Additional file 1 of Silencing of UBE2D1 inhibited cell migration in gastric cancer, decreasing ubiquitination of SMAD4

Additional file 1. The protein levels of E-cadherin and N-cadherin were measure after transduction of shUBE2D1 lentiviruses in AGS and MKN45 cells

Supplementary_material_1 – Supplemental material for Programmed death-ligand 1 and survival in colorectal cancers: A meta-analysis

Supplemental material, Supplementary_material_1 for Programmed death-ligand 1 and survival in colorectal cancers: A meta-analysis by Huihua Cao, Qing Wang, Zhenyan Gao, Zhan Yu, Yugang Wu and Qicheng Lu in The International Journal of Biological Markers</p

Supplementary_material_2 – Supplemental material for Programmed death-ligand 1 and survival in colorectal cancers: A meta-analysis

Supplemental material, Supplementary_material_2 for Programmed death-ligand 1 and survival in colorectal cancers: A meta-analysis by Huihua Cao, Qing Wang, Zhenyan Gao, Zhan Yu, Yugang Wu and Qicheng Lu in The International Journal of Biological Markers</p

MOESM1 of Clinical value of detecting IQGAP3, B7-H4 and cyclooxygenase-2 in the diagnosis and prognostic evaluation of colorectal cancer

Additional file 1. Correlation of serum IQGAP3, CEA and CA19-9 levels with clinicopathological features in 118 CRC patients. One hundred eighteen CRC patients who met the inclusion criteria were analyzed in this study. The correlation between clinicopathological characteristics and serum tumor markers were analyzed

Correlation of TLR4, MD-2, and CXCR7 expression with clinicopathologic features in colorectal carcinoma.

<p>Correlation of TLR4, MD-2, and CXCR7 expression with clinicopathologic features in colorectal carcinoma.</p

Proliferation, apoptosis and migration of CXCR7-positive SW480 and Colo 205 cell lines incubated with LPS.

<p>A, Incubation with LPS, SW480 cell line pretreated with AMD3100 (10 µg/ml) proliferated significantly in response to CXCL12 (100 ng/ml; 48 h), Colo 205 cell line also proliferated significantly in response to CXCL12. B, CXCL12 activation of its receptor CXCR7 did not exert an antiapoptotic effect. C, Pretreatment with AMD3100, SW480 cell line migrated significantly more in response to CXCL12 after 24 h of incubation with LPS, Colo 205 cell line also migrated significantly in response to CXCL12.</p

LPS-TLR4-MD-2 induced CXCR7 expression alteration in colorectal carcinoma cell line.

<p>A, Reverse transcriptase (RT)-PCR analysis (TLR4 and MD-2) on RNA isolated from 8 human colorectal carcinoma cell lines. B, LPS induced time- and dose-dependent CXCR7 and CXCR4 protein expression alterations. SW480 and Colo 205 cell lines were incubated with LPS (500 ng/ml) in the presence or absence of PMB (500 µg/ml), representative flow cytometric analysis of CXCR7 expression alterations were showed. C, LPS exposure induced a significant CXCR7 expression increase in total RNA conten. D, Exposure of SW480 and Colo 205 cell lines to LPS (500 ng/ml) had no effect on CXCR4 expression.</p

The simple and multiple logistic regression model analyzing the predictors of colorectal carcinoma lymph node metastasis.

<p>*ORs and 95% CIs were calculated by unconditional logistic regression after adjusting for age, sex, tumor size and histologic grade.</p

Knockdown effect of MD-2 on exposure of TLR4 to LPS in SW480 and Colo 205 cell lines.

<p>A, SW480 and Colo 205 cell lines were transfected transiently with siRNA or negative control sequence(NC). SW480 and Colo 205 cell lines transfected with the MD-2 siRNA sequence exhibited a marked reduction in MD-2 mRNA and protein level compared with NC. B, After LPS treatment, flow cytometry and real-time quantitative-PCR were performed. Knockdown of MD-2 inhibited LPS-mediated CXCR7 expression.</p

Correlation of combined high expression of TLR4, MD-2, and CXCR7 with tumor size and metastasis.

<p>Correlation of combined high expression of TLR4, MD-2, and CXCR7 with tumor size and metastasis.</p