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Water for agriculture: implications for future policy and practice
Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas
‘The central focus of my life’: Roselands and Youth Culture in the 1960s
This article explores aspects of the early history of Roselands, a large regional shopping centre built in the municipality of Canterbury in the early 1960s. Evidence is drawn from archival and media sources, as well as an online survey designed to capture the recollections of Sydney residents about the city’s shopping centre history. The article explores the ways in which local youth engaged with the shopping centre, what it meant to them and how they used it. The article further considers how the evidence of this usage might make us reimagine the shopping centre itself, arguing that despite their sheer facades and interiority there is a degree of porousness between local communities and major retail developments
Quantifying Operational Constraints of Low-Latency Telerobotics for Planetary Surface Operations
NASA's SLS and Orion crew vehicle will launch humans to cislunar space to
begin the new era of space exploration. NASA plans to use the Orion crew
vehicle to transport humans between Earth and cislunar space where there will
be a stationed habitat known as the Deep Space Gateway (DSG). The proximity to
the lunar surface allows for direct communication between the DSG and surface
assets, which enables low-latency telerobotic exploration. The operational
constraints for telerobotics must be fully explored on Earth before being
utilized on space exploration missions. We identified two constraints on space
exploration using low-latency surface telerobotics and attempts to quantify
these constraints. A constraint associated with low-latency surface
telerobotics is the bandwidth available between the orbiting command station
and the ground assets. The bandwidth available will vary during operation. As a
result, it is critical to quantify the operational video conditions required
for effective exploration. We designed an experiment to quantify the threshold
frame rate required for effective exploration. The experiment simulated
geological exploration via low-latency surface telerobotics using a COTS rover
in a lunar analog environment. The results from this experiment indicate that
humans should operate above a threshold frame rate of 5 frames per second. In a
separate, but similar experiment, we introduced a 2.6 second delay in the video
system. This delay recreated the latency conditions present when operating
rovers on the lunar farside from an Earth-based command station. This time
delay was compared to low-latency conditions for teleoperation at the DSG
(0.4 seconds). The results from this experiment show a 150% increase in
exploration time when the latency is increased to 2.6 seconds. This indicates
that such a delay significantly complicates real-time exploration strategies.Comment: 10 pages, 8 figures, Proceedings of the IEEE Aerospace Conference,
Big Sky, MT. arXiv admin note: text overlap with arXiv:1706.0375
The Efficacy of Administering Fruit-Derived Polyphenols to Improve Health Biomarkers, Exercise Performance and Related Physiological Responses
open access articlePolyphenols are secondary metabolites involved in a myriad of critical processes in plants. Over recent decades, special attention has been paid to the anti-oxidative role of fruit-derived polyphenols in the human diet, with evidence supporting the contribution of polyphenols in the prevention of numerous non-communicable disease outcomes. However, due to the low concentration in biological fluids in vivo, the antioxidant properties of polyphenols seem to be related to an enhanced endogenous antioxidant capacity induced via signaling through the nuclear respiratory factor 2 pathway. Polyphenols also seem to possess anti-inflammatory and antioxidant properties and have been shown to enhance vascular function via nitric oxide mediated mechanisms. Consequently, there is rationale to support fruit-derived polyphenol supplementation to enhance exercise performance, possibly via improved muscle perfusion. Fruit-derived polyphenol supplementation in exercise studies have included a variety of fruits, e.g., New Zealand blackcurrant, pomegranate, and cherry, in the form of extracts (multicomponent or purified), juices and infusions to varying degrees of benefit. For example, research has yet to link the health-related benefits of black elderberry (Sambucus nigra L.) ingestion to exercise performance in spite of the purported health benefits associated with black elderberry provision in vitro and in vivo models, which has been attributed to their high antioxidant capacity and polyphenol content. This review summarizes the existing evidence supporting a beneficial effect of fruit-derived polyphenols on various biological processes and outlines the potential for black elderberry ingestion to improve nitric oxide production, exercise performance, and the associated physiological responses before-, during- and post-exercise
Climate change at the ecosystem scale: a 50-year record in New Hampshire
Observing the full range of climate change impacts at the local scale is difficult. Predicted rates of change are often small relative to interannual variability, and few locations have sufficiently comprehensive long-term records of environmental variables to enable researchers to observe the fine-scale patterns that may be important to understanding the influence of climate change on biological systems at the taxon, community, and ecosystem levels. We examined a 50-year meteorological and hydrological record from the Hubbard Brook Experimental Forest (HBEF) in New Hampshire, an intensively monitored Long-Term Ecological Research site. Of the examined climate metrics, trends in temperature were the most significant (ranging from 0.7 to 1.3 °C increase over 40–50 year records at 4 temperature stations), while analysis of precipitation and hydrologic data yielded mixed results. Regional records show generally similar trends over the same time period, though longer-term (70–102 year) trends are less dramatic. Taken together, the results from HBEF and the regional records indicate that the climate has warmed detectably over 50 years, with important consequences for hydrological processes. Understanding effects on ecosystems will require a diversity of metrics and concurrent ecological observations at a range of sites, as well as a recognition that ecosystems have existed in a directionally changing climate for decades, and are not necessarily in equilibrium with the current climate
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