Metal–Organic Proximity in a Synthetic Pocket

Proximity between a noninteractive organic substrate and a transition metal (<i>trans</i>-MCl₂(PEt₃)₂; M = Pd or Pt) is achieved by their co-encapsulation within a synthetic cage, as revealed by X-ray crystallographic analysis and NOESY experiments. Through co-encapsulation with a Pd­(II) complex, a terminal alkyne was activated within the cage to give a σ-alkynylpalladium complex