2,581 research outputs found

    Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid

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    Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma. Methods: Study design: Case control study. Total homocysteine was quantified in CSF and plasma samples of CJD patients (n = 13) and healthy controls (n = 13). Results: Mean values in healthy controls: 0.15 mumol/l +/- 0.07 (CSF) and 9.10 mumol/l +/- 2.99 (plasma); mean values in CJD patients: 0.13 mumol/l +/- 0.03 (CSF) and 9.22 mumol/l +/- 1.81 (plasma). No significant differences between CJD patients and controls were observed (Mann-Whitney U, p > 0.05). Conclusions: The results indicate that the CSF and plasma of CJD patients showed no higher endogenous levels of homocysteine as compared to normal healthy controls. These findings provide no evidence for an additional role of homocysteine in the pathogenetic mechanisms underlying CJD neurodegeneration. Copyright (C) 2005 S. Karger AG, Basel

    The Domain-Generality and Durability of Efficient Learning

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    People differ in how quickly they learn information and how long they remember it, and a common finding in the literature is that a quicker rate of learning coincides with better retention for the learned material. Zerr and colleagues (2017) termed the relation between learning rate and retention as learning efficiency, with more efficient learning representing both a faster acquisition rate and better memory performance after a delay. Zerr et al. also demonstrated in separate experiments that how efficiently someone learns is stable across a range of days and years. The current thesis includes two experiments addressing additional questions regarding efficient learning. Experiment 1 (N = 119) examined whether efficient learning is generalizable across stimuli, including Lithuanian-English (verbal-verbal) and Chinese-English (visuospatial-verbal) paired associates. Experiment 2 (N = 190) assessed whether faster learners demonstrate better retention at a longer delay of 1 week, and also preliminarily examined whether faster and slower learners demonstrate differential rates of forgetting. These experiments demonstrated that learning efficiency is generalizable across stimuli and that faster learners maintain a retentive advantage at longer delays of 1 week

    Athletic Identity Association and Prospective Basic Psychological Needs Satisfaction Predict Attitudes of Collegiate Athletes Toward Seeking Help From the Athletic Department

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    There is an epidemic of mental health issues that has begun to be more openly talked about in college athletics. In 2022, the National Collegiate Athletic Association has found that college student-athletes are now 1.5-2 times more likely to report struggling with mental health than ever before. Previous research has shown a significant association with basic psychological needs satisfaction and overall psychological well-being. Furthermore, the purpose of this study was to investigate the possible ways that reported of autonomy, competence, and relatedness need satisfaction predicted whether athletes would seek mental health services and identify how athletic identity plays into this relationship. Participants in this study included 52 current National Collegiate Athletic Association collegiate student-athletes (34 female and 18 male) from Division I, Division II, and Division III schools. Results indicated a significant relationship between the three factors of basic psychological needs satisfaction (competence, autonomy, and relatedness) and attitudes toward seeking professional psychological help, as well as a significant result between autonomy and relatedness association with athletic identity. No significance was found between athletic identity and predictions of attitudes toward seeking professional psychological help

    Chatting as Brainstorming: Drafting Research Questions with Generative AI in an Introductory Composition Course

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    Many people are interested in generative AI tools such as ChatGPT as potential assistants. For this assignment, students in an introductory composition course will use ChatGPT (or a similar generative AI tool) as a brainstorming assistant to develop a research question for a specific project. Through a guided reflective process, students will 1) produce a well-formed, productive research question and a related set of keywords to guide their database research and 2) consider how generative AI tools such as Chat-GPT might be used productively and ethically as drafting assistants

    Partial dynamical systems and AF C*-algebras

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    By utilizing the connections between C*-algebras, groupoids, and inverse semigroups, we obtain a characterization theorem, in terms of dynamical systems, of approximately finite-dimensional (AF) C*-algebras. The dynamical systems considered in this characterization consist of partially defined homeomorphisms, and our theorem is applied to obtain a result about crossed product C*-algebras. The ideas developed here are then used to compute the K-theory for AF algebras, and these K-theoretic calculations are applied to some specific examples of AF algebras. Finally, we show that for a given dimension group, a groupoid can be obtained directly from the dimension group\u27s structure whose associated C*-algebra has K0 group isomorphic to the original dimension group

    Equivalence relation groupoids associated with certain linearly ordered dimension groups

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    AbstractWe consider linearly ordered, Archimedean dimension groups (G,G+,u) for which the group G/〈u〉 is torsion-free. It will be shown that if, in addition, G/〈u〉 is generated by a single element (i.e., G/〈u〉≅Z), then (G,G+,u) is isomorphic to (Z+τZ,(Z+τZ)∩R+,1) for some irrational number τ∈(0,1). This amounts to an extension of related results where dimension groups for which G/〈u〉 is torsion were considered. We will prove, in the case of the Fibonacci dimension group, that these results can be used to directly construct an equivalence relation groupoid whose C∗-algebra is the Fibonacci C∗-algebra

    Finding a deeper understanding of the intersection among trauma, social-emotional learning, and dropping out: a phenomenological study

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    Doctor of EducationDepartment of Educational LeadershipAlex Red CornRobert HachiyaThe purpose of this phenomenological interview study was to examine the lived experiences of five childhood trauma survivors who dropped out of high school in central Kansas within the past three years but eventually decided to pursue their diploma in an adult learning center. With the state of Kansas implementing the Kansans CAN (2015) initiative, which emphasizes social-emotional learning and high school graduation, this qualitative study explores the intersection of trauma, social-emotional learning, and dropping out. Using purposeful sampling and in-depth interviews, the participants shared their lived experiences at home, in school, and the community as it relates to their ultimate decision to discontinue their schooling. The results of this study deepen our understanding of how trauma and social-emotional learning played significant roles in the participants’ decisions to leave school. However, specifically they revealed how deep relationships and emotional connections factored into their decisions to pursue a high school diploma. This study elevates conversations about the need to articulate the strengths and differences found in the implementation of social-emotional curricula and trauma-informed teaching in schools. Additionally, the participants’ stories support the need for more profound levels of emotional connectedness with traumatized students in schools and raise questions about how much teachers are prepared for or feel comfortable with – building those kinds of relationships with their students

    Towards the automation of sand dune detection in the bathymetry

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    International audienceIntroduction The advances in echo sounder (MultiBeam EchoSounder) and positioning (GPS) technologies of the past two decades enabled us to survey larger areas, faster and more accurately. The collected data show how diverse underwater sand dunes are in terms of shape, spatial organization, dimensions, dynamics, etc. To deal with this large amount of bathymetric data, manual processing appears outdated. By consequent, tools allowing to quantitatively describe their morphology and dynamics have been developed [1,2,3]. It mainly enables to objectively characterize the sand dunes and banks. Unlike the existing tools, we aim at describing each dune independently with a set of morphometric parameters. With this goal of dune characterization, the first step consists in detecting the dunes in the bathymetry. As a preliminary approach, we propose a detection technique inspired from geomorphometry
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