Ultrasound-detected anatomical types of SNs.

<p>Ultrasound-detected anatomical types of SNs.</p

Anthropometric and biochemical parameters showing significant correlations with serum A-FABP and NT-proBNP after the 48-week rosiglitazone treatment.

<p><i>β</i>, Standardized regression coefficients.</p>†<p>Pearson correlation analyses were performed.</p><p>*A multiple stepwise regression analysis was performed. Variables included in the original model are age, gender, waist circumference, BMI, TC, TG, LDL-c, and NT-proBNP.</p>#<p>A multiple stepwise regression analysis was performed. Variables included in the original model are age, gender, BMI, SBP, HDL-c, FPG, fasting insulin, HOMA-IR, AIR, and A-FABP.</p

Receiver operating characteristic (ROC) curve of the US parameters.

<p>The green curve represents the maximum thickness of the neuronal fascicles (MT), the yellow curve represents the cross-sectional area (CSA), and the blue curve represents the thickness/width (T/W) ratio.</p

Image analysis on T/W ratio, CSA and MT of the SN.

<p>a) Transverse sonogram of the SN. b) Schematic diagram associated with the measurements.</p

Transverse and longitudinal sonograms of the SN.

<p>a) Transverse sonogram of the SN. A transverse sonogram showing the SN (arrows) near the lesser saphenous vein (V) SN appeared as an ovoid hypoechoic reticular structure with a hyperechoic rim. b) Longitudinal sonogram of the SN. A Longitudinal sonogram of the SN showing the perineurium (dashed arrows) and epineurium (solid arrow).</p

Changes in anthropometric and biochemical parameters showing significant correlations with changes in serum A-FABP and NT-proBNP during the 48-week rosiglitazone treatment.

<p>Δ, differences between after and before treatment.</p><p><i>β</i>, Standardized regression coefficients.</p>†<p>Pearson correlation analyses were performed.</p><p>*A multiple stepwise regression analysis was performed. Variables included in the original model are age, gender, Δ waist circumference, Δ TG, Δ HDL-c, and Δ NT-proBNP.</p>#<p>A multiple stepwise regression analysis was performed. Variables included in the original model are age, gender, Δ BMI, Δ fasting insulin, Δ HOMA-B%, and Δ A-FABP.</p

Anthropometric and biochemical parameters showing significant correlations with serum A-FABP and NT-proBNP at baseline.

<p><i>β</i>, Standardized regression coefficients.</p>†<p>Pearson correlation analyses were performed.</p><p>*A multiple stepwise regression analysis was performed. Variables included in the original model are age, gender, waist circumference, BMI, and LDL-c.</p>#<p>A multiple stepwise regression analysis was performed. Variables included in the original model are age, gender, SBP, TG, HDL-c, LDL-c, FPG, HbA1c, HOMA-IR, and AIR.</p

Clinical characteristics of study subjects.

<p>Data are mean ± SD or median (interquartile range). AIR: acute insulin response; BMI: body mass index; DBP, diastolic blood pressure; FPG: fasting plasma glucose; 2hPG: 2-h postchallenge plasma glucose; HbA1c: glycated hemoglobin A1c; HDL-c: high density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment index of insulin resistance; HOMA-B%: homeostasis model assessment index of beta cell function; LDL-c: low density lipoprotein cholesterol; SBP, systolic blood pressure; TC: total cholesterol; TG: triglyceride.</p>†<p>Log transformed before analysis.</p><p>*<i>P</i><0.01 vs. baseline.</p

Serum A-FABP and NT-proBNP concentrtions at baseline and after 24 and 48 weeks of rosiglitazone therapy in 84 patients with newly diagnosed T2DM.

<p>Data are median with interquartile range. A: Serum A-FABP levels at baseline and after 24 and 48 weeks of rosiglitazone therapy were 0.8 (0.4–1.3) ng/ml, 2.5 (1.4–3.9) ng/ml, and 5.0 (2.7–9.7) ng/ml for all patients, 0.7 (0.3–1.2) ng/ml, 2.5 (1.4–3.8) ng/ml, and 3.9 (2.4–8.1) ng/ml for men, and 0.9 (0.7–1.5) ng/ml, 2.6 (1.7–6.4) ng/ml, and 8.0 (4.0–12.4) ng/ml for women. B: Serum NT-proBNP levels at baseline and after 24 and 48 weeks of rosiglitazone therapy were 11.1 (5.0–30.3) ng/l, 17.6 (7.8–37.6) ng/l, and 20.0 (9.4–40.9) ng/l for all subjects, 9.7 (5.0–24.2) ng/l, 14.2 (5.3–32.3) ng/l, and 16.0 (6.7–30.1) ng/l for men, and 17.2 (9.0–39.2) ng/l, 30.7 (17.3–51.9) ng/l, and 46.1 (19.4–65.7) ng/l for women. * <i>P</i><0.01 versus baseline. ** <i>P</i><0.001 versus baseline. # <i>P</i><0.001 versus 24 weeks.</p

Comparison and statistical significance of the ultrasonographic parameters.

<p>Abbreviations: CSA, cross-sectional area; MT, the maximum thickness of the neuronal fascicles; T/W ratio, thickness/width ratio. All values in the three groups are the mean±standard deviation.</p