Synthesis, Solid-State Structures, and Molecular Recognition of Chiral Molecular Tweezer and Related Structures Based on a Rigid Bis-Naphthalene Cleft

The rigid and nonchiral bis-naphthalene cleft was used for the first time as a scaffold to build a chiral molecular tweezer. The molecular tweezer and its related compounds have been synthesized and carefully characterized by X-ray crystallography and NMR spectroscopy. Their solid-state structures and molecular recognition properties have also been studied

Regioselective Synthesis of Methylene-Bridged Naphthalene Oligomers and Their Host–Guest Chemistry

In this research, we report the regioselective synthesis of methylene-bridged naphthalene oligomers from 2,6-dialkoxyl naphthanene and paraformaldehyde by using <i>p</i>-TsOH as the catalyst and CH₂Cl₂ as the solvent. The structures were characterized by NMR spectroscopy and X-ray crystallography. Their host–guest chemistry with organic cations was studied, and optimal naphthalene numbers in the oligomers were revealed for different guests. In addition, the reason for the unsuccessful synthesis of methylene-bridged naphthalene macrocycles was discussed