53 research outputs found

    The language of religious affiliation: social, emotional, and cognitive differences

    Get PDF
    Religious affiliation is an important identifying characteristic for many individuals and relates to numerous life outcomes including health, well-being, policy positions, and cognitive style. Using methods from computational linguistics, we examined language from 12,815 Facebook users in the United States and United Kingdom who indicated their religious affiliation. Religious individuals used more positive emotion words (β = .278, p < .0001) and social themes such as family (β = .242, p < .0001), while nonreligious people expressed more negative emotions like anger (β = −.427, p < .0001) and categories related to cognitive processes, like tentativeness (β = −.153, p < .0001). Nonreligious individuals also used more themes related to the body (β = −.265, p < .0001) and death (β = −.247, p < .0001). The findings offer directions for future research on religious affiliation, specifically in terms of social, emotional, and cognitive differences

    PDCD4 protein expression in miR-21 inhibitor–transfected cells after IL-6 treatment.

    No full text
    <p>PDCD4 protein expression was significantly higher in prostate cancer cells transfected with the miR-21-inhibitor before Il-6 treatment than in cells not transfected with the inhibitor (one-way ANOVA test: <i>F</i> value = 241.781, <i>P</i> < 0.05). Levels of PDCD4 protein expression in transfected and nontransfected cells of both cell lines were significantly different (LSD test: <i>P</i> < 0.05).</p

    Effect of mir-21 inhibitor transfection on PDCD4 mRNA and protein expression in PC-3 and LNCaP cells.

    No full text
    <p>qRT-PCR results showing an increase in PDCD4 mRNA expression of PC-3 and LNCaP cells transfected with miR-21 inhibitor, indicating that PDCD4 mRNA was differentially expressed between the two groups. Among the miR-21–inhibited cells, PDCD4 mRNA expression in LNCaP cells was significantly higher than that in PC-3 cells. PDCD4 mRNA expression of LNCaP and PC-3 cells was downregulated after a 24-h treatment with different concentrations of IL-6. <b>(b)</b> Western blot analysis showing an increase in levels of expression of the PDCD4 protein in PC-3 and LNCaP cells transfected with the miR-21 inhibitor. Nontransfected and negative-control cells were ranked 1 through 6 in the rank test of paired samples. Levels of PDCD4 protein expression of LNCaP and PC-3 cells was downregulated after a 24-h treatment with different concentrations of IL-6.</p

    PDCD4 expression after IL-6 treatment.

    No full text
    <p>Levels of PDCD4 mRNA expression in LNCaP and PC-3 cells were downregulated after a 24-h treatment with IL-6 at 0, 5, or 10 ng/mL. The difference there was statistical significance (<b>a</b>) between each other. The same difference was also observed in the levels of PDCD4 protein expression (<b>b</b>). <b>(a)</b> PDCD4 mRNA expression of LNCaP and PC-3 cells was downregulated after a 24-h treatment with IL-6 at 10 ng/mL. <b>(b)</b> PDCD4 protein expression of LNCaP and PC-3 cells was downregulated after a 24-h treatment with IL-6 at 10 ng/mL,</p

    PDCD4 and PSA expression in prostate cancer, prostatic intraepithelial neoplasia and prostatic hyperplasia.

    No full text
    <p>In prostate cancer, considerable amount of normal gland is lacking. Cancer nests are formed with irregular cribriform glands, and cancer infiltrates the muscle tissue and cell cytoplasm. This staining pattern was graded PDCD4(+), PSA(+++). In prostatic intraepithelial neoplasia, the staining pattern was graded PDCD4(++), PSA (++). In prostatic hyperplasia/glandular hyperplasia, the nuclear staining pattern was graded PDCD4 (+++), PSA (+/−). The expression of PDCD4 and PSA were different (<i>x</i><sup>2</sup> = 8.632, <i>P</i><0.05) among the 3 tissue types. In the Spearman rank test, the expression levels of PDCD4 and PSA among the 3 prostate tissue types were negatively correlated (−1 < <i>r</i> < 0).</p

    Additional file 1: Figure S1. of Molecular evolution of two asymptomatic echovirus 6 strains that constitute a novel branch of recently epidemic echovirus 6 in China

    No full text
    Polygenetic tree based on the VP1 sequences of EVs. The tree includes nearly all of the E6 strains found in China by 2016. The black circles indicate the strains that we found, and the black triangles indicate the closest strains to them. Figure S2. Similarity plot and bootscanning analysis queried by K843. (a) The similarity plot between K843 and other EVs. (b) The bootscanning analysis for K843. The analyses were conducted via Simplot v3.5.1 using a sliding window of 400 nucleotides moving in steps of 20 nucleotides. (PDF 919 kb

    PCA of the three scenarios.

    No full text
    <p>The principal component analyses (PCAs) of summary statistics were performed using DIYABC 2.0 software with three different scenarios (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134334#pone.0134334.s002" target="_blank">S2 Fig</a>). The summary statistics of the different scenarios were calculated based on the computer simulation of HLA-DRB1 sequences under widely predefined demographic parameters. The observed data represent summary statistics of real HLA-DRB1 sequence data.</p

    Information about the seven populations sampled for HLA-DRB1 genotyping.

    No full text
    <p>Lat and Long represent latitude (north) and longitude (east), respectively.</p><p>* 10 STR analyses were performed from 48 members of this population.</p><p>Information about the seven populations sampled for HLA-DRB1 genotyping.</p
    corecore