27 research outputs found

    Two-way sensitivity analysis results showing the impact of changes in the level of adherence to primaquine regimens.

    Full text link
    <p>Green represents disability-adjusted life-years (DALYs) averted by the screening strategy for a cohort of 1000 individuals. For costs, yellow indicates increased costs and blue indicates cost savings for the screening strategy for one individual. For net monetary benefit (<i>NMB</i>), purple indicates scenarios where the screening strategy would be cost-effective at a threshold of US$500 (<i>T</i>) where <i>NMB = T × ΔDALYs– ΔCosts</i>.</p

    One-way sensitivity analysis results on costs and disability-adjusted life-years (DALYs) for the comparison of the screening strategy with the chloroquine strategy in males.

    Full text link
    <p>The ranges used are specified in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0005602#pntd.0005602.t002" target="_blank">Table 2</a>. See <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0005602#pntd.0005602.s003" target="_blank">S3 Appendix</a> for all one-way sensitivity analysis results.</p

    The table shows simulated outcomes for 1000 <i>P</i>. <i>vivax</i> malaria patients of undetermined G6PD status at attendance, if they were managed according to each of three strategies (chloroquine, primaquine and screening) according to G6PD status, treatment given and the test result if screened.

    Full text link
    <p>The table shows simulated outcomes for 1000 <i>P</i>. <i>vivax</i> malaria patients of undetermined G6PD status at attendance, if they were managed according to each of three strategies (chloroquine, primaquine and screening) according to G6PD status, treatment given and the test result if screened.</p

    Map of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%), Scenario 2 (tafenoquine for all, primaquine adherence 66.7%), Scenario 3 (tafenoquine for adults, high primaquine adherence of 90%), and Scenario 4 (tafenoquine for adults, low primaquine adherence of 30%), compared to baseline (7 day low-dose primaquine (0.5 mg/kg), adherence set at comparison scenario).

    Full text link
    The municipality of Manaus is plotted using results for peri-urban Manaus. The ICER for the municipality of Caapiranga for Scenario 3 was US$60,273, well above the scale. Municipalities where a strategy increased DALYs as compared to baseline are shown in grey. Maps generated with shapefiles from the R package malariaAtlas (available from: https://cran.r-project.org/web/packages/malariaAtlas/index.html).</p
    corecore