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Comment on "Length-dependent translation of messenger RNA by ribosomes"
In the recent paper of Valleriani {\it et al} [Phys. Rev. E {\bf 83}, 042903
(2011)], a simple model for describing the translation of messenger RNA (mRNA)
by ribosomes is presented, and an expression of the translational ratio ,
defined as the ratio of translation rate of protein from mRNA
to degradation rate of protein, is obtained. The key point to get
this ratio is to get the translation rate . In the study
of Valleriani {\it et al}, is assumed to be the mean value of
measured translation rate, i.e. the mean value of ratio of the translation
number of protein to the lifetime of mRNA. However, in experiments different
methods might be used to get . Therefore, for the sake of
future application of their model to more experimental data analysis, in this
comment three methods to get the translation rate , and
consequently the translational ratio , are provided. Based on one of the
methods which might be employed in most of the experiments, we find that the
translational ratio decays exponentially with the length of mRNA in
prokaryotic cells, and decays reciprocally with the length of mRNA in
eukaryotic cells. This result is slight different from that obtained in
Valleriani's study
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