Forest plot showing the association between <i>PDE4B</i> SNPs and schizophrenia under recessive model.

<p>Forest plot showing the association between <i>PDE4B</i> SNPs and schizophrenia under recessive model.</p

Forest plot showing the association between <i>PDE4B</i> SNPs and schizophrenia under allelic model.

<p>Forest plot showing the association between <i>PDE4B</i> SNPs and schizophrenia under allelic model.</p

Forest plot showing the association between <i>PDE4B</i> SNPs and schizophrenia under dominant model.

<p>Forest plot showing the association between <i>PDE4B</i> SNPs and schizophrenia under dominant model.</p

PRISMA flow diagram showing study selection process.

<p>PRISMA flow diagram showing study selection process.</p

Mechanical Modulation of Flexible Schiff Base Derivatives with Fluorescence Properties Based on Crystal Engineering

The application of organic molecular crystals is currently limited by their poor mechanical properties. Crystal engineering could be an effective approach to design and modify organic crystals with different structures and diverse mechanical and other properties. In this work, we synthesized a series of N-salicylideneaniline derivatives (Schiff Bases) with different substituents, which exhibited various mechano-responsive behaviors like two-dimensional (2D) elasticity, plasticity, twisting, and fracture. Besides that, distinct fluorescence emission behaviors were observed due to their different crystal structures. Mechanofluorochromic phenomena were demonstrated in flexible crystals where a reversible fluorescence peak shift occurred in elastic crystals and a red shift appeared in plastic crystals. Organic crystals with mechano-sensitive behaviors and fluorescence properties hold great potential in flexible optoelectronic materials, such as sensors and actuators

Exploration of the Solid Forms of Cepharanthine: Crystal Structure and Phase Transformation

Recently, researchers found the abilities of cepharanthine (CEP) to prevent and treat coronavirus. However, the study about CEP solid forms has been rarely reported. In this study, the crystal structure of CEP form I was first solved, and eight solvates were screened and discovered based on the conductor-like screening model for real solvents. The crystal structures of five solvates of CEP with methanol (SMeOH), acetonitrile (SACN), methyl acetate (SMA), ethyl acetate (SEA), and butyl acetate (SBA) were solved. The results showed that five solvates belonged to isolated-site solvates. Hydrogen bonding between the solvent molecule and the active pharmaceutical ingredient molecule was present only in SMeOH. The remaining four solvates formed C–H···O weak hydrogen bonds and C–H···π interactions between the host and guest. The mechanism of solvate formation was explained by calculating the packing coefficients, and it was proved that the introduction of solvent molecules mainly made the crystal structure packed more effectively. In addition, the desolvation of the five solvates were studied and found that the desolvation of SMeOH followed a cooperative mechanism, while SACN, SMA, SEA, and SBA conformed to a destruction-collapse mechanism

Mechanical Modulation of Flexible Schiff Base Derivatives with Fluorescence Properties Based on Crystal Engineering

The application of organic molecular crystals is currently limited by their poor mechanical properties. Crystal engineering could be an effective approach to design and modify organic crystals with different structures and diverse mechanical and other properties. In this work, we synthesized a series of N-salicylideneaniline derivatives (Schiff Bases) with different substituents, which exhibited various mechano-responsive behaviors like two-dimensional (2D) elasticity, plasticity, twisting, and fracture. Besides that, distinct fluorescence emission behaviors were observed due to their different crystal structures. Mechanofluorochromic phenomena were demonstrated in flexible crystals where a reversible fluorescence peak shift occurred in elastic crystals and a red shift appeared in plastic crystals. Organic crystals with mechano-sensitive behaviors and fluorescence properties hold great potential in flexible optoelectronic materials, such as sensors and actuators

Mechanical Modulation of Flexible Schiff Base Derivatives with Fluorescence Properties Based on Crystal Engineering

The application of organic molecular crystals is currently limited by their poor mechanical properties. Crystal engineering could be an effective approach to design and modify organic crystals with different structures and diverse mechanical and other properties. In this work, we synthesized a series of N-salicylideneaniline derivatives (Schiff Bases) with different substituents, which exhibited various mechano-responsive behaviors like two-dimensional (2D) elasticity, plasticity, twisting, and fracture. Besides that, distinct fluorescence emission behaviors were observed due to their different crystal structures. Mechanofluorochromic phenomena were demonstrated in flexible crystals where a reversible fluorescence peak shift occurred in elastic crystals and a red shift appeared in plastic crystals. Organic crystals with mechano-sensitive behaviors and fluorescence properties hold great potential in flexible optoelectronic materials, such as sensors and actuators

Mechanical Modulation of Flexible Schiff Base Derivatives with Fluorescence Properties Based on Crystal Engineering

The application of organic molecular crystals is currently limited by their poor mechanical properties. Crystal engineering could be an effective approach to design and modify organic crystals with different structures and diverse mechanical and other properties. In this work, we synthesized a series of N-salicylideneaniline derivatives (Schiff Bases) with different substituents, which exhibited various mechano-responsive behaviors like two-dimensional (2D) elasticity, plasticity, twisting, and fracture. Besides that, distinct fluorescence emission behaviors were observed due to their different crystal structures. Mechanofluorochromic phenomena were demonstrated in flexible crystals where a reversible fluorescence peak shift occurred in elastic crystals and a red shift appeared in plastic crystals. Organic crystals with mechano-sensitive behaviors and fluorescence properties hold great potential in flexible optoelectronic materials, such as sensors and actuators