Calculation of hyperfine splitting in mesons using configuration interaction approach

The spin - spin mass splitting of light, heavy and mixed mesons are described within a good accuracy in the potential model with screened potential. We conclude that the long - distance part of the potential cannot be pure scalar and that a vector - scalar mixture is favoured. With the same parameters which gives correct average mass spectrum excellent spin - spin splittings of heavy quarkonia is obtained. The results are obtained by going beyond usually used perturbation method, namely using configuration interaction approach.Comment: 8 pages, LaTe

A Parallel Distributed Strategy for Arraying a Scattered Robot Swarm

We consider the problem of organizing a scattered group of $n$ robots in two-dimensional space, with geometric maximum distance $D$ between robots. The communication graph of the swarm is connected, but there is no central authority for organizing it. We want to arrange them into a sorted and equally-spaced array between the robots with lowest and highest label, while maintaining a connected communication network. In this paper, we describe a distributed method to accomplish these goals, without using central control, while also keeping time, travel distance and communication cost at a minimum. We proceed in a number of stages (leader election, initial path construction, subtree contraction, geometric straightening, and distributed sorting), none of which requires a central authority, but still accomplishes best possible parallelization. The overall arraying is performed in $O(n)$ time, $O(n^2)$ individual messages, and $O(nD)$ travel distance. Implementation of the sorting and navigation use communication messages of fixed size, and are a practical solution for large populations of low-cost robots

Glueball Masses in Relativistic Potential Model

The problem of glueball mass spectra using the relativistic Dirac equation is studied. Also the Breit-Fermi approach used to obtaining hyperfine splitting in glueballs. Our approach is based on the assumption, that the nature and the forces between two gluons are the short-range. We were to calculate the glueball masses with used screened potential.Comment: 7 pages, LaTe

The role of relativistic kinematics in describing two-quark systems

An attempt to incorporate relativistic kinematics in the description of light quark systems is made. It seems that the way of such an incorporation suggested by R.Gaida and his collaborators is very promising. Comparison of these results with the experimental data concerning a boson mass spectrum shows that this approach is among the best theoretical interpretations of the data.Зроблено спробу врахувати релятивістичну кінематику у описі легких кваркових систем. Багатообіцяючим виглядає підхід до такого врахування, запропонований Р. Ґайдою та його співробітниками. Порівняння результатів з експериментальними даними, що стосуються спектру мас бозонів, показує, що цей підхід знаходиться серед кращих теоретичних інтерпретацій даних

Spin Effects in Two Quark System and Mixed States

Based on the numeric solution of a system of coupled channels for vector mesons ($S$- and $D$-waves mixing) and for tensor mesons ($P$- and $F$-waves mixing) mass spectrum and wave functions of a family of vector mesons $q\bar{q}$ in triplet states are obtained. The calculations are performed using a well known Cornell potential with a mixed Lorentz-structure of the confinement term. The spin-dependent part of the potential is taken from the Breit-Fermi approach. The effect of singular terms of potential is considered in the framework of the perturbation theory and by a configuration interaction approach (CIA), modified for a system of coupled equations. It is shown that even a small contribution of the $D$-wave to be very important at the calculation of certain characteristics of the meson states.Comment: 12 pages, LaTe

Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing

The universally conserved eukaryotic initiation factor (eIF), eIF1A, plays multiple roles throughout initiation: it stimulates eIF2/GTP/Met-tRNAiMet attachment to 40S ribosomal subunits, scanning, start codon selection and subunit joining. Its bacterial ortholog IF1 consists of an oligonucleotide/oligosaccharide-binding (OB) domain, whereas eIF1A additionally contains a helical subdomain, N-terminal tail (NTT) and C-terminal tail (CTT). The NTT and CTT both enhance ribosomal recruitment of eIF2/GTP/Met-tRNAiMet, but have opposite effects on the stringency of start codon selection: the CTT increases, whereas the NTT decreases it. Here, we determined the position of eIF1A on the 40S subunit by directed hydroxyl radical cleavage. eIF1A's OB domain binds in the A site, similar to IF1, whereas the helical subdomain contacts the head, forming a bridge over the mRNA channel. The NTT and CTT both thread under Met-tRNAiMet reaching into the P-site. The NTT threads closer to the mRNA channel. In the proposed model, the NTT does not clash with either mRNA or Met-tRNAiMet, consistent with its suggested role in promoting the ‘closed’ conformation of ribosomal complexes upon start codon recognition. In contrast, eIF1A-CTT appears to interfere with the P-site tRNA-head interaction in the ‘closed’ complex and is likely ejected from the P-site upon start codon recognition

Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing

The universally conserved eukaryotic initiation factor (eIF), eIF1A, plays multiple roles throughout initiation: it stimulates eIF2/GTP/Met-tRNAiMet attachment to 40S ribosomal subunits, scanning, start codon selection and subunit joining. Its bacterial ortholog IF1 consists of an oligonucleotide/oligosaccharide-binding (OB) domain, whereas eIF1A additionally contains a helical subdomain, N-terminal tail (NTT) and C-terminal tail (CTT). The NTT and CTT both enhance ribosomal recruitment of eIF2/GTP/Met-tRNAiMet, but have opposite effects on the stringency of start codon selection: the CTT increases, whereas the NTT decreases it. Here, we determined the position of eIF1A on the 40S subunit by directed hydroxyl radical cleavage. eIF1A's OB domain binds in the A site, similar to IF1, whereas the helical subdomain contacts the head, forming a bridge over the mRNA channel. The NTT and CTT both thread under Met-tRNAiMet reaching into the P-site. The NTT threads closer to the mRNA channel. In the proposed model, the NTT does not clash with either mRNA or Met-tRNAiMet, consistent with its suggested role in promoting the ‘closed’ conformation of ribosomal complexes upon start codon recognition. In contrast, eIF1A-CTT appears to interfere with the P-site tRNA-head interaction in the ‘closed’ complex and is likely ejected from the P-site upon start codon recognition

Fatigue Failure Analysis for Bolt-Nut Connections having Slight Pitch Differences using Experimental and Finite Element Methods

In this paper, fatigue failure is considered, for bolt-nut connections, when a slight pitch difference is introduced between the bolt and the nut. To improve the fatigue life, three types of pitch difference are produced on the specimens and the experimental results are compared and discussed in terms of FEM analysis. Considering the standard bolt-nutconnection of α=0 μm, the bolt fracture does not happen at the No. 1 thread by introducing a slight pitch difference of α=5 μm and α=15 μm, as observed from the experiments. Furthermore, it is found that the fatigue life can be extended by introducing suitable pitch differences. The effect of bolt-nut fitted clearance, on the fatigue failure is also investigated

GalR, GalX and AraR co-regulate d-galactose and l-arabinose utilization in Aspergillus nidulans

Filamentous fungi produce a wide variety of enzymes in order to efficiently degrade plant cell wall polysaccharides. The production of these enzymes is controlled by transcriptional regulators, which also control the catabolic pathways that convert the released monosaccharides. Two transcriptional regulators, GalX and GalR, control d-galactose utilization in the model filamentous fungus Aspergillus nidulans, while the arabinanolytic regulator AraR regulates l-arabinose catabolism. d-Galactose and l-arabinose are commonly found together in polysaccharides, such as arabinogalactan, xylan and rhamnogalacturonan I. Therefore, the catabolic pathways that convert d-galactose and l-arabinose are often also likely to be active simultaneously. In this study, we investigated the interaction between GalX, GalR and AraR in d-galactose and l-arabinose catabolism. For this, we generated single, double and triple mutants of the three regulators, and analysed their growth and enzyme and gene expression profiles. Our results clearly demonstrated that GalX, GalR and AraR co-regulate d-galactose catabolism in A. nidulans. GalX has a prominent role on the regulation of genes of d-galactose oxido-reductive pathway, while AraR can compensate for the absence of GalR and/or GalX.Peer reviewe

Genomic analysis of the function of the transcription factor gata3 during development of the Mammalian inner ear

We have studied the function of the zinc finger transcription factor gata3 in auditory system development by analysing temporal profiles of gene expression during differentiation of conditionally immortal cell lines derived to model specific auditory cell types and developmental stages. We tested and applied a novel probabilistic method called the gamma Model for Oligonucleotide Signals to analyse hybridization signals from Affymetrix oligonucleotide arrays. Expression levels estimated by this method correlated closely (p<0.0001) across a 10-fold range with those measured by quantitative RT-PCR for a sample of 61 different genes. In an unbiased list of 26 genes whose temporal profiles clustered most closely with that of gata3 in all cell lines, 10 were linked to Insulin-like Growth Factor signalling, including the serine/threonine kinase Akt/PKB. Knock-down of gata3 in vitro was associated with a decrease in expression of genes linked to IGF-signalling, including IGF1, IGF2 and several IGF-binding proteins. It also led to a small decrease in protein levels of the serine-threonine kinase Akt2/PKB beta, a dramatic increase in Akt1/PKB alpha protein and relocation of Akt1/PKB alpha from the nucleus to the cytoplasm. The cyclin-dependent kinase inhibitor p27(kip1), a known target of PKB/Akt, simultaneously decreased. In heterozygous gata3 null mice the expression of gata3 correlated with high levels of activated Akt/PKB. This functional relationship could explain the diverse function of gata3 during development, the hearing loss associated with gata3 heterozygous null mice and the broader symptoms of human patients with Hearing-Deafness-Renal anomaly syndrome