Sequential Vapor Infiltration Treatment Enhances the Ionic Current Rectification Performance of Composite Membranes Based on Mesoporous Silica Confined in Anodic Alumina

Ionic current rectification of nanofluidic diode membranes has been studied widely in recent years because it is analogous to the functionality of biological ion channels in principle. We report a new method to fabricate ionic current rectification membranes based on mesoporous silica confined in anodic aluminum oxide (AAO) membranes. Two types of mesostructured silica nanocomposites, hexagonal structure and nanoparticle stacked structure, were used to asymmetrically fill nanochannels of AAO membranes by a vapor-phase synthesis (VPS) method with aspiration approach and were further modified via sequence vapor infiltration (SVI) treatment. The ionic current measurements indicated that SVI treatment can modulate the asymmetric ionic transport in prepared membranes, which exhibited clear ionic current rectification phenomenon under optimal conditions. The ionic current rectifying behavior is derived from the asymmetry of surface conformations, silica species components, and hydrophobic wettability, which are created by the asymmetrical filling type, silica depositions on the heterogeneous membranes, and the condensation of silanol groups. This article provides a considerable strategy to fabricate composite membranes with obvious ionic current rectification performance via the cooperation of the VPS method and SVI treatment and opens up the potential of mesoporous silica confined in AAO membranes to mimic fluid transport in biological processes

Donut-Shaped Nanoparticles Templated by Cyclic Bottlebrush Polymers

Cyclic bottlebrush polymers were synthesized and used as single molecular templates to prepare donut-shaped hybrid nanoparticles with organo-silica cross-linked and gold nanocluster coordinated internal structures. “Grafting-onto” strategy was adopted to prepare cyclic bottlebrush polymers by combining ring-expansion metathesis polymerization (REMP), reversible addition–fragmentation chain transfer (RAFT) polymerization, and triazolinedione (TAD)-diene click reaction. In this approach, cyclic poly­(norbornene imide) backbones with diene side groups (C-PNB-diene) were synthesized based on REMP technique. TAD-terminated diblock copolymer side chains were produced from RAFT polymerization including TAD-terminated poly­(3-(triethoxysilyl)­propyl methacrylate)-<i>block</i>-poly­(oligo­(ethylene glycol) methacrylate) (TAD-PTEPM-<i>b</i>-POEGMA) and TAD-terminated poly­(glycidyl methacrylate)-<i>block</i>-poly­(oligo­(ethylene glycol) methacrylate) (TAD-PGMA-<i>b</i>-POEGMA). The cyclic bottlebrush polymers <b>1</b> and <b>2</b> were then prepared by virtue of TAD-diene click reaction to graft TAD-PTEPM-<i>b</i>-POEGMA and TAD-PGMA-<i>b</i>-POEGMA side chains onto C-PNB-diene backbones, respectively. Furthermore, the donut-shaped hybrid nanoparticles with organo-silica cross-linked internal structures were obtained by in situ cross-linking PTEPM domains of the cyclic bottlebrush polymer <b>1</b> templates. For the formation of donut-shaped hybrid nanoparticles coordinating gold nanoclusters inside, the cyclic bottlebrush polymer <b>2</b> templates were first postmodified to introduce the functional pyridine groups inside the PGMA domains, which were then used as location to coordinate the gold nanoclusters

One-Step Synthesis of Uniform Double-Shelled Polystyrene/Poly(<i>o</i>‑toluidine) Composite Hollow Spheres

Uniform double-shelled polystyrene/poly­(<i>o</i>-toluidine) (PS/POT) composite hollow spheres with tunable shell thickness of the POT layer have been successfully synthesized by a simple method. POT was directly coated onto the surface of negatively charged PS template spheres, which were synthesized by soap-free emulsion polymerization. Surprisingly, the resultant spheres show a double-shelled hollow structure with PS as an inner wall and POT as an exterior shell. In comparison to conventional methods, the benefits of this route are that neither organic solvents nor high-temperature calcinations were used to remove the PS template. The surface morphology, the shell thickness, and the compositions of the double-shelled spheres were systematically characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier transform infrared (FTIR) spectroscopy. On the basis of our interpretation of experimental results, a mechanism for the formation of the double-shelled PS/POT composite hollow spheres is proposed

L'Auto-vélo : automobilisme, cyclisme, athlétisme, yachting, aérostation, escrime, hippisme / dir. Henri Desgranges

09 octobre 19241924/10/09 (A25,N8699)

Additional file 3: of Sexual dysfunction and mode of delivery in Chinese primiparous women: a systematic review and meta-analysis

The results of the included studies through sensitivity analysis. Figure S1. Sensitivity analysis of 5 studies with the random effects model for sexual satisfaction within 3 months after delivery. Figure S2. Sensitivity analysis of 6 studies with the fixed effects model for sexual satisfaction within 6 months after delivery. Figure S3. Sensitivity analysis of 9 studies with the random effects model for resumed intercourse within 3 months after delivery. Figure S4. Sensitivity analysis of 8 studies with the fixed effects model for resumed intercourse within 6 months after delivery. Figure S5. Sensitivity analysis of 7 studies with the fixed effects model for sexual pain within 3 months after delivery. Figure S6. Sensitivity analysis of 7 studies with the fixed effects model for sexual pain within 6 months after delivery. (DOCX 957 kb

Additional file 1: of Mesenchymal stem cells in the treatment of Cesarean section skin scars: study protocol for a randomized, controlled trial

SPIRIT checklist. (DOCX 43 kb

Characteristic of included studies in meta-analysis.

<p>Characteristic of included studies in meta-analysis.</p

The Incidence of Postpartum Hemorrhage in Pregnant Women with Placenta Previa: A Systematic Review and Meta-Analysis

<div><p>Background</p><p>The global burden of postpartum hemorrhage (PPH) in women with placenta previa is a major public health concern. Although there are different reports on the incidence of PPH in different countries, to date, no research has reviewed them.</p><p>Objective</p><p>The aim of this study was to calculate the average point incidence of PPH in women with placenta previa.</p><p>Methods</p><p>A systematic review and meta-analysis of observational studies estimating PPH in women with placenta previa was conducted through literature searches in four databases in Jul 2016. This study was totally conducted according to the MOOSE guidelines and in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses standard.</p><p>Results</p><p>From 1148 obtained studies, 11 included in the meta-analysis, which involved 5146 unique pregnant women with placenta previa. The overall pooled incidence of PPH was 22.3% (95% CI 15.8–28.7%). In the subgroup, the prevalence was 27.4% in placenta previas, and was 14.5% in low-lying placenta previa; the highest prevalence was estimated in Northern America (26.3%, 95%CI 11.0–41.6%), followed by the Asia (20.7%, 95%CI 12.8–28.6%), Australia (19.2%, 95% CI 17.2–21.1%) and Europe (17.8%, 95% CI, 11.5%-24.0%).</p><p>Conclusions</p><p>The summary estimate of the incidence of PPH among women with placenta previa was considerable in this systematic review. The results will be crucial in prevention, treatment, and identification of PPH among pregnant women with placenta previa and will be contributed to the planning and implantation of relevant public health strategies.</p></div

Results of meta-regression for the incidence of postpartum hemorrhage.

<p>Results of meta-regression for the incidence of postpartum hemorrhage.</p

Funnel plot by subgroup analysis of world regions.

<p>Funnel plot by subgroup analysis of world regions.</p