33 research outputs found
16S rRNA gene expression in different <i>Lactobacillus</i> species among condom, IUD and rhythm groups.
<p>Note: Error bars represent the mean ± SE of 16S rRNA gene expression in different <i>Lactobacillus</i> species. Variables were log transformed.</p
Demographic information and clinical data of subjects grouped into different non-hormonal contraception methods (N = 164).
<p>The data are shown as mean ± SE for age and n (%) for categorical variables.</p><p>P-values were obtained from ANOVA for comparison of age and Chi-square test for categorical variables among three groups.</p
Table_1_Sodium intake and the risk of heart failure and hypertension: epidemiological and Mendelian randomization analysis.docx
BackgroundThis study aimed to analysis the relationship between sodium intake and the risk of heart failure and hypertension through epidemiological studies and Mendelian randomization analysis.Methods and resultWe initially conducted an analysis using data from the National Health and Nutrition Examination Survey (NHANES) database to examine the relationship between sodium intake and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. After adjusting for confounding factors, we found a non-linear association between sodium intake and heart failure (p nonlinear = 0.0448). Subsequently, we utilized Mendelian randomization (MR) analysis by utilizing urinary sodium as a proxy for sodium intake to investigate the relationships between sodium and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. The results indicated that with increasing urinary sodium, there is an increase in systolic and diastolic blood pressure, as well as an elevated risk of heart failure and hypertension.ConclusionThe evidence provided by this study suggests that higher sodium intake is associated with an increased risk of heart failure and hypertension. However, excessively low sodium intake may not necessarily be beneficial, as there may be maximum benefits at a sodium intake level of around 3,000 mg/d.</p
Prevalence rate of H<sub>2</sub>O<sub>2</sub>-producing <i>Lactobacillus</i> among condom, IUD and rhythm groups.
<p>Note: LB, <i>Lactobacillus</i>; LB<sup>+</sup>, H<sub>2</sub>O<sub>2</sub>-producing <i>Lactobacillus</i>; LB<sup>-</sup>, non-H<sub>2</sub>O<sub>2</sub>-producing <i>Lactobacillus. P</i>-values were obtained from Chi-square test for comparison of LB<sup>+</sup> and LB among different groups, including 107/130 in the condom group, 60/88 in the IUD group and 51/75 in the rhythm group. Bonferroni correction was used for pairwise comparison (α = 0.017).</p
Table_2_Sodium intake and the risk of heart failure and hypertension: epidemiological and Mendelian randomization analysis.docx
BackgroundThis study aimed to analysis the relationship between sodium intake and the risk of heart failure and hypertension through epidemiological studies and Mendelian randomization analysis.Methods and resultWe initially conducted an analysis using data from the National Health and Nutrition Examination Survey (NHANES) database to examine the relationship between sodium intake and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. After adjusting for confounding factors, we found a non-linear association between sodium intake and heart failure (p nonlinear = 0.0448). Subsequently, we utilized Mendelian randomization (MR) analysis by utilizing urinary sodium as a proxy for sodium intake to investigate the relationships between sodium and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. The results indicated that with increasing urinary sodium, there is an increase in systolic and diastolic blood pressure, as well as an elevated risk of heart failure and hypertension.ConclusionThe evidence provided by this study suggests that higher sodium intake is associated with an increased risk of heart failure and hypertension. However, excessively low sodium intake may not necessarily be beneficial, as there may be maximum benefits at a sodium intake level of around 3,000 mg/d.</p
Primer sequences and reaction conditions used for PCR of <i>Lactobacillus</i>-specific 16S rRNA gene.
<p>Primer sequences and reaction conditions used for PCR of <i>Lactobacillus</i>-specific 16S rRNA gene.</p
Image_1_Sodium intake and the risk of heart failure and hypertension: epidemiological and Mendelian randomization analysis.TIFF
BackgroundThis study aimed to analysis the relationship between sodium intake and the risk of heart failure and hypertension through epidemiological studies and Mendelian randomization analysis.Methods and resultWe initially conducted an analysis using data from the National Health and Nutrition Examination Survey (NHANES) database to examine the relationship between sodium intake and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. After adjusting for confounding factors, we found a non-linear association between sodium intake and heart failure (p nonlinear = 0.0448). Subsequently, we utilized Mendelian randomization (MR) analysis by utilizing urinary sodium as a proxy for sodium intake to investigate the relationships between sodium and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. The results indicated that with increasing urinary sodium, there is an increase in systolic and diastolic blood pressure, as well as an elevated risk of heart failure and hypertension.ConclusionThe evidence provided by this study suggests that higher sodium intake is associated with an increased risk of heart failure and hypertension. However, excessively low sodium intake may not necessarily be beneficial, as there may be maximum benefits at a sodium intake level of around 3,000 mg/d.</p
Image_3_Sodium intake and the risk of heart failure and hypertension: epidemiological and Mendelian randomization analysis.TIFF
BackgroundThis study aimed to analysis the relationship between sodium intake and the risk of heart failure and hypertension through epidemiological studies and Mendelian randomization analysis.Methods and resultWe initially conducted an analysis using data from the National Health and Nutrition Examination Survey (NHANES) database to examine the relationship between sodium intake and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. After adjusting for confounding factors, we found a non-linear association between sodium intake and heart failure (p nonlinear = 0.0448). Subsequently, we utilized Mendelian randomization (MR) analysis by utilizing urinary sodium as a proxy for sodium intake to investigate the relationships between sodium and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. The results indicated that with increasing urinary sodium, there is an increase in systolic and diastolic blood pressure, as well as an elevated risk of heart failure and hypertension.ConclusionThe evidence provided by this study suggests that higher sodium intake is associated with an increased risk of heart failure and hypertension. However, excessively low sodium intake may not necessarily be beneficial, as there may be maximum benefits at a sodium intake level of around 3,000 mg/d.</p
Prevalence and quantification of <i>Lactobacillus</i> in women grouped by non-hormonal contraception methods.
<p>LB, <i>Lactobacillus</i>; LB<sup>+</sup>, H<sub>2</sub>O<sub>2</sub>-producing <i>Lactobacillus</i>; LB<sup>-</sup>, non-H<sub>2</sub>O<sub>2</sub>-producing <i>Lactobacillus.</i> Data are shown as mean ± SE for colony count (log<sub>10</sub>CFU/ml), gene expression (log<sub>10</sub>copies/ml) and n(%) for prevalence of women with LB.</p>∧<p>Adjusted for age. <sup>#</sup>Bonferroni correction was used for pairwise comparison (α = 0.017).</p>*<p>Log transformed prior to statistical test. Bold and italic = Significant at the Bonferroni level; italic = Significant but not at the Bonferroni level.</p
Image_2_Sodium intake and the risk of heart failure and hypertension: epidemiological and Mendelian randomization analysis.TIFF
BackgroundThis study aimed to analysis the relationship between sodium intake and the risk of heart failure and hypertension through epidemiological studies and Mendelian randomization analysis.Methods and resultWe initially conducted an analysis using data from the National Health and Nutrition Examination Survey (NHANES) database to examine the relationship between sodium intake and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. After adjusting for confounding factors, we found a non-linear association between sodium intake and heart failure (p nonlinear = 0.0448). Subsequently, we utilized Mendelian randomization (MR) analysis by utilizing urinary sodium as a proxy for sodium intake to investigate the relationships between sodium and heart failure, hypertension, systolic blood pressure, and diastolic blood pressure. The results indicated that with increasing urinary sodium, there is an increase in systolic and diastolic blood pressure, as well as an elevated risk of heart failure and hypertension.ConclusionThe evidence provided by this study suggests that higher sodium intake is associated with an increased risk of heart failure and hypertension. However, excessively low sodium intake may not necessarily be beneficial, as there may be maximum benefits at a sodium intake level of around 3,000 mg/d.</p