7 research outputs found
Supplementary document for High-capacity MIMO visible light communication integrated into mini-LED LCDs - 6946279.pdf
Discussion of inter-symbol interference and inter-channel crosstal
Effects of β<sub>3</sub>-AR Abs on intracellular calcium transient ([Ca<sup>2+</sup>]<sub>iT</sub>) and I<sub>Ca-L</sub> in isolated adult rat cardiomyocytes.
<p>A. Representative [Ca<sup>2+</sup>]<sub>iT</sub> profile in isolated rat cardiomyocytes demonstrating decreased [Ca<sup>2+</sup>]<sub>iT</sub> induced by β<sub>3</sub>-AR Abs (0.1 μmol/L). B. Summary data (n=10, <sup>**</sup><i>P</i> < 0.01 <i>vs</i>. control.) C. Representative I<sub>Ca-L</sub> profile in isolated rat ventricular cardiomyocytes demonstrating inhibitory effects of β<sub>3</sub>-AR Abs (0.1 µmol/L) on I<sub>Ca-L</sub>. a. control; b. β<sub>3</sub>-AR Abs; c. after β<sub>3</sub>-AR Abs wash out. D. Group mean data demonstrating effects of β<sub>3</sub>-AR Abs (0.1 µmol/L) and BRL37344 (0.1 µmol/L) on I<sub>Ca-L</sub> in isolated rat ventricular cardiomyocytes. <sup>**</sup><i>P</i> < 0.01 <i>vs</i>. control. n=5.</p
β<sub>3</sub>-AR Abs from HF patients bound to β<sub>3</sub>-AR on the surface of H9c2 cells.
<p>A. The negative control. Nuclei were labeled with DAPI (blue). B. The positive control. Nuclei (blue), β<sub>3</sub>-AR was identified with anti-β<sub>3</sub>-AR antibody (Abcam, UK) (green). C. The experiment group. Nuclei (blue), β<sub>3</sub>-AR was identified with β<sub>3</sub>-AR Abs from HF patients (green).</p
Effects of β<sub>3</sub>-AR Abs on LV dilation and systolic function in AAB rats by echocardiography.
<div><p>A. M-mode echocardiography images from Sham-operated (Sham), 8wk post-AAB, and 8wk post-AAB treated with β<sub>3</sub>-AR Abs. B. C. β<sub>3</sub>-AR Abs prevented LV chamber dilation induced by AAB. D. E β<sub>3</sub>-AR Abs ameliorated LV systolic dysfunction induced by AAB. </p>
<p><sup>*</sup><i>P</i><0.05 <i>vs</i>. Sham-operated group, <sup>#</sup><i>P</i><0.05 <i>vs</i>. AAB group. Sham n=5, AAB n=5, AAB+β<sub>3</sub>-AR Abs n=8, AAB+Negative IgGs n=8.</p>
<p>FS: fractional shortening, EF: ejection fraction.</p></div
Negative inotropic effect of β<sub>3</sub>-AR Abs on isolated adult rat cardiomyocytes.
<p>A and B. Representative profiles of cell length and dL/dt. C. Negative inotropic agonist-like activities of β<sub>3</sub>-AR Abs (0.1 µmol/L, n=10) and the effects of nadolol, bupranolol, and β<sub>3</sub>-AR antigen upon β<sub>3</sub>-AR Abs-induced activities in isolated adult rat cardiomyocytes. (<sup>**</sup><i>P</i> < 0.01 <i>vs</i>. control, n=10).</p