DataSheet1_Human Papillomavirus and Retinoblastoma: Evidence From a Systematic Review and Meta-analysis of Cross-Sectional Studies.docx

Objectives: To study the prevalence and the association of HPV infection in retinoblastoma and to determine the most common genotype presented in RB.Methods: Following the PRIMSA guideline, 14 studies reporting HPV infection in RB acquired from six databases were included.Results: The prevalence of HPV from 941 RB samples was 15.6% [95% confidence interval (CI): 7.3–30]. Mexico followed by India and Brazil had the highest HPV prevalence in RB samples, 61.7% (95% CI: 17–93), 22.5% (95% CI: 9–47), and 12.1% (95% CI: 2–52), in order. HPV 16 was the most common genotype presented in RB samples 23% (95% CI: 9–47), followed by HPV 18 10% (95% CI: 3–30) and the combined HPV 16–18 6% (95% CI: 0–50). We did not find a significant association between HPV and RB [odds ratio (OR): 12.2; 95% CI: 0.65–232; p = 0.09]. However, after removing the largest-weighted study, a significant association between HPV and RB was observed (OR: 45.9; 95% CI; 8.6–245; p Conclusion: HPV prevalence in RB samples was 15% and HPV 16 was the most presented genotype in RB samples. There may be an association between HPV and RB that is needed to be confirmed by high quality future studies. Preventive and treatment measures against HPV infection are essential for the prevention of any possible consequences, in particular, RB.</p

Regioselective Synthesis of Highly Substituted Imidazoles via the Sequential Reaction of Allenyl Sulfonamides and Amines

A novel synthesis of imidazoles from electron-withdrawing group-substituted allenyl sulfonamides with amines was developed. The 4- and 5-functionalized imidazoles were constructed regioselectively, which depended on the substituents on the nitrogen atoms

Regioselective Synthesis of Highly Substituted Imidazoles via the Sequential Reaction of Allenyl Sulfonamides and Amines

A novel synthesis of imidazoles from electron-withdrawing group-substituted allenyl sulfonamides with amines was developed. The 4- and 5-functionalized imidazoles were constructed regioselectively, which depended on the substituents on the nitrogen atoms

Intrinsic connections between ROIs and modulatory effects on each connection.

**<p>Significance at <i>p</i><0.0125 (corrected for 4 comparisons);</p>*<p>Marginally significant tendency at <i>p</i><0.09.</p><p>FG, fusiform gyrus; IFG, inferior frontal gyrus; SPL, superior parietal lobule.</p

Brain activation maps for differences between conditions.

<p>TC, true character; RTC, radical-rearranged true characters; RPC, radical-rearranged pseudo-characters. Green: RTC/RPC greater than TC. Red: TC greater than RTC/RPC.</p

Overlapping activations for all character conditions compared to baseline condition.

<p>L, left hemisphere; R, right hemisphere; BA, Brodmann's areas; Areas in boldface indicate peaks of activation in the clusters. Significance at <i>p</i><0.05, FDR corrected.</p

Differential modulatory effects between task demands.

<p>A, ROI regions that showed the highest overlap across three conditions comparing to baseline at group level (FDR-corrected, <i>p</i><0.05); B, Yellow solid line arrows indicate influences modulated by lexical judgment, and blue dashed line arrows indicate influences modulated by spatial processing. FG, fusiform gyrus; IFG, inferior frontal gyrus; SPL, superior parietal lobule.</p

Percentage signal change in ROIs for each condition.

<p>TC, true character; RTC, radical-rearranged true characters; RPC, radical-rearranged pseudo-characters. FG, fusiform gyrus; IFG, inferior frontal gyrus; SPL, superior parietal lobule.</p

Examples of stimuli.

<p>TC, true character; RTC, radical-rearranged true characters; RPC, radical-rearranged pseudo-characters. For RTC, the second character is the true character, created by reversing the upper two radicals. English meaning and Chinese pronunciation (pinyin) for true characters are displayed in parenthesis. “+” and “−” indicate higher or lower involvements of factors.</p

Enhanced Dielectric Properties of Ferroelectric Polymer Composites Induced by Metal-Semiconductor Zn-ZnO Core–Shell Structure

The effect of metal-semiconductor Zn-ZnO core–shell structure on dielectric properties of polyvinylidene fluoride (PVDF) composites was investigated. Zn-ZnO fillers were obtained by the heat-treatment of raw Zn particles under air. The enhanced dielectric constant of Zn-ZnO/PVDF composites results from the duplex interfacial polarizations induced by metal-semiconductor interface and semiconductor–insulator interface. The dielectric loss is still low because of the presence of ZnO semiconductor shell between Zn metal core and insulator PVDF matrix. Furthermore, the dielectric performance of as-prepared composites could be further optimized through adjusting the thickness of semiconductor shell