6 research outputs found
Additional file 1 of Association between white blood cell count to hemoglobin ratio and risk of in-hospital mortality in patients with lung cancer
Additional file 1: Supplementary Table 1. Sensitivity analysis before and after interpolatio
FeCl<sub>3</sub>·6H<sub>2</sub>O‑Catalyzed Intramolecular Allylic Amination: Synthesis of Substituted Dihydroquinolines and Quinolines
A facile and efficient method to synthesize 2- or 4-substituted
1,2-dihydroquinolines and quinolines catalyzed by FeCl<sub>3</sub>·6H<sub>2</sub>O (2 mol %) was described. The iron-catalyzed
intramolecular allylic amination of 2-aminophenyl-1-en-3-ols proceeded
smoothly to afford 13 1,2-dihydroquinoline and 8 quinoline derivatives
under mild reaction conditions with good to excellent yields (up to
96%)
Construction of Topological Macromolecular Side Chains Packing Model: Study Unique Relationship and Differences in LC-Microstructures and Properties of Two Analogous Architectures with Well-Designed Side Attachment Density
A new series of linear–comb
and 4-arm star–comb side
chain liquid crystalline polymers (Lc-/Sc-SCLCPs) have been synthesized
and characterized. The treatment of hydride siloxane-containing terminated
liquid crystalline and high 1,2-/1,4- (high vinyl, hv/low vinyl, lv)
linear or 4-arm star polybutadienes (L-/S-PBs) was conducted via the
methods in combination of living anionic polymerization and “reverse”
hydrosilylation to obtain SCLCPs with wide mesomorphic temperature
range (Δ<i>T</i>) and narrow polydispersity index
(PDI). The possible molecular arrangement model of two analogous hv-/lv-architectures
was constructed, that was used to systematically investigate the effects
of Lc- and Sc- topological morphology on liquid crystalline (LC) properties
and molecular microstructures. SCLCPs exhibited the same smectic A
phase around room temperature, but thermal properties were significantly
different due to differences of interaction force resulting from different
macromolecular side chains packing. Surprisingly, the trend of lv-SCLCP
displaying the effects of topology on phase transitions and microstructures
was just contrary to that of hv-topology. hv-Sc-SCLCPs containing
high density mesogenic composition were desired to generate wider
Δ<i>T</i> and higher molecular layer order in comparison
with Lc analogues, which provided a unexpected analyzed model that
are of interest to be explored. In particular, the uniaue differences
of macromolecular aggregation state arrangement in liquid crystal
state dependent on free cooling between hv-Lc- and Sc-SCLCPs were
observed from POM
Additional file 2 of Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling
Additional file 2. The images of the original, uncropped blots for the OxtR and GAPDH
Additional file 1 of Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling
Additional file 1: Fig. S1. The expression of OxtRs in mouse retina. Fig. S2. Example images showing OxtR-eYFP neurons are Brn3a (A) or melanopsin (B) positive in the GCL. Fig. S3. eYFP+ neurons in Oxtr-Cre; Ai3 mice are mainly GABAergic, but not glycinergic amacrine cells. Fig. S4. Distribution of OxtR-eYFP neurons in Oxtr-Cre; Ai3 mouse retina. Fig. S5. ChAT and CRH ACs are partially co-localized with OxtR-eYFP neurons, and oxytocin elevates DA level. Fig. S6. The effects of oxytocin and OxtR antagonist on the amplitude of ERG b-wave. Fig. S7. Effects of oxytocin on b-wave amplitude in the presence of V1AR or DA receptor antagonists
Postpolymerization Modification of Poly(dihydropyrimidin-2(1<i>H</i>)‑thione)s via the Thiourea–Haloalkane Reaction to Prepare Functional Polymers
A highly
reactive thiourea-contained polycondensate, polyÂ(dihydropyrimidin-2Â(1<i>H</i>)-thione) (polyÂ(DHPMT)) has been facilely synthesized via
the Biginelli polycondensation using thiourea and a difunctional compound
containing benzaldehyde and β-keto ester groups as monomers.
The thiourea moiety in the polymer structure has similar reactivity
as the thiourea, thus the polyÂ(DHPMT) is an excellent polymer precusor
for preparing new functional polymers through the postpolymerization
modification (PPM) strategy. After simple reaction with functional
haloalkanes, the parent polyÂ(DHPMT) could be almost completely converted
(>99%) to daughter polymers containing alkene or alkyne side groups.
Then, the daughter polymers have been further transferred to granddaughter
polymers through another PPM via thiol–ene or CuÂ(I)-catalyzed
azide–alkyne cycloaddition (CuAAC) reactions. Besides, when
3-phenylpropargyl chloride was used as the reactant, a bright yellow
fluorescent polymer could be simply achieved due to the in situ formed
conjugated heterocycle in the polymer structure, further demonstrating
the diversity of the functional polymers through PPM. Considering
the easily available monomers, simple polycondensation, and the excellent
reactivity of the thiourea moiety in the polymer structure, this thiourea-contained
Biginilli polycondensate might be a versatile platform for new functional
polymer preparation