Trends in Student Radicalization across University Campuses in Afghanistan

This study aims to examine the trends in student radicalization across eight university campuses in Afghanistan. We conclude from our survey of student and staff views and an analysis of the character of protests across campuses that the extent of student radicalization varies. In particular, we come to three noteworthy findings. First, most university students are more concerned over prospects of post-graduation follow-on careers than ideological ambition. Second, while we find that most students and lecturers denounce radical views and violence, a relatively more aggressive response to both the policies of the Afghan government and the armed international intervention exhibited by students from universities in Kabul, Qandahar and Nangarhar suggests differentiated patterns across university campuses, with these campuses suggestive of a stronger tendency toward radicalized views. Finally, as an institution, the university does not play a strong role in the radicalization of its students. Rather, a charged political climate and the readily available opportunity to mobilize quickly enable students to stand in protest rather easily. However, findings also suggest that it is this same easy access to mobilize in protest that seems to attract a number of external groups as evident by the black, white and green flags representative of al-Qaeda, the Taliban, and the militant wing of Hezb-e- Islami Hekmatyar. Moreover, it is these protests that seem to encourage polarization and consequential division on campus which increasingly resemble the practice of takfir. Referring to the practice of excommunication wherein one Muslim declares that another Muslim has abandoned Islam, takfir is in direct competition with the more tolerant teachings common to the characteristically liberal curriculum of public universities. While protest in and of itself is a characteristic common to progressive democracies, evidence suggests that some student protests do call for division along sectarian lines or the suppression of women’s rights, both of which stand in contradiction to democratic principles and pose a threat to stability. With more than sixty-three percent of the Afghan population under the age of twenty-four, left unchecked such influence has the likelihood and potential to expand with substantial consequences for development and security in Afghanistan. As Afghanistan moves into a new phase of its era of state-building, a special focus on meeting the needs of its youth and in particular of Afghan university students is indispensable in meeting and maintaining lasting stability and prosperity. This study is the first part of an ongoing series of papers dedicated to examining the trends in radicalization across the various sectors throughout Afghanistan. Launched in late 2013, we plan follow-on studies to complement the series, including examinations of the trends in radicalization in madrassas across Afghanistan and within the Afghan security forces

Trends of Radicalization among the Ranks of the Afghan National Police

This study examines and compares trends of radicalization among the ranks of Afghan National Police (ANP) force across eleven provinces in Afghanistan. This is the first part of an ongoing series of papers dedicated to examining the evolving trends in radicalization among the Afghan National Defense and Security Force (ANDSF). Since the formation of the defense and security in 2002, various potential manifestations of radicalization, including insider attacks, dereliction of duty, and desertion have plagued its ranks. Radicalization is broadly defined as constraints on both the perspective of individuals and their tolerance to ideology and practices which diverge and differentiate from their own political, religious and social beliefs. Making the distinction between political deviance (PD), religious extremism (RE), and social intolerance (SI), 1498 uniformed rank and file personnel, 151 commissioned officers, and 8 uniformed religious leaders from among the ANP were surveyed on their views toward the political system in Afghanistan, anti-government elements including the Taliban, democracy in light of Islamic values, and women and human rights

Models of education in medicine, public health, and engineering

Discussion on global health in both the academic and the public domain has focused largely on research, capacity building, and service delivery. Although these efforts along with financial commitments from public and private partners have contributed to a broader appreciation and understanding of global health challenges, the reflection of global health in academic training has largely been lacking. However, integrative models are beginning to appear

A Method Impact Assessment Framework for User Experience Evaluations with Children

Based upon a review of the literature, this paper presents a Method Impact Assessment Framework. Theoretically synthesized, the framework offers five dimensions: (1) the role of the child, (2) the user experience construct, (3) system, (4) epistemological perspective, (5) Practical and Ethical Concerns. Although other dimensions could have been construed, these were judged to be the most pertinent to understanding evaluation methods with children. The framework thus provides a critical lens in which evaluation methods can be assessed by the Children Computer Interaction (CCI) Community to inform method selection

The effect of intrapartum antibiotics on early-onset neonatal sepsis in Dhaka, Bangladesh: a propensity score matched analysis

Background: We estimate the effect of antibiotics given in the intrapartum period on early-onset neonatal sepsis in Dhaka, Bangladesh using propensity score techniques. Methods: We followed 600 mother-newborn pairs as part of a cohort study at a maternity center in Dhaka. Some pregnant women received one dose of intravenous antibiotics during labor based on clinician discretion. Newborns were followed over the first seven days of life for early-onset neonatal sepsis defined by a modified version of the World Health Organization Young Infants Integrated Management of Childhood Illnesses criteria. Using propensity scores we matched women who received antibiotics with similar women who did not. A final logistic regression model predicting sepsis was run in the matched sample controlling for additional potential confounders. Results: Of the 600 mother-newborn pairs, 48 mothers (8.0%) received antibiotics during the intrapartum period. Seventy-seven newborns (12.8%) were classified with early-onset neonatal sepsis. Antibiotics appeared to be protective (odds ratio 0.381, 95% confidence interval 0.115–1.258), however this was not statistically significant. The results were similar after adjusting for prematurity, wealth status, and maternal colonization status (odds ratio 0.361, 95% confidence interval 0.106–1.225). Conclusions: Antibiotics administered during the intrapartum period may reduce the risk of early-onset neonatal sepsis in high neonatal mortality settings like Dhaka

Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases.

Iron accumulates in the ageing brain and in brains with neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and Down syndrome (DS) dementia. However, the mechanisms of iron deposition and regional selectivity in the brain are ill-understood. The identification of several proteins that are involved in iron homeostasis, transport, and regulation suggests avenues to explore their function in neurodegenerative diseases. To uncover the molecular mechanisms underlying this association, we investigated the distribution and expression of these key iron proteins in brain tissues of patients with AD, DS, PD, and compared them with age-matched controls. Ferritin is an iron storage protein that is deposited in senile plaques in the AD and DS brain, as well as in neuromelanin-containing neurons in the Lewy bodies in PD brain. The transporter of ferrous iron, Divalent metal protein 1 (DMT1), was observed solely in the capillary endothelium and in astrocytes close to the ventricles with unchanged expression in PD. The principal iron transporter, ferroportin, is strikingly reduced in the AD brain compared to age-matched controls. Extensive blood vessel damage in the basal ganglia and deposition of punctate ferritin heavy chain (FTH) and hepcidin were found in the caudate and putamen within striosomes/matrix in both PD and DS brains. We suggest that downregulation of ferroportin could be a key reason for iron mismanagement through disruption of cellular entry and exit pathways of the endothelium. Membrane damage and subsequent impairment of ferroportin and hepcidin causes oxidative stress that contributes to neurodegeneration seen in DS, AD, and in PD subjects. We further propose that a lack of ferritin contributes to neurodegeneration as a consequence of failure to export toxic metals from the cortex in AD/DS and from the substantia nigra and caudate/putamen in PD brain

TREM2, Tau and ApoE in choroid plexus in AD pathology

Background: Genetic factors that influence AD risk include mutations in TREM2 and allelic variants of Apolipoprotein-E, influencing AD pathology in the general population and in Down syndrome (DS). Evidence shows that dysfunction of the choroid plexus (CP) may compromise the blood-CSF barrier, altering secretary, transport and immune function that can affect AD pathology Objective: To investigate the genotype and phenotype of DS individuals in relation to choroid plexus damage and blood-CSF barrier leakage to identify markers that could facilitate early diagnosis of AD in DS. Methods: To assess allele frequency and haplotype associations ApoE, Tau, TREM2 and HLADR were analysed by SNP analysis in DS participants (n=47) and controls (n = 50). The corresponding plasma protein levels were measured by ELISA. Post-mortem brains from DS, AD and age matched controls were analysed by immunohistochemistry. Results: Haplotype analysis showed that individuals with Tau H1/H1 and ApoE 4 genotypes were more prevalent among DS participants with an earlier diagnosis of dementia (17%) compared to H1/H2 haplotypes (6%). Plasma TREM2 levels decreased whereas phospho-Tau levels increased with age in DS. In AD and DS brain insoluble Tau and ApoE were found to accumulate in the choroid plexus. Conclusion: Accumulation of Tau and ApoE in the choroid plexus may increase the oligomerisation rate of Aβ42 and impair Tau trafficking, leading to AD pathology. We have identified a high-risk haplotype: ApoE 4, Tau/ H1 and TREM2/T, that manifests age-related changes potentially opening a window for treatment many years prior to the manifestation of the AD dementia