182 research outputs found

    sj-pdf-1-imr-10.1177_03000605211057823 - Supplemental material for Severe and persistent facial nerve stimulation after cochlear implantation in a patient with cochlear–facial dehiscence: a case report

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    Supplemental material, sj-pdf-1-imr-10.1177_03000605211057823 for Severe and persistent facial nerve stimulation after cochlear implantation in a patient with cochlear–facial dehiscence: a case report by Jingyuan Chen, Biao Chen, Lifang Zhang and Yongxin Li in Journal of International Medical Research</p

    Comparison of the electromagnetic force between the calculations results with the experimental results at different working air gap between the outer armature and the iron core.

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    Comparison of the electromagnetic force between the calculations results with the experimental results at different working air gap between the outer armature and the iron core.</p

    Organic Photocatalyzed Polyacrylamide without Heterogeneous End Groups: A Mechanistic Study

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    Photopolymerization reactions exhibit distinctive advantages over traditional, thermally initiated polymerization, such as better temporal controls, faster kinetics, and solvent-free conditions. However, most photopolymerizations employ a combination of photochemically labile molecules as sensitizers and initiators, which are inevitably covalently incorporated into the polymer products as end groups, with unknown influences on the mechanical, biological, and environmental properties. Therefore, it is desirable to produce compositionally “pure” polymers with one single repeating unit. Here, we demonstrate that a commercially available monomer N,N-dimethyl acrylamide (DMA) can be used to produce polyDMA (PDMA) homopolymers without heterogeneous end groups, which can be regulated by a cheap and commonly seen naphthalimide: the polymerization of DMA yields PDMA with high molecular weight, and nearly 100% monomer conversion could be achieved within 2 min under a UV light-emitting diode (λ = 365 nm), but was instantly terminated in the dark. To understand the mechanism of such dramatic light/dark switching behaviors of the system, we propose a plausible catalytic cycle that is supported by theoretical calculations and experiments: using a nonpolymerizable aliphatic amine as a model compound, we infer that DMA and naphthalimide may form a “UV-activated complex”, captured by high-resolution mass spectrometry, before it dissociates into an unstable DMA radical cation to initiate the polymerization and a stable NCP radical anion, which can be analyzed with NMR and electron paramagnetic resonance spectroscopically under argon at room temperature

    The effect of working air gap on the deviation between the tested electromagnetic force of electromagnet with variable pole area and the tested electromagnetic force of planar pole electromagnet.

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    The effect of working air gap on the deviation between the tested electromagnetic force of electromagnet with variable pole area and the tested electromagnetic force of planar pole electromagnet.</p

    Angular deviation and diffraction efficiency of Littrow-configuration ECDL for three-dimensional diffraction

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    We consider in this paper the angular deviation and diffraction efficiency of the reflection gratings in Littrow-configuration for applications of external cavity diode laser (ECDL) using the rigorous coupled-wave analysis (RCWA) method. We consider the three-dimensional diffraction case in general, where the incidence plane is un-parallel with the grating vector (i.e. conical diffraction). The angular tolerance of arbitrary gratings under plane and conical diffraction are thus derived and presented. A typical blazed grating is chosen as an example to calculate its diffraction efficiency (DE) using RCWA. {Furthermore}, we point out that the angular tolerance and reflection efficiency can be improved if the appropriate parameter settings are selected for Littrow-configuration ECDL, including incidence angle, diffraction order, grating period and blazed angle. Otherwise, a tiny slanting angle of the grating vector deviated from the incidence plane will {deviate the feedback light away from} entering the LD-chip and halt laser oscillation in the external cavity. Finally, a general rule for the parameter settings in Littrow-configuration is provided as a benchmark

    Equivalent magnetic circuit of electromagnet with variable pole area.

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    Equivalent magnetic circuit of electromagnet with variable pole area.</p

    Comparison of the electromagnetic force between the calculations results with the experimental results at different working air gap between the outer armature and the iron core.

    No full text
    Comparison of the electromagnetic force between the calculations results with the experimental results at different working air gap between the outer armature and the iron core.</p

    PFOA/PFOS Facilitated Intestinal Fatty Acid Absorption by Activating the PPARα Pathway: Insights from Organoids Model

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    Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) continue to be extensively present in the natural environment and seriously threaten human health. The intestinal tract is the primary organ of PFOA/PFOS exposure due to the consumption of contaminated food and drinking water. However, it remains unclear how PFOA/PFOS affects intestinal function and overall health. The aim of this study was to investigate the influence of PFOA/PFOS on the absorption of fatty acids in the intestine and the underlying mechanisms using three-dimensional (3D) intestinal organoids. Our results showed that PFOS, but not PFOA, could significantly enhance the fatty acid uptake capacity without obvious damage to the organoids. Furthermore, PFOS markedly reduced the protein levels of ChgA in enteroendocrine cells, but with no observed impact on aldolase B+ enterocytes. Mechanistically, exposure to PFOS induced the activation of the peroxisome proliferator-activated receptor (PPAR) α pathway in intestinal organoids, with enhanced expression of PPARα target genes associated with fatty acid metabolism, such as Fabp1 and Cd36 (fatty acid transporter genes), Acox1 and Pdk4 (fatty acid oxidation genes), and Plin2 and Plin3 (lipid droplet synthesis genes). These data suggest that PFOS have the potential to affect the absorption function of the intestinal epithelium through the PPARα pathway, and its effect is much stronger than that of PFOA. Our findings also highlight that organoids can be used as a valuable model for conducting toxicological research on environmental chemicals

    The influence of working air gap on the deviation between the tested electromagnetic force of electromagnet with variable pole area and the tested electromagnetic force of planar pole electromagnet.

    No full text
    The influence of working air gap on the deviation between the tested electromagnetic force of electromagnet with variable pole area and the tested electromagnetic force of planar pole electromagnet.</p
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