Clustering analysis of genotyping data of B. cereus clinical endophthalmitis isolates.

<p>Phylogenetic tree of <i>B</i>. <i>cereus</i> clinical endophthalmitis isolates was drawn based on <i>vrrA</i> gene sequence analyses. The figure showed that <i>B</i>. <i>cereus</i> isolats could be grouped into three genotyping (GT) groups: GTI, GTII, and GTIII. GTI was be further divided into three subgroups.</p

Clinical manifestation and prognosis associated with three <i>vrrA</i>-based genotypes of <i>B</i>. <i>cereus</i>.

<p>Clinical manifestation and prognosis associated with three <i>vrrA</i>-based genotypes of <i>B</i>. <i>cereus</i>.</p

B-scan images of the patients' eyes infected with <i>B</i>. <i>cereus</i> before (A,B,C) and after (D,E,F) surgery operation.

<p>(A). Infection caused by GTI strains showed severe vitreous opacity (gay arrows). (B). Infection caused by GTII strains showed mild vitreous opacity (gray arrows). (C). Mild vitreous opacity infection caused by GTIII strains (gray arrow),high reflection and ascoustic shadow in vitreous showed foreign body (white arrow). (D). Infection caused by GTI strains after surgery. (E). Infection caused by GTII strains after surgery. (F). Infection caused by GTIII strains after surgery(the false expansion of eye ball after vitreous surgery with silicon oil tamponade).</p

Patients’ Information.

<p>Patients’ Information.</p

PCR amplification of the <i>vrrA</i> gene among clinical <i>B</i>. <i>cereus</i> isolates.

<p>Lane1-14: Bc1-Bc14; lane16-25: Bc16-Bc25; Lane26: <i>B</i>. <i>cereus</i> ATCC14579; Lane27: <i>B</i>. <i>thuringiensis</i> CTCC22945; Lane28: <i>Bacillus subtilis</i> ATCC9372; Lane29: ddH2O; Lane15 and Lane30: DNA marker. The predicted size of the product was approximately 430bp. A total of twenty–four <i>B</i>. <i>cereus</i> strains were confirmed by the PCR, and non-<i>B</i>. <i>cereus</i> strains did not yield a PCR product.</p