered Benzo-Fused Lactams: Ru-Catalyzed Olefin Hydrocarbamoylation

We report herein a new strategy of the Ru-catalyzed intramolecular olefin hydrocarbamoylation for the regiodivergent synthesis of five- and six-membered benzo-fused lactams starting from <i>N</i>-(2-alkenylphenyl)­formamides. Using a combined catalyst of Ru₃(CO)₁₂/Bu₄NI in DMSO/toluene cosolvent (catalytic system A), a 5-<i>exo</i>-type cyclization proceeds favorably to form indolin-2-ones as a major product in good to excellent yield. When the reaction was conducted in the absence of halide additives in DMA/PhCl (catalytic system B), 3,4-dihydroquinolin-2-ones were obtained in major in moderate to high yield via a 6-<i>endo</i> cyclization process. An excellent level of regioselectivity was observed with a variety of substrates to deliver 5-<i>exo</i>- or 6-<i>endo</i>-cyclized lactams. It was found that while the selective cyclization was controlled primarily by the choice of catalytic systems employed, it was also greatly influenced by the structural nature of substrates. A halide-bridged trinuclear complex [Ru₃(CO)₁₀(μ₂-I)]⁻ is postulated to be an active species in the catalytic system A. Two reaction pathways are proposed, in which the Ru-catalyzed oxidative addition of formyl C–H or N–H bond initiates the subsequent cyclization processes

Rh(III)-Catalyzed C7-Thiolation and Selenation of Indolines

The rhodium­(III)-catalyzed intermolecular C7-thiolation and selenation of indolines with disulfides and diselenides were developed. This protocol relies on the use of a removable pyrimidyl directing group to access valuable C-7 functionalized indoline scaffolds with ample substrate scope and broad functional group tolerance