Summary receiver operating characteristic curve of 16S rRNA gene PCR diagnostic value in bloodstream infections.

<p>Summary receiver operating characteristic curve of 16S rRNA gene PCR diagnostic value in bloodstream infections.</p

Flow chart of selection process for eligible studies.

<p>Flow chart of selection process for eligible studies.</p

Summary of subgroup analysis of the included studies by different study characteristics.

<p>CI, confidence interval; PLR, positive likelihood ratio; NLR, negative likelihood ratio; DOR, diagnostic odds ratio; AUC area under the curve; Q*, Q point value.</p><p>Summary of subgroup analysis of the included studies by different study characteristics.</p

Risk of bias and applicability concerns graph.

<p>Review authors' judgments about each domain presented as percentages across included studies.</p

Funnel graph for the assessment of potential publication bias of the 28 included studies.

<p>Funnel graph for the assessment of potential publication bias of the 28 included studies.</p

Diagnostic Odds Ratio with Cochran-Q value.

<p>Diagnostic Odds Ratio with Cochran-Q value.</p

Forest plots for the diagnostic accuracy of 16S rRNA gene PCR.

<p>A. Sensitivity; B. Specificity; C. Positive likelihood ratio; D. Negative likelihood ratio.</p

Risk of bias and applicability concerns summary.

<p>Review authors' judgments about each domain for each included study.</p

Characteristics of the studies included in the meta-analysis.

<p>TP, true positive; FP, false positive; FN, false negative; TN, true negative; CSF, cerebrospinal fluid; PCR, polymerase chain reaction; FQ-PCR, fluorescent quantitative polymerase chain reaction; RT-qPCR, reverse transcription-quantitative PCR; CP, Crossing Point; C_T, cycle threshold; bp, base pairs; NR, no report.</p><p>Characteristics of the studies included in the meta-analysis.</p