Adaptive channel selection in IEEE 802.15.4 TSCH networks

Additional files 6: Table S5. Four conjugative transposon gene clusters in the Chryseobacterium indologenes J31 genome

シベリア亜寒帯林における樹冠と林床の植生指数

Clinical characteristic of patients with rheumatoid arthritis (RA) and trauma. (DOC 45 kb

Synthesis and Characterization of Cleavable Core-Cross-Linked Micelles Based on Amphiphilic Block Copolypeptoids as Smart Drug Carriers

Amphiphilic block copolypeptoids consisting of a hydrophilic poly­(<i>N</i>-ethyl glycine) segment and a hydrophobic poly­[(<i>N</i>-propargyl glycine)-<i>r</i>-(<i>N</i>-decyl glycine)] random copolymer segment [PNEG-<i>b</i>-P­(NPgG-<i>r</i>-NDG), EPgD] have been synthesized by sequential primary amine-initiated ring-opening polymerization (ROP) of the corresponding <i>N</i>-alkyl <i>N</i>-carboxyanhydride monomers. The block copolypeptoids form micelles in water and the micellar core can be cross-linked with a disulfide-containing diazide cross-linker by copper-mediated alkyne–azide cycloaddition (CuAAC) in aqueous solution. Transmission electron microscopy (TEM) and dynamic light scattering (DLS) analysis revealed the formation of spherical micelles with uniform size for both the core-cross-linked micelles (CCLMs) and non-cross-linked micelles (NCLMs) precursors for selective block copolypeptoid polymers. The CCLMs exhibited increased dimensional stability relative to the NCLMs in DMF, a nonselective solvent for the core and corona segments. Micellar dissociation of CCLMs can be induced upon addition of a reducing agent (e.g., dithiothreitol) in dilute aqueous solutions, as verified by a combination of fluorescence spectroscopy, size exclusion chromatography (SEC), and ¹H NMR spectroscopic measurement. Doxorubicin (DOX), an anticancer drug, can be loaded into the hydrophobic core of CCLMs with a maximal 23% drug loading capacity (DLC) and 37% drug loading efficiency (DLE). <i>In vitro</i> DOX release from the CCLMs can be triggered by DTT (10 mM), in contrast to significantly reduced DOX release in the absence of DTT, attesting to the reductively responsive characteristic of the CCLMs. While the CCLMs exhibited minimal cytotoxicity toward HepG2 cancer cells, DOX-loaded CCLMs inhibited the proliferation of the HepG2 cancer cells in a concentration and time dependent manner, suggesting the controlled release of DOX from the DOX-loaded CCLMS in the cellular environment

On-chip spectrometer using stratified waveguides filters

We present an ultra-compact single-shot spectrometer on silicon platform with broad operation bandwidth and high resolution. It consists of 32 stratified waveguide filters (SWFs) with diverse transmission spectra for sampling the unknown spectrum of the input signal and a specially designed ultra-compact structure for splitting the incident signal into 32 filters with low imbalance. Each SWF has a footprint less than 1um x 30um, while the 1x32 splitter and 32 filters in total occupy an area of about 35um x 260um, which to the best of our knowledge, is the smallest footprint spectrometer realized on silicon photonic platform. Experimental characteristics of the fabricated spectrometer demonstrate a broad operating bandwidth of 180nm centered at 1550nm and narrowband peaks with 0.45nm Full-Width-Half-Maximum (FWHM) can be clearly resolved. This concept can also be implemented using other material platforms for operation in optical spectral bands of interest for various applications

A photonic integrated circuits with reconfigurablenonreciprocal transmission and all-opticalfunctionalities

We present a photonics integrated circuit on silicon substrate withreconfigurable nonreciprocal transmission that exhibits a large isolationratio and low insertion loss. It also offers ability for all-optical function-alities, like optical computing gates, or a flip-flop. The circuit is a mixedcavity system of which the linear transmission can be tuned as a Fanoresonance or electromagnetically induced transparency (EIT) using twointegrated heaters. With high optical intensity inside the cavity, the Fanoresonance and EIT peak induce a strong distortion due to thermal non-linearities in the cavity, and these distortions depend on the transmissiondirection due to the asymmetric power distribution in the cavities. Theresulting large isolation ratio is attributed to the inherent sharp slope ofthe Fano resonance and the large extinction ratio of the EIT peak. Thus,a high-power forward-propagating signal will trigger the nonreciprocalphenomenon for low-loss transmission, while backward transmission willsee high loss irrespective of its power level, which is an outstanding im-provement upon previously reported nonlinearity induced nonreciprocityin silicon photonics. The reconfigurability of the high transmission direc-tion comes from the efficient control of the mode excitation and couplinginside the cavity using the integrated heaters. Also, by using a separatepump laser, the device could be developed for all-optical functions likeswitching, logic and computing

Data_Sheet_1_Genomic Differentiation and Demographic Histories of Two Closely Related Salicaceae Species.zip

Populus alba (P. alba) and Populus davidiana (P. davidiana) are important plant species for answering a variety of issues on species evolution due to their wide distribution and ability to adapt to a variety of environments and climates. Even though P. alba and P. davidiana belong to ecologically and economically important forest trees in the Northern Hemisphere, little is known about their genomic landscape and genome divergence during speciation. We re-sequenced 20 and 19 members of P. davidiana and P. alba, respectively, and found that the Dxy value between P. alba and P. davidiana was 0.2658, whereas the FST values were 0.2988, indicating that the genetic divergence was fairly clear. Populus davidiana and P. alba diverged from the ancestor in the middle Pleistocene, c. 0.80 Ma (95% HPD: 0.79–0.81 Ma). The population sizes of P. davidiana increased ~20,000 years ago after a considerable long-term decline following divergence. However, after differentiation, the effective population size of P. alba expanded slightly before experiencing a long-term bottleneck effect. According to the expectation of allopatric speciation, we found a significant number of genomic differentiation sites in both species' speciation events, and the majority of these genomic differentiation regions can be attributed to neutral evolutionary processes. Nevertheless, the regions with extreme divergence exist in abundance, indicating that natural selection has had an impact. Positive selection can be found in highly differentiated regions, while long-term balancing selection traits can be easily observed in low differentiated regions. According to these findings, climate differences over the Quaternary, as well as variance in linked selection and recombination, all contributed significantly to genomic divergence during allopatric speciation of the two aspens.</p

Synthesis of Five-Membered Cyclic Phosphinic Acids via the [4C+1P] Cyclization of 1,3-Dienes with a Combination of PBr₃ and P(OMe)₃ as the P^(III) Source

An efficient method for the synthesis of 1-hydroxy-2,5-dihydrophosphole 1-oxides, a type of five-membered P-containing heterocyclic compound, is presented. The reaction was carried out through a [4C+1P] cyclization of 1,3-dienes with a combination of PBr3 and P(OMe)3 as the P(III) source. To compare with the reported methods, the protocol reported herein not only is much milder and more rapid but also displays a broad substrate scope and affords the products in high yields (50–94%). In addition, the reaction could be reliably scaled up at the gram-scale level and was demonstrated to be a versatile platform for flexible derivatization. Consequently, this method provides a general and reliable way for the synthesis of five-membered phosphole derivatives

Results from regression with propensity score weighting describing associations between co-residence and mental health, by socio-demographic and parental characteristics, 2018.

Results from regression with propensity score weighting describing associations between co-residence and mental health, by socio-demographic and parental characteristics, 2018.</p

Table of covariates used in regression.

The growing trend towards young adults staying in the parental home has garnered much recent scholarly interest. However, less is known about which young adults are living at home, and the impacts this has over young adults’ lives. Using The Household, Income and Labour Dynamics in Australia (HILDA) dataset, this study examines the profiles of co-residing young adults and how these have changed over the first two decades of the 21st century. It then analyses the associations between co-residence and young adults’ mental health, applying a propensity score modelling approach to determine differences in mental health between young adults living at home and their counterparts living independently. Results indicate that rates of co-residence have increased over the 2000s, most steeply amongst those residing outside of major cities (by 46%), older adults (by 36%), females (by 28%), and low-income groups (by 10%). Findings show a significant negative association between co-residence and mental health (a 4-point difference on the 100-point scale, 95% CI -5.93, -2.14). However, the greatest differential in mental health between co-resident and independent young adults is observed amongst those for whom rates of co-residence have increased most dramatically, i.e., females and older adults (a 6-point difference in mental health) and residents of regional and rural areas (a 5-point difference in mental health). We situate this discussion in the context of intensifying housing market constraints, considering how the transformation of the Australian housing system into a vehicle for wealth accumulation has generated barriers to residential independence.</div

Parental socio-demographic and housing characteristics by young adults’ co-residence status, 2018, % (95% confidence intervals).

Parental socio-demographic and housing characteristics by young adults’ co-residence status, 2018, % (95% confidence intervals).</p