Visualization 1: Lock-in-detection-free line-scan stimulated Raman scattering microscopy for near video-rate Raman imaging

SRS video imaging on 1.0 µm PMMA beads acquired during Brownian motion in water. Originally published in Optics Letters on 01 September 2016 (ol-41-17-3960

Efficient and highly selective cyclization induced by Lewis acid to generate 2-hydroxyl-α-cyclogeraniol

<p>A cyclization reaction of the hydroxyl-protected geraniol epoxide induced by the different Lewis acids to generate 2-hydroxyl-α-cyclogeraniol has been explored. Compared with the previous methods, this method enhances the production and selectivity of this reaction without the consumption of a large amount of solvent. Also, the coordination of the metal with two oxygen atoms of hydroxyl groups might be crucial for the reaction is first addressed.</p

Visualization 2: Optical diagnosis and characterization of dental caries with polarization-resolved hyperspectral stimulated Raman scattering microscopy

3-D colocalized multimodal nonlinear microscopic images of dental caries Originally published in Biomedical Optics Express on 01 April 2016 (boe-7-4-1284

Visualization 1: Optical diagnosis and characterization of dental caries with polarization-resolved hyperspectral stimulated Raman scattering microscopy

3-D colocalized multimodal nonlinear microscopic images of DEJ in the tooth Originally published in Biomedical Optics Express on 01 April 2016 (boe-7-4-1284

Model Emulsions Stabilized with Nonionic Surfactants: Structure and Rheology Across Catastrophic Phase Inversion

The catastrophic phase inversion process of model emulsions (water/Span 80-Tween 80/heptane) from oil-in-water to water-in-oil emulsion was investigated. During this process, the phase inversion of the emulsion was monitored through Fourier transform infrared spectroscopy (FT-IR). In emulsions without NaCl, oil-in-water gel emulsions are formed prior to phase inversion. As the HLB value increases, the oil volume fraction required for phase inversion becomes higher. Polydisperse distribution of the gel emulsion is observed from microscope optical images. The Turbiscan Lab stability analyzer indicates that O/W gel emulsions before the phase inversion has good stability at 50 °C. Rheological measurements reveal that emulsions exhibit non-Newtonian behavior. The viscosity of the gel emulsions increases significantly prior to phase inversion. As the oil volume fraction increases, the storage modulus and loss modulus of the gel emulsion increase to a maximum, at which catastrophic phase inversion occurs. In emulsions with NaCl, there is no oil-in-water gel emulsion formed before phase inversion. The physicochemical properties of the emulsion play a crucial role in whether gel emulsions are produced during catastrophic phase inversion. These gel emulsions have the potential to diversify the applications in crude oil extraction, drug delivery systems, packaging materials, and other fields

Microwave Assisted Tandem Heck–Sonogashira Reactions of <i>N,N</i>-Di-Boc-Protected 6‑Amino-5-iodo-2-methyl Pyrimidin-4-ol in An Efficient Approach to Functionalized Pyrido[2,3‑<i>d</i>]Pyrimidines

A microwave assisted tandem Heck–Sonogashira cross-coupling reaction between 6-<i>N,N</i>-di-Boc-amino-5-iodo-2-methyl pyrimidin-4-ol and various aryl alkynyl substrates has been developed. This process generates novel 5-enynyl substituted pyrimidines, which can be transformed to novel functionalized pyrido­[2,3-<i>d</i>]­pyrimidines by way of a silver catalyzed cyclization reaction

Enterovirus detection in water vs. shellfish at 9 sampling locations.

<p>Enterovirus detection in water vs. shellfish at 9 sampling locations.</p

PCR Condition brackets included in optimization assay.

a<p>40-50°C was included if reported T_anneal in literature was <50°C.</p

Enterovirus detection in Hawaiian environmental waters.

a<p>See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032442#pone-0032442-g001" target="_blank">Figure 1</a>.</p

Environmental sampling sites around the island of O’ahu, Hawaii.

<p>Environmental sampling sites around the island of O’ahu, Hawaii.</p