Supplementary document for Broadband Sb2Se3/CdS/ZnO photodetectors based on physical vapor deposition for color imaging applications - 6370152.pdf

Fig. S1-S6 mentioned in the maintext, and Material and Methods section

Table_4_Hyperchloremia Is Associated With Poorer Outcome in Critically Ill Stroke Patients.DOCX

Background and Purpose: This study aims to explore the cause and predictive value of hyperchloremia in critically ill stroke patients.Materials and Methods: We conducted a retrospective study of a prospectively collected database of adult patients with first-ever acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH) admitted to the neurointensive care unit (NICU) of a university-affiliated hospital, between January 2013 and December 2016. Patients were excluded if admitted beyond 72 h from onset, if they required neurocritical care for less than 72 h, and were treated with hypertonic saline within 72 h or had creatinine clearance less than 15 mL/min.Results: Of 405 eligible patients, the prevalence of hyperchloremia ([Cl−] ≥ 110 mmol/L) was 8.6% at NICU admission ([Cl−]0) and 17.0% within 72 h ([Cl−]max). Thirty-eight (9.4%) patients had new-onset hyperchloremia and 110 (27.1%) had moderate increase in chloride (Δ[Cl−] ≥ 5 mmol/L; Δ[Cl−] = [Cl−]max − [Cl−]0) in the first 72 h after admission, which were found to be determined by the sequential organ failure assessment score in multivariate logistic regression analysis. Neither total fluid input nor cumulative fluid balance had significant association with such chloride disturbance. New-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl−] were both associated with increased odds of 30-day mortality and 6-month poor outcome, although no independent significance was found in multivariate models.Conclusion: Hyperchloremia tends to occur in patients more severely affected by AIS and ICH. Although no independent association was found, new-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl−] were related to poorer outcome in critically ill AIS and ICH patients.Subject terms: clinical studies, intracranial hemorrhage, ischemic stroke, mortality/survival, quality and outcomes.</p

Table_2_Hyperchloremia Is Associated With Poorer Outcome in Critically Ill Stroke Patients.DOCX

Background and Purpose: This study aims to explore the cause and predictive value of hyperchloremia in critically ill stroke patients.Materials and Methods: We conducted a retrospective study of a prospectively collected database of adult patients with first-ever acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH) admitted to the neurointensive care unit (NICU) of a university-affiliated hospital, between January 2013 and December 2016. Patients were excluded if admitted beyond 72 h from onset, if they required neurocritical care for less than 72 h, and were treated with hypertonic saline within 72 h or had creatinine clearance less than 15 mL/min.Results: Of 405 eligible patients, the prevalence of hyperchloremia ([Cl−] ≥ 110 mmol/L) was 8.6% at NICU admission ([Cl−]0) and 17.0% within 72 h ([Cl−]max). Thirty-eight (9.4%) patients had new-onset hyperchloremia and 110 (27.1%) had moderate increase in chloride (Δ[Cl−] ≥ 5 mmol/L; Δ[Cl−] = [Cl−]max − [Cl−]0) in the first 72 h after admission, which were found to be determined by the sequential organ failure assessment score in multivariate logistic regression analysis. Neither total fluid input nor cumulative fluid balance had significant association with such chloride disturbance. New-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl−] were both associated with increased odds of 30-day mortality and 6-month poor outcome, although no independent significance was found in multivariate models.Conclusion: Hyperchloremia tends to occur in patients more severely affected by AIS and ICH. Although no independent association was found, new-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl−] were related to poorer outcome in critically ill AIS and ICH patients.Subject terms: clinical studies, intracranial hemorrhage, ischemic stroke, mortality/survival, quality and outcomes.</p

Table_3_Hyperchloremia Is Associated With Poorer Outcome in Critically Ill Stroke Patients.DOCX

<p>Background and Purpose: This study aims to explore the cause and predictive value of hyperchloremia in critically ill stroke patients.</p><p>Materials and Methods: We conducted a retrospective study of a prospectively collected database of adult patients with first-ever acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH) admitted to the neurointensive care unit (NICU) of a university-affiliated hospital, between January 2013 and December 2016. Patients were excluded if admitted beyond 72 h from onset, if they required neurocritical care for less than 72 h, and were treated with hypertonic saline within 72 h or had creatinine clearance less than 15 mL/min.</p><p>Results: Of 405 eligible patients, the prevalence of hyperchloremia ([Cl⁻] ≥ 110 mmol/L) was 8.6% at NICU admission ([Cl⁻]₀) and 17.0% within 72 h ([Cl⁻]_max). Thirty-eight (9.4%) patients had new-onset hyperchloremia and 110 (27.1%) had moderate increase in chloride (Δ[Cl⁻] ≥ 5 mmol/L; Δ[Cl⁻] = [Cl⁻]_max − [Cl⁻]₀) in the first 72 h after admission, which were found to be determined by the sequential organ failure assessment score in multivariate logistic regression analysis. Neither total fluid input nor cumulative fluid balance had significant association with such chloride disturbance. New-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl⁻] were both associated with increased odds of 30-day mortality and 6-month poor outcome, although no independent significance was found in multivariate models.</p><p>Conclusion: Hyperchloremia tends to occur in patients more severely affected by AIS and ICH. Although no independent association was found, new-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl⁻] were related to poorer outcome in critically ill AIS and ICH patients.</p><p>Subject terms: clinical studies, intracranial hemorrhage, ischemic stroke, mortality/survival, quality and outcomes.</p

Table_1_Hyperchloremia Is Associated With Poorer Outcome in Critically Ill Stroke Patients.DOCX

<p>Background and Purpose: This study aims to explore the cause and predictive value of hyperchloremia in critically ill stroke patients.</p><p>Materials and Methods: We conducted a retrospective study of a prospectively collected database of adult patients with first-ever acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH) admitted to the neurointensive care unit (NICU) of a university-affiliated hospital, between January 2013 and December 2016. Patients were excluded if admitted beyond 72 h from onset, if they required neurocritical care for less than 72 h, and were treated with hypertonic saline within 72 h or had creatinine clearance less than 15 mL/min.</p><p>Results: Of 405 eligible patients, the prevalence of hyperchloremia ([Cl⁻] ≥ 110 mmol/L) was 8.6% at NICU admission ([Cl⁻]₀) and 17.0% within 72 h ([Cl⁻]_max). Thirty-eight (9.4%) patients had new-onset hyperchloremia and 110 (27.1%) had moderate increase in chloride (Δ[Cl⁻] ≥ 5 mmol/L; Δ[Cl⁻] = [Cl⁻]_max − [Cl⁻]₀) in the first 72 h after admission, which were found to be determined by the sequential organ failure assessment score in multivariate logistic regression analysis. Neither total fluid input nor cumulative fluid balance had significant association with such chloride disturbance. New-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl⁻] were both associated with increased odds of 30-day mortality and 6-month poor outcome, although no independent significance was found in multivariate models.</p><p>Conclusion: Hyperchloremia tends to occur in patients more severely affected by AIS and ICH. Although no independent association was found, new-onset hyperchloremia and every 5 mmol/L increment in Δ[Cl⁻] were related to poorer outcome in critically ill AIS and ICH patients.</p><p>Subject terms: clinical studies, intracranial hemorrhage, ischemic stroke, mortality/survival, quality and outcomes.</p

Detection of apoptosis in neonatal rat cardiomyocytes by flow cytometry.

<p>Bar graph of early (A and B) and late (C and D) apoptotic rate. All data were expressed as mean±SEM (<i>n</i> = 6). *<i>P</i><0.05 compared with control group; @<i>P</i><0.05 compared with model group; #<i>P</i><0.05 compared with model+GdCl3 group; &<i>P</i><0.05 compared with control group. Groups in A and C were control, model, model+GdCl3, model+NPS-2390+GdCl3, model+NPS-2390, and control+GdCl3. Groups in B and D were control, model, model+GdCl3, siRNA+model+GdCl3, nRNA+model, and siRNA+model. Glucose: 25.5 mM; GdCl3: 300 µM; NPS-2390: 10 µM.</p

CaSR protein expression determined by western blot analysis in diabetic rat hearts.

<p><b>(</b>A) Representative bands of CaSR in diabetic rat hearts. a, control; b, two months. (B) The data represent the mean±SEM of eight independent experiments. The intensity of each band was quantified using densitometry, and the data were normalized to band intensity of GAPDH used as internal control. *<i>P<</i>0.05 compared with control group.</p

Underwater Multispectral Computational Imaging Based on a Broadband Water-Resistant Sb₂Se₃ Heterojunction Photodetector

Exploration, utilization, and protection of marine resources are of great significance to the survival and development of mankind. However, currently classical optical cameras suffer information loss, low contrast, and color distortion due to the absorption and scattering nature for the underwater environment. Here, we demonstrate an underwater multispectral computational imaging system combined with single-photodetector imaging algorithm technology and a CdS/Sb2Se3 heterojunction photodetector. The computational imaging technology coupled with an advanced Fourier algorithm can capture a scene by a single photodetector without spatial resolution that avoids the need to rely on high-density detectors array and bulky optical components in traditional imaging systems. This convenient computational imaging method provides more flexible possibilities for underwater imaging and promises to give more imaging capabilities (such as multispectral imaging, antiscattering imaging capability) to meet ever-changing demand of underwater imaging. In addition, the water-resistant CdS/Sb2Se3 heterojunction photodetector fabricated by the close spaced sublimation (Sb2Se3) and chemical bath deposition (CdS) shows excellent self-powered photodetection performance at zero bias with high LDR of 128 dB, broadband response spectrum range of 300–1050 nm, high responsivity up to 0.47 A/W, and high specific detectivity over 5 × 1012 jones. Compared with the traditional optical imaging system, our designed computational imaging system that combines the advanced Fourier algorithm and a high-performance CdS/Sb2Se3 heterojunction photodetector exhibits outstanding antiscattering imaging capability (shielded by frosted glass), weak light imaging capability (∼0.2 μW/cm2, corresponding to moonlight intensity), and multispectral imaging capability. Therefore, we believe that this work will boost the progress of marine science

Flow cytometric analysis of apoptosis.

<p>A, 10,000 cells of each experiment were collected by flow cytometry and analyzed using Cell Quest software. Early apoptotic cells (annexin-V+ and PI-) were displayed in the lower right quadrant, and late apoptotic cells (annexin-V+ and PI+) were shown in the upper right quadrant. (A) Plots of sorted apoptotic cells. Apoptosis were evaluated after treating neonatal rat cardiomyocytes with 25.5 mM glucose, and staining with annexin-V and PI. Flow cytometry profile represents annexin-V-FITC staining in <i>x</i> axis and PI in <i>y</i> axis. The number represents the percentage of apoptotic cells in each condition. (B) Bar graph of cell apoptotic rate. All data were expressed as mean±SEM (<i>n</i> = 6). *<i>P</i><0.05 compared with control group.</p